Recent progress in electrochemical sensing of cardiac troponin by using nanomaterial-induced signal amplification

2017 ◽  
Vol 184 (6) ◽  
pp. 1573-1585 ◽  
Author(s):  
Qinglin Sheng ◽  
Xiujuan Qiao ◽  
Ming Zhou ◽  
Jianbin Zheng
RSC Advances ◽  
2020 ◽  
Vol 10 (60) ◽  
pp. 36396-36403
Author(s):  
Mingjian Lang ◽  
Dan Luo ◽  
Guangyi Yang ◽  
Quanxi Mei ◽  
Guangjun Feng ◽  
...  

We have developed an ultrasensitive and highly specific electrochemical sensing platform for the detection of cardiac troponin I (cTnI), a recognized biomarker for the diagnosis of acute myocardial infarction (AMI) and related cardiovascular diseases (CVDs).


2017 ◽  
Vol 100 (4) ◽  
pp. 950-961 ◽  
Author(s):  
María Pedrero ◽  
Susana Campuzano ◽  
José M Pingarrón

Abstract The determination of organic and inorganic environmental and food pollutants is a key matter of concern in analytical chemistry due to their effects as a serious threat to human health. Focusing on this issue, several methodologies involving the use of nanostructured electrochemical platforms have been recently reported in the literature. Among these methods, those employing the use of quantum dots (QDs) stand out because of features such as signal amplification, good reproducibility and selectivity, and the possibility for multiplexed detection, and because they preserve the outstanding characteristics of electrochemical methodologies with respect to simplicity, ease-of-use, and cost-effective instrumentation. This review describes recent electrochemical strategies, in which design QDs play a key role, for the determination of pollutants in food and environmental samples. The particular role of QDs in the reported methodologies, their preparation, and the electrochemical platform design, as well as the advantages that QDs provide in the analysis of target analytes, are critically discussed.


The Analyst ◽  
2020 ◽  
Vol 145 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Jun-Tao Cao ◽  
Xiao-Long Fu ◽  
Fu-Rao Liu ◽  
Shu-Wei Ren ◽  
Yan-Ming Liu

A novel spatial-resolved electrochemiluminescent (ECL) ratiometry for cardiac troponin I (cTnI) analysis was developed using resonance energy transfer (RET) and a coreactant consumption strategy for signal amplification.


Sign in / Sign up

Export Citation Format

Share Document