Picture description in the assessment of connected speech intelligibility in Parkinson's disease: A pilot study

Introduction: Assessment of intelligibility in dysarthria tends to rely on oral reading of sentences or words. However, self-generated utterances are closer to a clients’ natural speech. This study investigated how transcription of utterances elicited by picture description can be used in the assessment of intelligibility in speakers with Parkinson’s disease. Methods: Speech samples from eleven speakers with Parkinson’s disease and six neurologically healthy persons were audio-recorded. Forty-two naive listeners completed transcriptions of self-generated sentences from a picture description task and orally read sentences from the Swedish Test of Intelligibility, as well as scaled ratings of narrative speech samples. Results: Intelligibility was higher in orally read than self-generated sentences and higher for content words than for the whole sentence in self-generated sentences for most of the speakers, although these within-group differences were not statistically significant at group level. Adding contextual leads for the listeners increased intelligibility in self-generated utterances significantly, but with individual variation. Although correlations between the intelligibility measures were at least moderate or strong, there was a considerable inter- and intra-speaker variability in intelligibility scores between tasks for the speakers with Parkinson’s disease, indicating individual variation of factors that impact intelligibility. Intelligibility scores from neurologically healthy speakers were generally high across tasks with no significant differences between the conditions. Discussion/Conclusion: Within-speaker variability support literature recommendations to use multiple methods and tasks when assessing intelligibility. The inclusion of transcription of self-generated utterances elicited by picture description to the intelligibility assessment has the potential to provide additional information to assessment methods based on oral reading of pre-scripted sentences, and to inform the planning of interventions.

Spatio-Semantic Graphs From Picture Description: Applications to Detection of Cognitive Impairment

Clinical assessments often use complex picture description tasks to elicit natural speech patterns and magnify changes occurring in brain regions implicated in Alzheimer's disease and dementia. As The Cookie Theft picture description task is used in the largest Alzheimer's disease and dementia cohort studies available, we aimed to create algorithms that could characterize the visual narrative path a participant takes in describing what is happening in this image. We proposed spatio-semantic graphs, models based on graph theory that transform the participants' narratives into graphs that retain semantic order and encode the visuospatial information between content units in the image. The resulting graphs differ between Cognitively Impaired and Unimpaired participants in several important ways. Cognitively Impaired participants consistently scored higher on features that are heavily associated with symptoms of cognitive decline, including repetition, evidence of short-term memory lapses, and generally disorganized narrative descriptions, while Cognitively Unimpaired participants produced more efficient narrative paths. These results provide evidence that spatio-semantic graph analysis of these tasks can generate important insights into a participant's cognitive performance that cannot be generated from semantic analysis alone.

A Linguistic Profile of Narrative Speech in Early and Late-Onset Alzheimer’s Disease

Objective. Alzheimer’s Dementia is defined as multiple impairments in cognitive functions and language impairment is one of the observed problems in this disease. In order to analyse these problems, narrative speech transcriptions of Turkish patients with early and late-onset Alzheimer’s Disease (AD) and an age/education-matched control group were examined. Materials & Methods. By using different language tests, the sentence production of Turkish patients with early (n: 23) and late-onset (n: 39) was examined and the results were compared within groups and within language tests. Our aim was to reveal the differences in sentence processing of Turkish Alzheimer patients. Results. According to the results, Turkish Alzheimer patients use short and simple sentences composed of fewer words in their speech. It was determined that these patients performed better in Picnic Picture Description test, which is thought to be easy to describe. In Cookie Theft Picture Description test, which is a complex one, and in the Subject-based Narration test, it was found that the speech amounts of AD patients were less. It was revealed that early-onset AD patients used shorter sentences including fewer words compared to late-onset AD patients. Conclusion. In the light of the data obtained, it can be said that AD patients have different sentence processing than normal individuals because of the problems in the language and memory areas of the disease. The fact that sentence processing is different means that these patients do not prefer the types of sentences that normal individuals prefer in their speeches, and use less words and simpler sentences.

