scholarly journals Clinical features of conjoined lumbosacral nerve roots versus lumbar intervertebral disc herniations

2010 ◽  
Vol 19 (7) ◽  
pp. 1094-1098 ◽  
Author(s):  
R. Lotan ◽  
A. Al-Rashdi ◽  
A. Yee ◽  
J. Finkelstein
2020 ◽  
Vol 21 (11) ◽  
pp. 3748
Author(s):  
Loïc Treffel ◽  
Nastassia Navasiolava ◽  
Karen Mkhitaryan ◽  
Emmanuelle Jouan ◽  
Kathryn Zuj ◽  
...  

Most astronauts experience back pain after spaceflight, primarily located in the lumbar region. Intervertebral disc herniations have been observed after real and simulated microgravity. Spinal deconditioning after exposure to microgravity has been described, but the underlying mechanisms are not well understood. The dry immersion (DI) model of microgravity was used with eighteen male volunteers. Half of the participants wore thigh cuffs as a potential countermeasure. The spinal changes and intervertebral disc (IVD) content changes were investigated using magnetic resonance imaging (MRI) analyses with T1-T2 mapping sequences. IVD water content was estimated by the apparent diffusion coefficient (ADC), with proteoglycan content measured using MRI T1-mapping sequences centered in the nucleus pulposus. The use of thigh cuffs had no effect on any of the spinal variables measured. There was significant spinal lengthening for all of the subjects. The ADC and IVD proteoglycan content both increased significantly with DI (7.34 ± 2.23% and 10.09 ± 1.39%, respectively; mean ± standard deviation), p < 0.05). The ADC changes suggest dynamic and rapid water diffusion inside IVDs, linked to gravitational unloading. Further investigation is needed to determine whether similar changes occur in the cervical IVDs. A better understanding of the mechanisms involved in spinal deconditioning with spaceflight would assist in the development of alternative countermeasures to prevent IVD herniation.


2019 ◽  
Vol 10 (1) ◽  
pp. 57
Author(s):  
Sait Ozturk ◽  
Hakan Cakin ◽  
Fatih Demir ◽  
Serdal Albayrak ◽  
Bekir Akgun ◽  
...  

Author(s):  
Raghu N. Natarajan ◽  
Mohammed Qasim ◽  
Howard An ◽  
Gunnar B. J. Andersson

Structural alterations of the disc are accompanied by changes in disc tissue structure and composition during degeneration processes. Human cadaver studies have shown that the probability of presence of annular tear is 0.6 in the age group 30 to 34 which increases to 0.85 in the 60 year age group. Among different phenomena that occur during disc degeneration, annular radial tears are commonly associated with disc herniations. The effect of increase in size of radial micro tear in the lumbar discs on the change in biomechanics of the disc is an area where there is very little information currently in the literature.


2020 ◽  
pp. 219256822093621
Author(s):  
Daniel T. Lilly ◽  
Mark A. Davison ◽  
Cody M. Eldridge ◽  
Ravinderjit Singh ◽  
Eric Y. Montgomery ◽  
...  

Study Design: Retrospective cohort study. Objective: To compare the utilization of conservative treatments in patients with lumbar intervertebral disc herniations who were successfully managed nonoperatively versus patients who failed conservative therapies and elected to undergo surgery (microdiscectomy). Methods: Clinical records from adult patients with an initial herniated lumbar disc between 2007 and 2017 were selected from a large insurance database. Patients were divided into 2 cohorts: patients treated successfully with nonoperative therapies and patients that failed conservative management and opted for microdiscectomy surgery. Nonoperative treatments utilized by the 2 groups were collected over a 2-year surveillance window. “Utilization” was defined by cost billed to patients, prescriptions written, and number of units disbursed. Results: A total of 277 941 patients with lumbar intervertebral disc herniations were included. Of these, 269 713 (97.0%) were successfully managed with nonoperative treatments, while 8228 (3.0%) failed maximal nonoperative therapy (MNT) and underwent a lumbar microdiscectomy. MNT failures occurred more frequently in males (3.7%), and patients with a history of lumbar epidural steroid injections (4.5%) or preoperative opioid use (3.6%). In a logistic multivariate regression analysis, male sex and utilization of opioids were independent predictors of conservative management failure. Furthermore, a cost analysis indicated that patients who failed nonoperative treatments billed for nearly double ($1718/patient) compared to patients who were successfully treated ($906/patient). Conclusion: Our results suggest that the majority of patients are successfully managed nonoperatively. However, in the subset of patients that fail conservative management, male sex and prior opioid use appear to be independent predictors of treatment failure.


2017 ◽  
Vol 16 (6) ◽  
pp. 9487-9493 ◽  
Author(s):  
Yuan Wang ◽  
Yong Yang ◽  
Jing-Chuan Sun ◽  
Qin-Jie Kong ◽  
Hai-Bo Wang ◽  
...  

Spine ◽  
1998 ◽  
Vol 23 (15) ◽  
pp. 1645-1648 ◽  
Author(s):  
Hemlata K. Pokharna ◽  
Frank M. Phillips

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