scholarly journals Feasibility and Acceptability of Real-Time Antiretroviral Adherence Monitoring among Depressed Women Living with HIV in the Deep South of the US

2018 ◽  
Vol 23 (5) ◽  
pp. 1306-1314 ◽  
Author(s):  
Kristi Lynn Stringer ◽  
Andres Azuero ◽  
Corilyn Ott ◽  
Christina Psaros ◽  
Christina H. Jagielski ◽  
...  
Keyword(s):  
Real Time ◽  
Deep South ◽  
Antiretroviral Adherence ◽  
Women Living With Hiv ◽  
The Us ◽  
Adherence Monitoring ◽  
Living With Hiv

scholarly journals Antiretroviral therapy self-management: Pilot study of an electronic medication event monitoring system among African-American women living with HIV in rural Florida (Preprint)

2019 ◽  
Author(s):  
Robert Lucero ◽  
Renessa Williams ◽  
Tanisia Esalomi ◽  
Paula Alexander-Delpech ◽  
Christa Cook ◽  
...  
Keyword(s):  
African American ◽  
Antiretroviral Therapy ◽  
Pilot Study ◽  
African American Women ◽  
Art Adherence ◽  
Event Monitoring ◽  
Women Living With Hiv ◽  
The Us ◽  
Rural Florida ◽  
Living With Hiv

BACKGROUND The human immunodeficiency virus (HIV) remains a significant health issue in the United States and disproportionately affects African Americans. African-American women living with HIV (AAWH) experience a particularly high number of barriers when attempting to manage their HIV care, including antiretroviral therapy (ART) adherence. To enable the development and assessment of effective interventions that address these barriers to support ART adherence, there is a critical need to understand more fully the use of objective measures of ART adherence among AAWH, including electronic medication dispensers for real-time surveillance. OBJECTIVE To evaluate the use of the Wisepill Medication Event Monitoring System (MEMS), and compare objective and subjective measures of ART adherence. METHODS We conducted a 30-day exploratory sequential mixed-methods pilot study of the MEMS among a convenience sample of community-dwelling AAWH (n=14) in rural Florida. AAWH were trained on the use of the MEMS to determine the feasibility of collecting, capturing, and manipulating the MEMS data for an objective measure of ART adherence. Self-report sociodemographic information, including a measure of antiretroviral therapy (ART) adherence, was also collected from AAWH. RESULTS We found that a majority of participants were successful at using the electronic MEMS. Daily use of the MEMS tended to be outside of the usual time participants took their medication. Three 30-day medication event patterns were found that characterized ART adherence, specifically uniformed and ununiformed medication adherence and ununiformed medication non-adherence. There were relatively few MEMS disruption among study participants. Overall, adjusted daily ART adherence was 81.08% and subjective ART adherence was 77.78%. CONCLUSIONS This pilot study on the use and evaluation of the Wisepill MEMS among AAWH in rural Florida is the first known in the US. The findings of this study are encouraging because ten out of twelve participants consistently used the MEMS, had relatively few MEMS, and objective adjusted daily and overall subjective ART adherence were very similar. Based findings from this study, we think researchers can be confident in using the Wisepill MEMS in future studies of AAWH and PLWH in the US after considering our practical suggestions. The following practical considerations are suggested when considering measuring objective medication adherence: (1) before using a MEMS be familiar with the targeted populations’ characteristics; (2) choose a MEMS that aligns with the participants’ day-to-day activities; (3) ensure the MEMS’ features and resulting data support the research goals; (4) assess the match between user’s ability, wireless features of the MEMS, and the geographic location of participants; and (5) considering the cost of MEMS and the research budget.

scholarly journals Perceptions of People Living with HIV and HIV Healthcare Providers on Real-Time Measuring and Monitoring of Antiretroviral Adherence Using Ingestible Sensors: A Qualitative Study

2020 ◽  
Vol 2020 ◽  
pp. 1-10 ◽  
Author(s):  
Susan Kamal ◽  
Marc I. Rosen ◽  
Christina Lazar ◽  
Lisa Siqueiros ◽  
Yan Wang ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Real Time ◽  
Health Care Providers ◽  
Thematic Analysis ◽  
People Living With Hiv ◽  
Care Providers ◽  
Convenience Sample ◽  
Antiretroviral Adherence ◽  
Advantages And Disadvantages ◽  
Living With Hiv