Picture Description of the Western Aphasia Battery Picnic Scene: Reference Data for the French Canadian Population

Purpose The main aim of this study is to provide French Canadian reference data for quantitative measures extracted from connected speech samples elicited by the Western Aphasia Battery–Revised picnic scene, a discourse task frequently used in clinical assessment of acquired language disorders. Method Our sample consisted of 62 healthy French Canadian adults divided in two age groups: a 50- to 69-year-old group and a 70- to 90-year-old group. Results High interrater reliability scores were obtained for most of the variables. Most connected speech variables did not demonstrate an age effect. However, the 70- to 90-year-old group produced more repetitions than the 50- to 69-year-old group and displayed reduced communication efficiency (number of information content units per minute). Conclusion These findings contribute to building a reference data set to analyze descriptive discourse production in clinical settings.

Study on the (3+1)-dimensional KP equation with lump solution and its collision phenomena

The (3+1)-dimensional Kadomtsev–Petviashvili (KP) equation is studied in this paper by constructing the Hirota bilinear form. The lump solution of the equation is obtained by bilinear form, and the conditions for the existence of the solution are obtained. The picture description of lump solution is further given. On the other hand, we also give the collision phenomena of lump solution, periodic wave solution and a single-kink soliton solution when the (3+1)-dimensional KP equation reduces to [Formula: see text] and [Formula: see text] by means of the Hirota method. The collision phenomenon is shown in the 3D plot description, the dynamic characteristics of the collision are also analyzed.

A STUDY ON PATTERN OF CODE MIXING IN A SEQUENTIAL BILINGUAL YOUNG ADULTS

The present study aimed to investigate and compares the pattern of Code Mixing in Sequential bilingual young adult. Thirty Sequential bilingual (Tamil-English) adults between the age range of 18-25 years were participated in this study. The bilingual participants were asked to describe the cookie-theft picture in Tamil. The patterns of Code Mixing (Intra Sentential Mixing and Intra Lexical Mixing) were analysed from the collected data. The results showed sequential bilingual adult uses 4.8% of Intra Sentential Mixing and 5.3% of Intra Lexical Mixing. In pattern of Code Mixing, Intra Sentential Mixing found to more in women. The present study concluded that Sequential bilingual speaker uses slightly higher percentage of Intra Lexical Mixing when compared to Intra Sentential Mixing in the picture description task. This finding will help Speech Language Pathologist to plan assessment, intervention and to development appropriate material for Sequential bilingual speakers in making clinical decision.

The effects of proactive form-focused instruction and individual differences on second language acquisition

This study investigated the extent to which second language (L2) learners benefited from proactive form-focused instruction (FFI) targeting French grammatical gender attribution and the degree to which L2 learners’ attention control and working memory predicted their learning gains. A total of 102 L2 learners received either proactive FFI targeting French grammatical gender attribution or their regular instruction (i.e. control condition) for six 80-minute instructional sessions. A pretest, an immediate posttest, and a delayed posttest were administered, each entailing binary-choice, text-completion, picture-description, and listening tasks. The L2 learners also completed the Simon Test and the Corsi Block-Tapping Test, which measured their attention control and working memory. Results showed that L2 learners receiving the proactive FFI condition significantly outperformed those receiving the control condition in all tasks after the instructional sessions. More importantly, L2 learners’ attention control and working memory were significant predictors of their learning gains in the binary-choice and listening tasks, but not in the text-completion and picture-description tasks. The current study highlighted the roles of L2 learners’ attention control and working memory in proactive FFI.

Improved morpho-syntax in discourse following intensive voice treatment in Parkinson's disease: Secondary outcome variables from a Randomized Controlled Trial (RCT)

It is well established that voice is disordered in nearly 90% of individuals with Parkinsons disease (PD). Given the role of voice in language expression, we pose that optimizing vocal function may lead to improved language production. Verb production is an area of language deficit in PD, particularly for verbs associated with an individuals location of impairment (upper vs. lower limbs). It is thought that damage to the motor system, given its connection to action verbs, underlies this lexical effect. If this is the case, then treatment improving vocal motor function may also improve access to verbs. Nineteen participants with PD underwent Lee Silverman Voice Treatment (LSVT LOUD), a 4-week intensive voice treatment (TXPD), in an IRB-approved randomized controlled voice treatment trial. Language production was contrasted with 20 untreated PD (UNTXPD) and 20 age-matched neurotypical control participants. Each provided 1-minute picture description narratives at baseline and after 4-weeks. Pre-post treatment within- and between-group comparisons identified effects of assessment time point and isolated treatment effects in the TXPD relative to UNTXPD and Controls. Given the intervention, the TXPD group demonstrated a significant increase in loudness during the picture description, as well as increased utterance length, diversity of word types used, verbs per utterance, and lexical density.