Assessment of antioxidant and cutaneous wound healing effects of Falcaria vulgaris aqueous extract in Wistar male rats

2018 ◽  
Vol 28 (2) ◽  
pp. 435-445 ◽  
Author(s):  
Samaneh Goorani ◽  
Mohammad Mahdi Zangeneh ◽  
Mohammad Kazem Koohi ◽  
Niloofar Seydi ◽  
Akram Zangeneh ◽  
...  
Keyword(s):  
Wound Healing ◽  
Aqueous Extract ◽  
Male Rats ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound ◽  
Falcaria Vulgaris ◽  
Wistar Male Rats

Therapeutic effects of Glycyrrhiza glabra aqueous extract ointment on cutaneous wound healing in Sprague Dawley male rats

2019 ◽  
Vol 28 (5) ◽  
pp. 1507-1514 ◽  
Author(s):  
Akram Zangeneh ◽  
Mehrdad Pooyanmehr ◽  
Mohammad Mahdi Zangeneh ◽  
Rohallah Moradi ◽  
Raheleh Rasad ◽  
...  
Keyword(s):  
Wound Healing ◽  
Aqueous Extract ◽  
Glycyrrhiza Glabra ◽  
Male Rats ◽  
Therapeutic Effects ◽  
Cutaneous Wound Healing ◽  
Sprague Dawley ◽  
Cutaneous Wound

scholarly journals Both obesity-prone and obesity-resistant rats present delayed cutaneous wound healing

2011 ◽  
Vol 106 (4) ◽  
pp. 603-611 ◽  
Author(s):  
Adriana Paulino do Nascimento ◽  
Andréa Monte-Alto-Costa
Keyword(s):  
Wound Healing ◽  
Saturated Fat ◽  
Inflammatory Cells ◽  
Male Rats ◽  
Control Group ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound ◽  
Diet Induced Obesity ◽  
Tnf Α ◽  
Obesogenic Diet

Diet-induced overweight rats exhibit delayed cutaneous healing; however, when receiving an obesogenic diet, some rats are susceptible to developing the overweight phenotype, whereas others are resistant. We investigated cutaneous healing in diet-induced obesity (DIO)-prone and diet-resistant (DR) rats. Male rats were fed with a standard (control) or a high-saturated fat (30 % fat, w/w) diet for 20 weeks. Then, the experimental group was subdivided into DIO (n 17) and DR (n 16) groups. An excision lesion was made, and the animals were killed 7 or 14 d later. The average body weight was 29 and 25 % higher in the DIO group compared with the C and DR groups. Retroperitoneal fat was higher in the DIO group than in the control and DR groups (518 and 92 %) and was higher in the DR group than in the control group (223 %). The DIO group presented glucose intolerance, and both the DIO and DR groups presented delayed wound contraction (50 %) and re-epithelialisation (20 %). Compared with the DR group, the DIO group displayed higher amounts of inflammatory cells as well as higher levels of lipid peroxidation (P < 0·05). Myofibroblastic differentiation and vessel remodelling were delayed in both the DIO and DR groups. Nitrite levels were lower in the DIO group (340 % less) than in the DR group. TNF-α expression was increased in the DIO group (130 %) compared with the DR group. Our results showed that DIO as well as DR rats present delays in cutaneous wound healing, even though the DR group does not have an overweight phenotype.

Evaluation of cutaneous wound healing activity of Ocimum basilicum aqueous extract ointment in rats

2019 ◽  
Vol 28 (5) ◽  
pp. 1447-1454
Author(s):  
Mohammad Mahdi Zangeneh ◽  
Akram Zangeneh ◽  
Niloofar Seydi ◽  
Rohallah Moradi
Keyword(s):  
Wound Healing ◽  
Aqueous Extract ◽  
Ocimum Basilicum ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound ◽  
Wound Healing Activity
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