Immobilization of Metal–Organic Frameworks on Supports for Sample Preparation and Chromatographic Separation

This review summarizes the recent advances concerning metal–organic frameworks (MOFs) modified with several biomolecules (e.g., amino acids, nucleobases, proteins, antibodies, aptamers, etc.) as ligands to prepare affinity-based sorbents for application in the sample preparation field. The preparation and incorporation strategies of these MOF-based affinity materials were described. Additionally, the different types of ligands that can be employed for the synthesis of these biocomposites and their application as sorbents for the selective extraction of molecules and clean-up of complex real samples is reported. The most important features of the developed biocomposites will be discussed throughout the text in different sections, and several examples will be also commented on in detail.

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Metal-organic frameworks as advanced sorbents in sample preparation for small organic analytes

Coordination Chemistry Reviews ◽

10.1016/j.ccr.2019.06.014 ◽

2019 ◽

Vol 397 ◽

pp. 1-13 ◽

Cited By ~ 19

Author(s):

Xianjiang Li ◽

Wen Ma ◽

Hongmei Li ◽

Yu Bai ◽

Huwei Liu

Keyword(s):

Sample Preparation ◽

Metal Organic Frameworks ◽

Metal Organic ◽

Organic Analytes

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Evaluation of isostructural metal–organic frameworks coated capillary columns for the gas chromatographic separation of alkane isomers

Talanta ◽

10.1016/j.talanta.2012.07.063 ◽

2012 ◽

Vol 99 ◽

pp. 944-950 ◽

Cited By ~ 38

Author(s):

Lin Fan ◽

Xiu-Ping Yan

Keyword(s):

Chromatographic Separation ◽

Metal Organic Frameworks ◽

Capillary Columns ◽

Metal Organic ◽

Gas Chromatographic Separation

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Insights into chromatographic separation using core–shell metal–organic frameworks: Size exclusion and polarity effects

Journal of Chromatography A ◽

10.1016/j.chroma.2015.07.120 ◽

2015 ◽

Vol 1411 ◽

pp. 77-83 ◽

Cited By ~ 16

Author(s):

Weiwei Qin ◽

Martin E. Silvestre ◽

Frank Kirschhöfer ◽

Gerald Brenner-Weiss ◽

Matthias Franzreb

Keyword(s):

Chromatographic Separation ◽

Metal Organic Frameworks ◽

Size Exclusion ◽

Core Shell ◽

Metal Organic ◽

Polarity Effects

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Applications of Metal-Organic Frameworks in Food Sample Preparation

Molecules ◽

10.3390/molecules23112896 ◽

2018 ◽

Vol 23 (11) ◽

pp. 2896 ◽

Cited By ~ 15

Author(s):

Natalia Manousi ◽

George Zachariadis ◽

Eleni Deliyanni ◽

Victoria Samanidou

Keyword(s):

Sample Preparation ◽

High Surface ◽

Metal Organic Frameworks ◽

High Surface Area ◽

Food Samples ◽

Inorganic Materials ◽

Molecular Imprinted Polymers ◽

Metal Organic ◽

Food Matrices ◽

Carbon Based Nanomaterials

Food samples such as milk, beverages, meat and chicken products, fish, etc. are complex and demanding matrices. Various novel materials such as molecular imprinted polymers (MIPs), carbon-based nanomaterials carbon nanotubes, graphene oxide and metal-organic frameworks (MOFs) have been recently introduced in sample preparation to improve clean up as well as to achieve better recoveries, all complying with green analytical chemistry demands. Metal-organic frameworks are hybrid organic inorganic materials, which have been used for gas storage, separation, catalysis and drug delivery. The last few years MOFs have been used for sample preparation of pharmaceutical, environmental samples and food matrices. Due to their high surface area MOFs can be used as adsorbents for the development of sample preparation techniques of food matrices prior to their analysis with chromatographic and spectrometric techniques with great performance characteristics.

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