Olfactory identification in non-demented elderly population and in mild cognitive impairment: a comparison of performance in clinical odor identification versus Boston Naming Test

2009 ◽  
Vol 116 (7) ◽  
pp. 891-895 ◽  
Author(s):  
Mikko P. Laakso ◽  
Susanna Tervo ◽  
Tuomo Hänninen ◽  
Matti Vanhanen ◽  
Merja Hallikainen ◽  
...  
2018 ◽  
Vol 23 (7) ◽  
pp. 840-850 ◽  
Author(s):  
Daruj Aniwattanapong ◽  
Sookjaroen Tangwongchai ◽  
Thitiporn Supasitthumrong ◽  
Solaphat Hemrunroj ◽  
Chavit Tunvirachaisakul ◽  
...  

2001 ◽  
Vol 13 (3) ◽  
pp. 289-298 ◽  
Author(s):  
Tom Bschor ◽  
Klaus-Peter Kühl ◽  
Friedel M. Reischies

This article discusses the potential of three assessments of language function in the diagnosis of Alzheimer-type dementia (DAT). A total of 115 patients (mean age 65.9 years) attending a memory clinic were assessed using three language tests: a picture description task (Boston Cookie-Theft picture), the Boston Naming Test, and a semantic and phonemic word fluency measure. Results of these assessments were compared with those of clinical diagnosis including the Global Deterioration Scale (GDS). The patients were classified by ICD-10 diagnosis and GDS stage as without cognitive impairment (n = 40), mild cognitive impairment (n = 34), mild DAT (n = 21), and moderate to severe DAT (n = 20). Hypotheses were (a) that the complex task of a picture description could more readily identify language disturbances than specific language tests and that (b) examination of spontaneous speech could help to identify patients with even mild forms of DAT. In the picture description task, all diagnostic groups produced an equal number of words. However, patients with mild or moderate to severe DAT described significantly fewer objects and persons, actions, features, and localizations than patients without or with mild cognitive impairment. Persons with mild cognitive impairment had results similar to those without cognitive impairment. The Boston Naming Test and both fluency measures were superior to the picture description task in differentiating the diagnostic groups. In sum, both hypotheses had to be rejected. Our results confirm that DAT patients have distinct semantic speech disturbances whereas they are not impaired in the amount of produced speech.


2010 ◽  
Vol 16 (6) ◽  
pp. 1099-1107 ◽  
Author(s):  
MARCIO LUIZ FIGUEREDO BALTHAZAR ◽  
CLARISSA LIN YASUDA ◽  
FABRÍCIO RAMOS SILVESTRE PEREIRA ◽  
FELIPE PAULO GUAZZI BERGO ◽  
FERNANDO CENDES ◽  
...  

AbstractNaming difficulties are characteristic of Alzheimer’s disease (AD) and, to a lesser extent, of amnestic mild cognitive impairment (aMCI) patients. The association of naming impairment with anterior temporal lobe (ATL) atrophy in Semantic Dementia (SD) could be a tip of the iceberg effect, in which case the atrophy is a marker of more generalized temporal lobe pathology. Alternatively, it could reflect the existence of a functional gradient within the temporal lobes, wherein more anterior regions provide the basis for greater specificity of representation. We tested these two hypotheses in a study of 15 subjects with mild AD, 17 with aMCI, and 16 aged control subjects and showed that coordinate and circumlocutory semantic error production on the Boston Naming Test was weakly correlated with ATL gray matter density, as determined by voxel-based morphometry. Additionally, we investigated whether these errors were benefited by phonemic cues, and similarly to SD, our AD patients had small improvement. Because there is minimal gradient of temporal lobe atrophy in AD or MCI, and, therefore, no basis for a tip of the iceberg effect, these findings support the theory of a modest functional gradient in the temporal lobes, with the ATLs being involved in the naming of more specific objects. (JINS, 2010, 16, 1099–1107.)


2015 ◽  
Vol 9 (3) ◽  
pp. 265-269 ◽  
Author(s):  
Valéria Trunkl Serrao ◽  
Sônia Maria Dozzi Brucki ◽  
Kenia Repiso Campanholo ◽  
Letícia Lessa Mansur ◽  
Ricardo Nitrini ◽  
...  

Objective: The objective of this study was to describe the performance of healthy elderly patients with aging-related pathologies (MCI) and patients with AD on a lexical decision test. Methods: The study included 38 healthy elderly subjects, 61 MCI and 26 AD patients from the Neurology Department of the Hospital das Clinicas, Behavioral and Cognitive Neurology Group. The neuropsychological instruments included the episodic memory test (RAVLT), subtests from the WAIS-III (Matrix Reasoning and Vocabulary) to determine estimated IQ, the Boston naming test (BNT) and Lexical Decision Test (LDT). Results: All groups differed on the MMSE, as expected according to their pathologies, memory tests, naming and estimated IQ. For the vocabulary and the LDT - measures of crystalized intelligence no differences were found. Conclusion: The LDT demonstrated that lexical decision can be used as a measure of pre-morbid IQ among the individuals assessed in a Brazilian sample.


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