scholarly journals Correction to: Salidroside exhibits anti-dengue virus activity by upregulating host innate immune factors

2021 ◽  
Author(s):  
Navita Sharma ◽  
K. P. Mishra ◽  
Lilly Ganju
Keyword(s):  
Dengue Virus ◽  
Innate Immune ◽  
Virus Activity ◽  
Immune Factors

Salidroside exhibits anti-dengue virus activity by upregulating host innate immune factors

2016 ◽  
Vol 161 (12) ◽  
pp. 3331-3344 ◽  
Author(s):  
Navita Sharma ◽  
K. P. Mishra ◽  
Lilly Ganju
Keyword(s):  
Dengue Virus ◽  
Innate Immune ◽  
Virus Activity ◽  
Immune Factors

The role of innate immune factors in acute myeloid leukemia before and after chemotherapy

Therapy ◽  
2021 ◽  
Vol 4_2021 ◽  
pp. 41-47
Author(s):  
Vinnitskaya A.B. Vinnitskaya ◽  
Svitich O.A. Svitich ◽  
Golenkov A.K. Golenkov ◽  
Klinushkina E.F. Klinushkina ◽  
Zaitseva T.A. Zaitseva ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Innate Immune ◽  
Before And After ◽  
Immune Factors ◽  
Acute Myeloid

scholarly journals An inducible heat shock protein 70 small molecule inhibitor demonstrates anti-dengue virus activity, validating Hsp70 as a host antiviral target

2016 ◽  
Vol 130 ◽  
pp. 81-92 ◽  
Author(s):  
Matthew K. Howe ◽  
Brittany L. Speer ◽  
Philip F. Hughes ◽  
David R. Loiselle ◽  
Subhash Vasudevan ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Dengue Virus ◽  
Small Molecule ◽  
Heat Shock Protein 70 ◽  
Small Molecule Inhibitor ◽  
Virus Activity ◽  
Molecule Inhibitor

scholarly journals Acute dengue virus 2 infection in Gabonese patients is associated with an early innate immune response, including strong interferon alpha production

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Pierre Becquart ◽  
Nadia Wauquier ◽  
Dieudonné Nkoghe ◽  
Angélique Ndjoyi-Mbiguino ◽  
Cindy Padilla ◽  
...  
Keyword(s):  
Immune Response ◽  
Dengue Virus ◽  
Interferon Alpha ◽  
Innate Immune Response ◽  
Innate Immune ◽  
Alpha Production

scholarly journals Sex and Death: The Effects of Innate Immune Factors on the Sexual Reproduction of Malaria Parasites

2011 ◽  
Vol 7 (3) ◽  
pp. e1001309 ◽  
Author(s):  
Ricardo S. Ramiro ◽  
João Alpedrinha ◽  
Lucy Carter ◽  
Andy Gardner ◽  
Sarah E. Reece
Keyword(s):  
Sexual Reproduction ◽  
Innate Immune ◽  
Malaria Parasites ◽  
Immune Factors

Mathematical modeling and analysis of innate and humoral immune responses to dengue infections

2019 ◽  
Vol 12 (07) ◽  
pp. 1950077 ◽  
Author(s):  
Sulanie Perera ◽  
S. S. N. Perera
Keyword(s):  
Immune Response ◽  
Innate Immunity ◽  
Steady State ◽  
Immune Responses ◽  
Dengue Virus ◽  
Innate Immune ◽  
Virus Dynamics ◽  
Quasi Steady State ◽  
Humoral Immune ◽  
Humoral Immune Responses