Objective. To describe and analyze the perception and attitudes of people living with HIV (PLWH) and HIV HCPs towards medication adherence with a focus on a digital medicine program (DMP) with ingestible sensors (ISs). Methods. This is a qualitative analysis pilot study of PLWH who were using DMP recruited by purposive sampling. A convenience sample of HCPs was interviewed. Semistructured interviews were conducted, and thematic analysis was performed. Results. Fifteen PLWH were interviewed, and thematic analysis resulted in three main themes: self-identified medication adherence patterns, experiences with the DMP, and recommending the DMP to others. Six health care providers (HCPs) described barriers and facilitators to adherence, as well as advantages and disadvantages of using or recommending the DMP to PLWH. Conclusion. This study evaluated participant and provider responses to DMP, which is a novel technology for real-time measuring and monitoring adherence with the IS. Participant and provider responses were mixed, highlighting both the advantages and limitations of the technology. Practice Implications. Taking PLWH experiences into consideration will enhance the development of this and other useful tools that clinicians and researchers can use for enhanced patient care.

Substance Use, Violence, and Antiretroviral Adherence: A Latent Class Analysis of Women Living with HIV in Canada

2017 ◽  
Vol 22 (3) ◽  
pp. 971-985 ◽  
Author(s):  
Allison Carter ◽  
◽  
Eric Abella Roth ◽  
Erin Ding ◽  
M-J Milloy ◽  
...  
Keyword(s):  
Substance Use ◽  
Latent Class Analysis ◽  
Latent Class ◽  
Class Analysis ◽  
Antiretroviral Adherence ◽  
Women Living With Hiv ◽  
Living With Hiv

scholarly journals Correlates of antiretroviral adherence and viral load among transgender women living with HIV

AIDS Care ◽  
2014 ◽  
Vol 26 (8) ◽  
pp. 976-982 ◽  
Author(s):  
Jae M. Sevelius ◽  
Parya Saberi ◽  
Mallory O. Johnson
Keyword(s):  
Viral Load ◽  
Transgender Women ◽  
Antiretroviral Adherence ◽  
Women Living With Hiv ◽  
Living With Hiv

scholarly journals 2514. Real-time Antiretroviral Electronic Adherence Monitoring In Young African American Men Who Have Sex With Men

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S873-S873
Author(s):  
Mark S Dworkin ◽  
Palak Panchal ◽  
Antonio Jimenez ◽  
Robert Garofalo ◽  
Jessica Haberer ◽  
...  
Keyword(s):  
African American ◽  
Real Time ◽  
Electronic Monitoring ◽  
African American Men ◽  
Observation Time ◽  
Text Messages ◽  
Sex With Men ◽  
Adherence Monitoring ◽  
Living With Hiv

Abstract Background Antiretroviral therapy adherence remains a challenge, particularly for young African American men who have sex with men (YAAMSM). We enrolled 40 YAAMSM for 3 months of electronic adherence monitoring (EAM). These data may be useful in developing an antiretroviral EAM intervention that responds to missed doses with real-time text messages. Methods YAAMSM (age 18–34 years) living with HIV and taking ART participated in a quantitative and qualitative study that included ART adherence monitoring with a Wisepill electronic monitoring device for up to 3 months. Interviews were performed during April 2017–April 2019 at baseline and follow-up. Monitoring data were reviewed to determine timing and patterns of missing their first true adjudicated miss for durations of 1 dose, 3 consecutive days, and 7 consecutive days. Follow-up qualitative interviews included exploring acceptability of monitoring. Results The median age was 28 years and median participant observation time was 90 days (interquartile range 88–90 days) (n = 40 participants). Among those with at least 2 weeks follow-up and adjudication (n = 32), 100% missed at least 1 day. Most (82%) of these participants were <80% adherent in at least one of their monitored months. One dose and 3-day misses did not cluster (e.g., no disproportion on weekends). Most (88%) first missed doses occurred during the first 9 days monitored and most (69%) of the 13 who missed 3 consecutive days missed within the first monitored month. Four participants missed 7 consecutive days. Among 31 with a follow-up interview, 28 (90%) felt receiving a text because of device monitoring would affect their medication taking in the future. Illustrative quotes included, “It made me more responsible” and “…it makes you want to do it right.” Conclusion Most YAAMSM living with HIV in this study had adherence below the target threshold of >80%. These data support development of a text message responsive real-time electronic adherence monitoring intervention approach. Disclosures All authors: No reported disclosures.

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