Selection of Parameters for Filtering Distal Arterial Pulse Signal Using Multi-Resolution Wavelet Transforms

2013 ◽  
Vol 47 (3) ◽  
pp. 146-149 ◽  
Author(s):  
A. A. Fedotov
Author(s):  
Md Mahfuzur Rahman ◽  
Najmin Ara Sultana ◽  
Linda Vahala ◽  
Leryn Reynolds ◽  
Zhili Hao

Abstract With the goal of achieving consistence in interpretation of an arterial pulse signal between its vibration model and its hemodynamic relations and improving its physiological implications in our previous study, this paper presents an improved vibration-model-based analysis for estimation of arterial parameters: elasticity (E), viscosity (η), and radius (r0) at diastolic blood pressure (DBP) of the arterial wall, from a noninvasively measured arterial pulse signal. The arterial wall is modeled as a unit-mass vibration model, and its spring stiffness (K) and damping coefficient (D) are related to arterial parameters. Key features of a measured pulse signal and its first-order and second-order derivatives are utilized to estimate the values of K and D. These key features are then utilized in hemodynamic relations, where their interpretation is consistent with the vibration model, to estimate the value of r0 from K and D. Consequently, E, η, and pulse wave velocity (PWV) are also estimated from K and D. The improved vibration-model-based analysis was conducted on pulse signals of a few healthy subjects measured under two conditions: at-rest and immediately post-exercise. With E, r0, and PWV at-rest as baseline, their changes immediately post-exercise were found to be consistent with the related findings in the literature. Thus, this improved vibration-model-based analysis is validated and contributes to estimation of arterial parameters with better physiological implications, as compared with its previous counterpart.


Author(s):  
Dan Wang ◽  
Leryn Reynolds ◽  
Thomas Alberts ◽  
Linda Vahala ◽  
Zhili Hao

Abstract This paper presents three technical issues associated with arterial pulse signal measurements using a microfluidic-based tactile sensor: motion artifact, overlying tissue at an artery and inter-subject variation. Arising from the sensor-artery interaction upon hold-down pressure on the sensor, a measured pulse signal is a combination of the sensor design, hold-down pressure, overlying tissue at an artery, the arterial wall and the true pulse signal in the artery. Meanwhile, motion artifact causes change in the sensor-artery interaction and also plays a non-negligible role in a measured pulse signal. The influence of motion artifact on a measured pulse signal can be reduced by a sensor with high stiffness. To obtain a pulse signal at near-zero transmural pressure with reasonable accuracy, matching the sensor design with the overlying tissue at an artery is critical for achieving good conformity of the sensor to the artery (for signal transmission) with minimal distortion of the true one in the artery. For simplicity, a uniform layer is utilized to adjust the sensor design. While a uniform layer added to a sensor improves its conformity with the radial artery (RA) embedded deep under the skin, a uniform layer is also needed as a cushion to reduce suppression of the true pulse signal at the superficial temporal artery (STA) near the skin. Due to inter-subject variation (i.e, overlying tissue and artery size), the absolute values of arterial indices derived from a measured pulse signal at the same artery are not comparable between subjects. Post-exercise recovery of arterial indices derived from measured pulse signals is suggested to serve as a better assessment of the cardiovascular (CV) system.


2016 ◽  
Author(s):  
Sara Casaccia ◽  
Erik J. Sirevaag ◽  
Edward J. Richter ◽  
Luigi Casacanditella ◽  
Lorenzo Scalise ◽  
...  

2021 ◽  
Author(s):  
Roman Carlo Roxas ◽  
Erika Osbourne ◽  
Dylon Johnson ◽  
Joshua Wolbert ◽  
Adam Harnish ◽  
...  

2013 ◽  
Vol 655-657 ◽  
pp. 705-709 ◽  
Author(s):  
Tian Li Li ◽  
Gang Xu ◽  
Li Cun Fang

The SAW delay-line sensor can obtain the energy of the RF pulse query signal through the wireless method. The RF pulse echo signal of the SAW delay-line sensor is significant effected by the different query pulse width of the RF pulse query signal, which is directly related to the sensor precision. The size of the IDT and reflectors, the distance between the IDT and reflector, and the distance among the different reflectors can affect the selection of the RF pulse query signal. The selection method of the query pulse width is discussed through the theoretical analysis and experimental analysis according to the SAW delay-line transmission characteristics. The query pulse width can be calculated directly through the design parameters of the SAW sensor.


Author(s):  
Dan Wang ◽  
Andrew Stamenkovich ◽  
Christian Zemlin ◽  
Zhili Hao

In light of the need to diagnose and monitor the heart condition of a heart failure patient, this paper presents a preliminary investigation on the application of a flexible microfluidic-based sensor for measuring the arterial pulse signal during the Valsalva Maneuver (VM), which allows assessment of the patient’s volume status. The core of the sensor is a polydimethylsiloxane (PDMS) microstructure embedded with a 5x1 electrolyte-enabled resistive transducer array. As a time-varying load, an arterial pulse signal acting on the microstructure gives rise to the distributed sensor deflection along the microstructure length and further registers as the resistance changes by the transducer array. The radial pulse signals of four healthy subjects during the VM are measured and are further expressed in terms of the absolute resistance and the sensor deflection. The pulse amplitude change in absolute resistance captures the expected hemodynamic response of a healthy subject to the VM, but the sensor deflection does not manifest such response, due to baseline drift. The corresponding pulse signals of the four subjects at-rest are also measured, verifying that the pulse amplitude change in absolute resistance does not arise from baseline drift. In the future, this sensor will be used to measure the arterial pulse signals of heart failure patients during the VM.


Author(s):  
Dan Wang ◽  
Frank A. Lattanzio ◽  
Mario C. Rodriguez ◽  
Zhili Hao

Abstract In this work, a microfluidic-based tactile sensor was investigated for monitoring changes in the cardiovascular (CV) system of a rabbit caused by phenylephrine. The sensor was fixed on the front right leg of an anesthetized rabbit to measure the arterial pulse signal. Phenylephrine, as a vasoconstrictor, was used to introduce CV changes of the rabbit. Two sensors, one with high sensitivity and the other with low sensitivity, were tested on their suitability for measuring the pulse signals of the rabbit. The sensor with low sensitivity generated clear pulse signals and was further used to monitor the CV changes of the rabbit caused by phenylephrine. An automated sphygmomanometer and an ECG were used to record blood pressure and heart rate for comparison. Three low-dose injections of phenylephrine were sequentially performed on the rabbit. Through model-based analysis of the measured pulse signals, arterial elastic modulus, arterial radius and pulse wave velocity (PWV) were obtained. As compared with the baseline values measured before injection, injections of phenylephrine caused an increase in mean blood pressure (MAP) recorded by the medical instruments, and a decrease in arterial radius (increase in peripheral vascular resistance (PVR)) and an increase in arterial elastic modulus and PWV captured by the tactile sensor. Thus, the tactile sensor was proven to be feasible for monitoring the changes in the CV system caused by phenylephrine.


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