Dynamics of a Nonlocal Dispersal Foot-and-Mouth Disease Model in a Spatially Heterogeneous Environment

2021 ◽  
Vol 41 (2) ◽  
pp. 552-572
Author(s):  
Xiaoyan Wang ◽  
Junyuan Yang
Keyword(s):  
Disease Model ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Heterogeneous Environment ◽  
Nonlocal Dispersal ◽  
Foot And Mouth

Dynamical analysis of a fractional-order foot-and-mouth disease model

2021 ◽  
Vol 15 (1) ◽  
pp. 65-82
Author(s):  
Tinashe B. Gashirai ◽  
Senelani D. Hove-Musekwa ◽  
Steady Mushayabasa
Keyword(s):  
Fractional Order ◽  
Disease Model ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Dynamical Analysis ◽  
Foot And Mouth

scholarly journals Post-outbreak surveillance strategies to support proof of freedom from foot-and-mouth disease

2021 ◽  
Author(s):  
Richard Bradhurst ◽  
Graeme Garner ◽  
Iain East ◽  
Clare Death ◽  
Aaron Dodd ◽  
...  
Keyword(s):  
Disease Model ◽  
Foot And Mouth Disease ◽  
Control Program ◽  
Mouth Disease ◽  
Surveillance Program ◽  
Statistical Confidence ◽  
Foot And Mouth ◽  
The Face ◽  
Sampling Regime ◽  
The Cost

AbstractWhilst emergency vaccination may help contain foot-and-mouth disease in a previously FMD-free country, its use complicates post-outbreak surveillance and the recovery of FMD-free status. A structured surveillance program is required that can distinguish between vaccinated and residually infected animals, and provide statistical confidence that the virus is no longer circulating in previously infected areas.Epidemiological models have been well-used to investigate the potential benefits of emergency vaccination during a control progam and when/where/whom to vaccinate in the face of finite supplies of vaccine and personnel. Less well studied are post-outbreak issues such as the management of vaccinated animals and the implications of having used vaccination during surveillance regimes to support proof-of-freedom. This paper presents enhancements to the Australian Animal Disease Model (AADIS) that allow comparisons of different post-outbreak surveillance sampling regimes for establishing proof-of-freedom from FMD.A case study is provided that compares a baseline surveillance sampling regime (derived from current OIE guidelines), with an alternative less intensive sampling regime. It was found that when vaccination was not part of the control program, a reduced sampling intensity significantly reduced the number of samples collected and the cost of the post-outbreak surveillance program, without increasing the risk of missing residual infected herds.

scholarly journals Airborne spread of foot-and-mouth disease – Model intercomparison

2010 ◽  
Vol 183 (3) ◽  
pp. 278-286 ◽  
Author(s):  
John Gloster ◽  
Andrew Jones ◽  
Alison Redington ◽  
Laura Burgin ◽  
Jens H. Sørensen ◽  
...  
Keyword(s):  
Disease Model ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Model Intercomparison ◽  
Foot And Mouth

Foot and mouth disease model verification and ‘relative validation’ through a formal model comparison

2011 ◽  
Vol 30 (2) ◽  
pp. 527-540 ◽  
Author(s):  
R.L. SANSON ◽  
N. HARVEY ◽  
M.G. GARNER ◽  
M.A. STEVENSON ◽  
T.M. DAVIES ◽  
...  
Keyword(s):  
Model Comparison ◽  
Formal Model ◽  
Disease Model ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Model Verification ◽  
Foot And Mouth

scholarly journals Lyapunov Stability Analysis of a Delayed Foot-and-Mouth Disease Model with Animal Vaccination

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Tinashe B. Gashirai ◽  
Senelani D. Hove-Musekwa ◽  
Steady Mushayabasa
Keyword(s):  
Disease Virus ◽  
Disease Model ◽  
Intervention Strategy ◽  
Ecological Factors ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Sub Saharan Africa ◽  
Epidemic Dynamics ◽  
Mouth Disease Virus ◽  
Foot And Mouth

Foot-and-mouth disease virus remains one of the most important livestock diseases in sub-Saharan Africa and several Southeast Asian countries. Vaccination of livestock has been recognized as an important tool for the control of foot-and-mouth disease virus. However, this intervention strategy has some limitations. Generally, vaccine production is a complex multistep process which involves development, manufacturing, and delivery processes, and through this extensive process, some challenges such as poor vaccine storage often arise. More often, these challenges alter the validity of the vaccination. Foot-and-mouth disease virus epidemic dynamics have been extensively explored, but understanding the role of vaccination validity on virus endemicity is lacking. We present a time-delayed foot-and-mouth disease model that incorporates relevant biological and ecological factors, vaccination effects, and disease carriers. We determined the basic reproduction number and demonstrated that it is an important metric for persistence and extinction of the disease in the community. Numerical illustrations were utilised to support some of the analytical results.

Biophysical Measurement of Molecular Weight of Foot-and-Mouth Disease RNA Fragments

1974 ◽  
Vol 32 ◽  
pp. 262-263
Author(s):  
Sydney S. Breese ◽  
Howard L. Bachrach
Keyword(s):  
Chemical Properties ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Distilled Water ◽  
Bovine Plasma ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Carbon Coated ◽  
Rna Fragments ◽  
Physical And Chemical

Continuing studies on the physical and chemical properties of foot-and-mouth disease virus (FMDV) have included electron microscopy of RNA strands released when highly purified virus (1) was dialyzed against demlneralized distilled water. The RNA strands were dried on formvar-carbon coated electron microscope screens pretreated with 0.1% bovine plasma albumin in distilled water. At this low salt concentration the RNA strands were extended and were stained with 1% phosphotungstic acid. Random dispersions of strands were recorded on electron micrographs, enlarged to 30,000 or 40,000 X and the lengths measured with a map-measuring wheel. Figure 1 is a typical micrograph and Fig. 2 shows the distributions of strand lengths for the three major types of FMDV (A119 of 6/9/72; C3-Rezende of 1/5/73; and O1-Brugge of 8/24/73.

High resolution surface structure of foot-and-mouth disease virus

1978 ◽  
Vol 36 (2) ◽  
pp. 376-377
Author(s):  
S. S. Breese ◽  
H. L. Bachrach
Keyword(s):  
Electron Microscopy ◽  
High Resolution ◽  
Surface Structure ◽  
Disease Virus ◽  
Potassium Phosphate ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Physical Measurements ◽  
Mouth Disease Virus ◽  
Foot And Mouth

Models for the structure of foot-and-mouth disease virus (FMDV) have been proposed from chemical and physical measurements (Brown, et al., 1970; Talbot and Brown, 1972; Strohmaier and Adam, 1976) and from rotational image-enhancement electron microscopy (Breese, et al., 1965). In this report we examine the surface structure of FMDV particles by high resolution electron microscopy and compare it with that of particles in which the outermost capsid protein VP3 (ca. 30, 000 daltons) has been split into smaller segments, two of which VP3a and VP3b have molecular weights of about 15, 000 daltons (Bachrach, et al., 1975).Highly purified and concentrated type A12, strain 119 FMDV (5 mg/ml) was prepared as previously described (Bachrach, et al., 1964) and stored at 4°C in 0. 2 M KC1-0. 5 M potassium phosphate buffer at pH 7. 5. For electron microscopy, 1. 0 ml samples of purified virus and trypsin-treated virus were dialyzed at 4°C against 0. 2 M NH4OAC at pH 7. 3, deposited onto carbonized formvar-coated copper screens and stained with phosphotungstic acid, pH 7. 3.

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