Dengue is an acute arthropode-borne virus, belonging to the family Flaviviridae. Currently, there are no vaccines or treatments available against dengue. Thus it is important to understand the dynamics of dengue in order to control the infection. In this paper, we study the long-term dynamics of the model that is presented in [S. D. Perera and S. S. N. Perera, Simulation model for dynamics of dengue with innate and humoral immune responses, Comput. Math. Methods Med. 2018 (2018) 8798057, 18 pp. https://doi.org/10.1155/2018/8798057 ] which describes the interaction of virus with infected and uninfected cells in the presence of innate and humoral immune responses. It was found the model has three equilibria, namely: infection free equilibrium, no immune equilibrium and endemic equilibrium, then analyzed its stability analytically. The analytical findings of each model have been exemplified by numerical simulations. Given the fact that intensity of dengue virus replication at early times of infection could determine clinical outcomes, it is important to understand the impact of innate immunity, which is believed to be the first line of defense against an invading pathogen. For this we carry out a simulation case study to investigate the importance of innate immune response on dengue virus dynamics. A comparison was done assuming that innate immunity was active; innate immunity was in quasi-steady state and innate immunity was inactive during the virus replication process. By a further analysis of the qualitative behavior of the quasi-steady state, it was observed that innate immune response plays a pivotal role in dengue virus dynamics. It can change the dynamical behavior of the system and is essential for the virus clearance.

Robust dengue virus infection in bat cells and limited innate immune responses coupled with positive serology from bats in IndoMalaya and Australasia

2019 ◽  
Vol 77 (8) ◽  
pp. 1607-1622 ◽  
Author(s):  
Aaron T. Irving ◽  
Pritisha Rozario ◽  
Pui-San Kong ◽  
Katarina Luko ◽  
Jeffrey J. Gorman ◽  
...  
Keyword(s):  
Virus Infection ◽  
Immune Responses ◽  
Dengue Virus ◽  
Innate Immune ◽  
Innate Immune Responses ◽  
Positive Serology ◽  
Dengue Virus Infection

scholarly journals Effects of Acanthopanax senticosus supplementation on innate immunity and changes of related immune factors in healthy mice

2020 ◽  
pp. 175342592095520
Author(s):  
YunQiang Zhang ◽  
YunLu Zhang ◽  
ZiKui Liu
Keyword(s):  
Innate Immunity ◽  
Growth Performance ◽  
Innate Immune ◽  
Secretory Iga ◽  
Mouse Serum ◽  
Control Group ◽  
Dependent Manner ◽  
Acanthopanax Senticosus ◽  
Significant Difference ◽  
Immune Factors

Modern scientific research has shown that Acanthopanax senticosus (AS) can regulate the innate immunity of healthy animals, thus affecting the health of animals. However, there are few systematic reports on the changes of innate immune indices of healthy animals after consuming AS. The purpose of this project was to study the effect on healthy mice’s innate immunity and changes of related immune factors induced by feeding AS root powder supplementation. The results showed that the killing rate of natural cells increased in a dose-dependent manner in a certain time period. Compared to the control group, the treatment groups (T1, T2 and T3) improved significantly in the innate immune index (lysozyme, β-defensin-2 and duodenal secretory IgA (SIgA) to varying degrees) and induced corresponding changes of immune factors at certain time periods. The correlation between SIgA and IFN-γ in mouse serum was enhanced, and the higher the concentration of AS in the diet, the stronger the correlation was. However, there was no significant difference in growth performance among groups. It is proved that AS supplementation can enhance innate immunity and change several relevant immune factors and cells of healthy mice without affecting growth performance.

scholarly journals Increased Expression on Innate Immune Factors in Placentas From HIV-Infected Mothers Concurs With Dampened Systemic Immune Activation

2020 ◽  
Vol 11 ◽  
Author(s):  
Nátalli Zanete Pereira ◽  
Anna Cláudia Calvielli Castelo Branco ◽  
Kelly Cristina Gomes Manfrere ◽  
Josenilson Feitosa de Lima ◽  
Fabio Seiti Yamada Yoshikawa ◽  
...  
Keyword(s):  
Immune Activation ◽  
Innate Immune ◽  
Systemic Immune Activation ◽  
Immune Factors
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