Prenatal alcohol exposure affects renal function in overweight schoolchildren: birth cohort analysis

2019 ◽  
Vol 35 (4) ◽  
pp. 695-702
Author(s):  
Liane Correia-Costa ◽  
Franz Schaefer ◽  
Alberto Caldas Afonso ◽  
Sofia Correia ◽  
João Tiago Guimarães ◽  
...  
Keyword(s):  
Renal Function ◽  
Birth Cohort ◽  
Prenatal Alcohol Exposure ◽  
Cohort Analysis ◽  
Alcohol Exposure ◽  
Prenatal Alcohol ◽  
Birth Cohort Analysis

scholarly journals Prenatal alcohol exposure is associated with early motor, but not language development in a South African cohort

2020 ◽  
Vol 32 (3) ◽  
pp. 145-152
Author(s):  
Gaironeesa Hendricks ◽  
Susan Malcolm-Smith ◽  
Dan J. Stein ◽  
Heather J. Zar ◽  
Catherine J. Wedderburn ◽  
...  
Keyword(s):  
Language Development ◽  
South African ◽  
Birth Cohort ◽  
Psychosocial Factors ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Health Study ◽  
Fine Motor ◽  
Birth Cohort Study ◽  
Prenatal Alcohol

AbstractObjective:To investigate the association of prenatal alcohol exposure (PAE) and early neurodevelopment in the first 2 years of life, adjusting for maternal socio-demographic and psychosocial factors, in the Drakenstein Child Health Study (DCHS), a South African birth cohort study.Methods:The DCHS comprises a population-based birth cohort of 1143 children, of which a subsample completed the Bayley Scales of Infant Development-III (BSID-III) at 6 (n = 260) and 24 months of age (n = 734). A subset of alcohol-exposed and -unexposed children was included in this analysis at age 6 (n = 52 exposed; n = 104 unexposed) and 24 months (n = 92 exposed; n = 184 unexposed). Multiple hierarchical regression was used to explore the associations of PAE with motor and language development.Results:PAE was significantly associated with decreased gross motor [odds ratio (OR) = 0.16, 95% confidence interval (CI) = 0.06–0.44, p = 0.001] or fine motor (OR = 0.16, 95% CI = 0.06–0.46, p = 0.001) functioning after adjusting for maternal socio-demographic and psychosocial factors at 6 months of age only. No significant effects were found in either receptive or expressive communication and cognitive outcomes at either time points.Conclusion:PAE has potentially important consequences for motor development in the first 2 years of life, a period during which the most rapid growth and maturation occur. These findings highlight the importance of identifying high-risk families in order to provide preventive interventions, particularly in antenatal clinics and early intervention services.

scholarly journals Prenatal alcohol exposure and childhood balance ability: findings from a UK birth cohort study

BMJ Open ◽  
2013 ◽  
Vol 3 (6) ◽  
pp. e002718 ◽  
Author(s):  
Rachel Humphriss ◽  
Amanda Hall ◽  
Margaret May ◽  
Luisa Zuccolo ◽  
John Macleod
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Birth Cohort Study ◽  
Balance Ability ◽  
Prenatal Alcohol

Complex Trauma and Prenatal Alcohol Exposure: Clinical Implications

2012 ◽  
Vol 13 (2) ◽  
pp. 32-42 ◽  
Author(s):  
Yvette D. Hyter
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Child Development ◽  
Academic Outcomes ◽  
Complex Trauma ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Clinical Implications ◽  
Prenatal Alcohol ◽  
The Brain

Abstract Complex trauma resulting from chronic maltreatment and prenatal alcohol exposure can significantly affect child development and academic outcomes. Children with histories of maltreatment and those with prenatal alcohol exposure exhibit remarkably similar central nervous system impairments. In this article, I will review the effects of each on the brain and discuss clinical implications for these populations of children.

Prenatal alcohol exposure and signs of minor neurological dysfunction at preschool age

2000 ◽  
Vol 42 (8) ◽  
pp. 508-514 ◽  
Author(s):  
Béatrice Larroque ◽  
Monique Kaminski ◽  
Phillipe Dehaene ◽  
Damien Subtil ◽  
Denis Querleu
Keyword(s):  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Preschool Age ◽  
Neurological Dysfunction ◽  
Minor Neurological Dysfunction ◽  
Prenatal Alcohol

Impact of Moderate Prenatal Alcohol Exposure on Problem Behaviors in Preschool and School Children

2014 ◽  
Vol 46 (2) ◽  
pp. 89-100 ◽  
Author(s):  
Manuela Pfinder ◽  
Stefan Liebig ◽  
Reinhold Feldmann
Keyword(s):  
Problem Behaviors ◽  
Tobacco Smoke ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Smoke Exposure ◽  
Low Ses ◽  
German Health ◽  
Kiggs Study ◽  
Strengths And Difficulties ◽  
Prenatal Alcohol

Data on the relation between moderate prenatal alcohol exposure (PAE) and behavioral disorders are inconsistent, and this raises new questions. We examined (1) the association between moderate PAE and problem behaviors and (2) whether these associations differed by levels of socioeconomic status (SES), fetal smoke exposure, or exposure to environmental tobacco smoke (ETS). Data were taken from the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) study. Parents evaluated children’s behaviors using the Strengths and Difficulties Questionnaire (SDQ). Results showed a slight, but insignificant, increase of problem behaviors in children with moderate PAE. In 3- to 6-year-olds, PAE had a stronger effect on hyperactivity/inattention in combination with fetal smoke exposure (odds ratio = 2.82), than did PAE alone. Effects were not stronger in low-SES children, but they were stronger in children with ETS. We conclude that moderate PAE might have adverse effects on neurodevelopment, with stronger effects in disadvantaged populations. To confirm our preliminary findings, further research should be conducted.

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