Gadolinium (III) oxide nanoparticles coated with folic acid-functionalized poly(β-cyclodextrin-co-pentetic acid) as a biocompatible targeted nano-contrast agent for cancer diagnostic: in vitro and in vivo studies

2019 ◽  
Vol 32 (4) ◽  
pp. 487-500 ◽  
Author(s):  
Tohid Mortezazadeh ◽  
Elham Gholibegloo ◽  
Nader Riyahi Alam ◽  
Sadegh Dehghani ◽  
Soheila Haghgoo ◽  
...  
Keyword(s):  
Folic Acid ◽  
Contrast Agent ◽  
In Vivo Studies ◽  
Oxide Nanoparticles ◽  
Cancer Diagnostic

Synthesis, characterization, in vitro and in vivo studies of dextrin-coated zinc-iron ferrite nanoparticles (Zn0.5Fe0.5Fe2O4) as contrast agent in MRI

2015 ◽  
Vol 120 (3) ◽  
pp. 1189-1196 ◽  
Author(s):  
T. Zare ◽  
M. Lotfi ◽  
H. Heli ◽  
N. Azarpira ◽  
A. R. Mehdizadeh ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Ferrite Nanoparticles ◽  
In Vivo Studies ◽  
Iron Ferrite

Folic acid modified copper oxide nanoparticles for targeted delivery in in vitro and in vivo systems

RSC Advances ◽  
2015 ◽  
Vol 5 (83) ◽  
pp. 68169-68178 ◽  
Author(s):  
Dipranjan Laha ◽  
Arindam Pramanik ◽  
Sourav Chattopadhyay ◽  
Sandip kumar Dash ◽  
Somenath Roy ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Folic Acid ◽  
Cancer Therapy ◽  
Copper Oxide ◽  
Targeted Delivery ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Breast Cancer Therapy

Targeted delivery of copper oxide nanoparticles for breast cancer therapy.

scholarly journals An iron-based T 1 contrast agent made of iron-phosphate complexes: In vitro and in vivo studies

2007 ◽  
Vol 20 (1) ◽  
pp. 27-37 ◽  
Author(s):  
Elisenda Rodríguez ◽  
Rui V. Simoes ◽  
Anna Roig ◽  
Elies Molins ◽  
Nataliya Nedelko ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Iron Phosphate ◽  
In Vivo Studies ◽  
Iron Based

Development of a Dendritic Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) Contrast Agent: Synthesis, Toxicity (in Vitro) and Relaxivity (in Vitro, in Vivo) Studies

2009 ◽  
Vol 20 (4) ◽  
pp. 760-767 ◽  
Author(s):  
Annabelle Bertin ◽  
Jérôme Steibel ◽  
Anne-Isabelle Michou-Gallani ◽  
Jean-Louis Gallani ◽  
Delphine Felder-Flesch
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
In Vivo Studies ◽  
Resonance Imaging ◽  
Toxicity In Vitro

scholarly journals PREPARATION AND EVALUATION OF IRON OXIDE NANOPARTICLES FOR TREATMENT OF IRON DEFICIENCY ANEMIA

2018 ◽  
Vol 10 (1) ◽  
pp. 142 ◽  
Author(s):  
Fahima Hashem ◽  
Mohamed Nasr ◽  
Yomna Ahmed
Keyword(s):  
Folic Acid ◽  
Iron Oxide ◽  
Iron Deficiency ◽  
Iron Oxide Nanoparticles ◽  
Deficiency Anemia ◽  
Oxide Nanoparticles ◽  
Prepared Nanoparticles ◽  
Commercial Iron

Objective: The objective of this research was to formulate and evaluate iron oxide nanoparticles for treatment of iron deficiency anemia (IDA).Methods: Iron oxide nanoparticles were prepared by co-precipitation method and stabilized by coating with folic acid or chitosan. The prepared nanoparticles were characterized in vitro for morphology, particle size, zeta potential, crystallinity and ultraviolet-visible (UV-Vis) absorption. In vivo studies were performed to evaluate the efficacy of the prepared nanoparticles in treating iron-deficient anemic rats compared to the commercial iron product.Results: In vitro results revealed that particle sizes were 65.95±5 nm, 220.2±12 nm and 295.3±19 nm for uncoated iron oxide nanoparticles, folic acid-coated iron oxide nanoparticles and chitosan coated iron oxide nanoparticles, respectively. UV-Vis absorption spectrum and x-ray diffraction (XRD) patterns confirmed that the prepared nanoparticles were iron oxide nanoparticles. In vivo results indicated that folic acid-coated iron oxide nanoparticles showed effective restorative action, returning haemoglobin (Hb) concentration to normal levels, where not only complete recovery of Hb within short time from the anemic state to the high normal level, but also improved Hb concentrations compared to the commercial iron product.Conclusion: The results obtained in this research work clearly indicated a promising potential of folic acid-coated iron oxide nanoparticles for the effective treatment of IDA.

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