The Partly Molar Pregnancy that is Not a Partial Mole

2005 ◽  
Vol 8 (2) ◽  
pp. 146-147 ◽  
Author(s):  
Harshwardhan M. Thaker
Keyword(s):  
Molar Pregnancy ◽  
Partial Mole

scholarly journals Partial molar pregnancy with live fetus in first trimester: what should we do next

2020 ◽  
Vol 20 (2) ◽  
Author(s):  
Eric Edwin ◽  
Uki Retno Budihastuti ◽  
Cut Sheira Elnita
Keyword(s):  
Hydatidiform Mole ◽  
First Trimester ◽  
Postnatal Period ◽  
Molar Pregnancy ◽  
Antenatal Consultation ◽  
Partial Mole ◽  
Close Observation ◽  
Live Fetus ◽  
Multiple Cysts

Abstract. The incidence of a normal live fetus with a partial mole is extremely rare, and it varies between 5 per 100000 and 1 per 10000 of the pregnancies. A partial molar pregnancy is a variation of a molar pregnancy in which an embryo either develops incompletely or with multiple structural anomalies.A 27-year-old Primigravide at 13 weeks of gestation got admitted with spotting per vaginam, excessive nausea and vomiting, and her ultrasound revealed a hydropic placenta with multiple cysts with a live fetus. Regarding these findings, the patient continued her pregnancy under close observation, and advanced sonographic evaluations were done to rule out other differentials. Ultrasonography found mosaicism in the partial mole (mostly diploid, a small part is triploid). In this condition, the prognosis condition for the fetus to be born safely is still probable. Ethics committee meetings are held with the consideration of the fetus's condition, whether monitoring is carried out regularly, and terminating the pregnancy in case of fetal emergency.The optimal management of hydatidiform mole with the coexistent live fetus is currently uncertain. Antenatal consultation should include a detailed discussion of maternal and fetal risks. It is also necessary to have close follow-up and evaluation of the patient's condition during the antenatal and postnatal period. Keywords: first trimester, live fetus , management, partial molar pregnancy

scholarly journals Ectopic tubal pregnancy with partial mole: a rare case

2018 ◽  
Vol 7 (4) ◽  
pp. 1651
Author(s):  
Nanda Patil ◽  
Robina Mohamed Nazeer ◽  
Jyoti Tele
Keyword(s):  
Fallopian Tube ◽  
Gold Standard ◽  
Rare Case ◽  
Clinicopathological Features ◽  
Histopathological Study ◽  
Molar Pregnancy ◽  
Abnormal Fertilization ◽  
Partial Mole ◽  
Placental Villi ◽  
Hydatidiform Moles

Hydatidiform moles are abnormal gestations characterised by the presence of hydropic changes in the placental villi associated with circumferential trophoblastic proliferation. They arise due to abnormal fertilization. Molar gestation commonly develops within the uterus but presence of molar changes in ectopic pregnancy is extremely rare. Author present a rare case of ectopic molar pregnancy in fallopian tube in a 20 years old female patient to highlight its clinicopathological features. Ectopic molar pregnancy in a fallopian tube is very rare and histopathological study is the gold standard for the exact diagnosis and further management. 

scholarly journals PRENATAL DIAGNOSIS AND POSTNATAL MANAGEMENT OF THE COMPLETE MOLAR PREGNANCY WITH COEXISTING NORMAL FETUS

2021 ◽  
pp. 26-27
Author(s):  
A . Nagarani ◽  
Dantam Hymavathi Devi
Keyword(s):  
Prenatal Diagnosis ◽  
Preterm Delivery ◽  
Hydatidiform Mole ◽  
Molar Pregnancy ◽  
Postnatal Management ◽  
Normal Fetus ◽  
Rare Phenomenon ◽  
Complete Mole ◽  
Partial Mole

Hydatidiform mole with a coexisting fetus is an extremely rare phenomenon; the incidence of such an occurrence ranges from 1 in 10 000 to 1 in 100000 gestations(Cunningham et al., 1997).There were two possible conditions:a partial mole with an abnormaltriploid fetus, and a complete mole combined with a normal fetus and placenta. Most cases suffer severe complications, such as pre-eclampsia, abortion and preterm delivery,or termination immediately after the diagnosis.

scholarly journals When a vesicular placenta meets a live fetus: case report of twin pregnancy with a partial hydatidiform mole

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Minhuan Lin ◽  
Jinzhu Chen ◽  
Bing Liao ◽  
Zhiming He ◽  
Shaobin Lin ◽  
...  
Keyword(s):  
Twin Pregnancy ◽  
Hydatidiform Mole ◽  
First Trimester ◽  
Molar Pregnancy ◽  
Amniotic Cavity ◽  
Individualized Care ◽  
Partial Mole ◽  
Live Fetus ◽  
Hydatidiform Moles

Abstract Background Hydatidiform moles exhibit a distinctive gross appearance of multiple vesicles in the placenta. The advances in cytogenetic technologies have helped uncover novel entities of hydatidiform moles and enabled elaborate diagnoses. However, management of a vesicular placenta with a coexistent live fetus poses a bigger challenge beyond hydatidiform moles. Case presentation A 33-year-old woman was referred to our department for suspected hydatidiform mole coexistent with a live fetus at 24 weeks’ gestation. The patient had conceived through double embryo transplantation, and first-trimester ultrasonography displayed a single sac. Mid-trimester imaging findings of normal placenta parenchyma admixed with multiple vesicles and a single amniotic cavity with a fetus led to suspicion of a singleton partial molar pregnancy. After confirmation of a normal diploid by amniocentesis and close surveillance, the patient delivered a healthy neonate. Preliminary microscopic examination of the placenta failed to clarify the diagnosis until fluorescence in situ hybridization showed a majority of XXY sex chromosomes. The patient developed suspected choriocarcinoma and achieved remission for 5 months after chemotherapy, but relapsed with suspected intermediate trophoblastic tumor. Conclusion We report a rare case of twin pregnancy comprising a partial mole and a normal fetus that resembled a singleton partial molar pregnancy. Individualized care is important in conditions where a vesicular placenta coexists with a fetus. We strongly recommend ancillary examinations in addition to traditional morphologic assessment in such cases.

Women With a Partial Mole During Their First Pregnancy and Diagnosed Earlier in Gestation Are at Increased Risk of Developing Gestational Trophoblastic Neoplasia

2014 ◽  
Vol 24 (5) ◽  
pp. 941-945 ◽  
Author(s):  
Michael J. Worley ◽  
Naima T. Joseph ◽  
Ross S. Berkowitz ◽  
Donald P. Goldstein
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Molar Pregnancy ◽  
Gestational Trophoblastic Neoplasia ◽  
First Line ◽  
Factors Associated ◽  
Increased Risk ◽  
Partial Mole ◽  
Significant Difference ◽  
History Of

ObjectiveThe aim of this study is to identify factors associated with gestational trophoblastic neoplasia (GTN) after partial molar pregnancy.MethodsWe retrospectively evaluated clinical data from 111 patients with a partial molar pregnancy between 1995 and 2010.ResultsA total of 111 patients with a partial molar pregnancy were available for analysis. There was no significant difference between patients who did and did not develop GTN with respect to patient age, parity, history of prior molar pregnancy, presenting signs/symptoms, uterine size greater than gestational age, clinical diagnosis, preevacuation sonogram findings, or the preevacuation human chorionic gonadotropin value. Patients who developed GTN had fewer prior pregnancies (median, 2 vs 3; P = 0.02) and were more likely to have had a partial molar pregnancy as their first gestational event (37.1% vs 17.1%; P = 0.03). Among the 35 patients who developed GTN, the median time to diagnosis of GTN was 47 days (range, 25–119 days), and the median human chorionic gonadotropin value at the time of GTN diagnosis was 475 mIU/mL (range, 20–52,630 mIU/mL). All women (100%) who developed GTN had stage I disease, and all patients (100%) had low-risk GTN. All 35 women (100%) were able to achieve remission, and most (85.7%) of these patients received methotrexate as first-line chemotherapy.ConclusionsWomen with a partial molar pregnancy as their first gestational event and diagnosed earlier in gestation are more likely to develop postmolar GTN.

THE RISK FACTORS OF MOLAR PREGNANCY

2017 ◽  
pp. 53-58
Author(s):  
Lam Huong Le
Keyword(s):  
High Risk ◽  
Gestational Trophoblastic Disease ◽  
Living Standard ◽  
Control Group ◽  
Uterine Perforation ◽  
Molar Pregnancy ◽  
Health It ◽  
Pregnancy Risk ◽  
History Of ◽  
And Control

Objectives: Molar pregnancy is the gestational trophoblastic disease and impact on the women’s health. It has several complications such as toxicity, infection, bleeding. Molar pregnancy also has high risk of choriocarcinoma which can be dead. Aim: To assess the risks of molar pregnancy. Materials and Methods: The case control study included 76 molar pregnancies and 228 pregnancies in control group at Hue Central Hospital. Results: The average age was 32.7 ± 6.7, the miximum age was 17 years old and the maximum was 46 years old. The history of abortion, miscarriage in molar group and control group acounted for 10.5% and 3.9% respectively, with the risk was higher 2.8 times; 95% CI = 1.1-7.7 (p<0.05). The history of molar pregnancy in molar pregnancy group was 9.2% and the molar pregnancy risk was 11.4 times higher than control group (95% CI = 2.3-56.4). The women having ≥ 4 times births accounted for 7.9% in molar group and 2.2% in control group, with the risk was higher 3.8 times, 95% CI= 1.1-12.9 (p<0.05). The molar risk of women < 20 and >40 years old in molar groups had 2.4 times higher than (95% CI = 1.1 to 5.2)h than control group. Low living standard was 7.9% in molar group and 1.3% in the control group with OR= 6.2; 95% CI= 1.5-25.6. Curettage twice accounted for 87.5%, there were 16 case need to curettage three times. There was no case of uterine perforation and infection after curettage. Conclusion: The high risk molar pregnancy women need a better management. Pregnant women should be antenatal cared regularly to dectect early molar pregnancy. It is nessecery to monitor and avoid the dangerous complications occuring during the pregnancy. Key words: Molar pregnancy, pregnancy women

scholarly journals Choriocarcinoma with uterine rupture presenting as acute haemoperitoneum and shock

2017 ◽  
Vol 6 (3) ◽  
pp. 1141 ◽  
Author(s):  
Mamour Gueye ◽  
Mame Diarra Ndiaye Gueye ◽  
Ousmane Thiam ◽  
Youssou Toure ◽  
Mor Cisse ◽  
...  
Keyword(s):  
Young Woman ◽  
Uterine Rupture ◽  
Gestational Trophoblastic Disease ◽  
Uterine Perforation ◽  
Molar Pregnancy ◽  
Rare Neoplasm ◽  
Trophoblastic Disease ◽  
Intraperitoneal Bleeding ◽  
Invasive Mole

Choriocarcinoma is a rare neoplasm and a malignant form of gestational trophoblastic disease. Invasive mole may perforate uterus through the myometrium resulting in uterine perforation and intraperitoneal bleeding. But uterine perforation due to choriocarcinoma is rare. We present a case of a young woman who presented 1 year after uterine evacuation of a molar pregnancy with invasive choriocarcinoma complicated by a uterine rupture and haemoperitoneum.

Normalisation of human chorionic gonadotrophin (hCG) levels in a patient with partial molar pregnancy with a uterine mass without chemotherapy: impact of using herbal remedies

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Norzila Ismail ◽  
Aida Maziha Zainudin ◽  
Gan Siew Hua
Keyword(s):  
Hydatidiform Mole ◽  
Abdominal Ultrasound ◽  
Massive Bleeding ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Herbal Remedies ◽  
Lung Field ◽  
Molar Pregnancy ◽  
Brucea Javanica

Abstract Objectives Level of βhCG and the presence of any uterine mass of hydatidiform mole need a careful review or monitoring in order to prevent metastasis, provide an early treatment and avoid unnecessary chemotherapy. Case presentation A 36-year old fifth gravida patient who had a missed abortion was diagnosed as having a molar pregnancy with beta human chorionic gonadotrophin (βhCG) level of 509,921 IU/L. Her lung field was clear and she underwent suction and curettage (S & C) procedure. However, after six weeks, AA presented to the emergency department with a massive bleeding, although her βhCG level had decreased to 65,770 IU/L. A trans-abdominal ultrasound indicated the presence of an intra-uterine mass (3.0 × 4.4 cm). Nevertheless, her βhCG continued to show a declining trend (8,426 IU/L). AA was advised to undergo a chemotherapy but she refused, citing preference for alternative medicine like herbs instead. She opted for an “at own risk” (AOR) discharge with scheduled follow up. Subsequently, her condition improved with her βhCG showing a downward trend. Surprisingly, at six months post S & C, her βhCG ameliorated to 0 IU/L with no mass detected by ultrasound. Conclusions Brucea javanica fruits, Pereskia bleo and Annona muricata leaves can potentially be useful alternatives to chemotherapy and need further studies.

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