scholarly journals A fish intestinal epithelial barrier model established from the rainbow trout (Oncorhynchus mykiss) cell line, RTgutGC

2017 ◽  
Vol 33 (6) ◽  
pp. 539-555 ◽  
Author(s):  
Matteo Minghetti ◽  
Carolin Drieschner ◽  
Nadine Bramaz ◽  
Hannah Schug ◽  
Kristin Schirmer
Keyword(s):  
Rainbow Trout ◽  
Oncorhynchus Mykiss ◽  
Cell Line ◽  
Epithelial Barrier ◽  
Intestinal Epithelial ◽  
Intestinal Epithelial Barrier ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
Barrier Model

The glial cell-line derived neurotrophic factor: a novel regulator of intestinal barrier function in health and disease

2016 ◽  
Vol 310 (11) ◽  
pp. G1118-G1123 ◽  
Author(s):  
Michael Meir ◽  
Sven Flemming ◽  
Natalie Burkard ◽  
Johanna Wagner ◽  
Christoph-Thomas Germer ◽  
...  
Keyword(s):  
Cell Line ◽  
Glial Cell ◽  
Neurotrophic Factor ◽  
Intestinal Barrier ◽  
Chronic Inflammatory Bowel Disease ◽  
Epithelial Barrier ◽  
Intestinal Epithelial ◽  
Intestinal Epithelial Barrier ◽  
Health And Disease ◽  
Inflammatory Bowel

Regulation of the intestinal epithelial barrier is a differentiated process, which is profoundly deranged in inflammatory bowel diseases. Recent data provide evidence that the glial cell line-derived neurotrophic factor (GDNF) is critically involved in intestinal epithelial wound healing and barrier maturation and exerts antiapoptotic effects under certain conditions. Furthermore, not only the enteric nervous system, but also enterocytes synthesize GDNF in significant amounts, which points to a potential para- or autocrine signaling loop between enterocytes. Apart from direct effects of GDNF on enterocytes, an immunomodulatory role of this protein has been previously assumed because of a significant reduction of inflammation in a model of chronic inflammatory bowel disease after application of GDNF. In this review we summarize the current knowledge of GDNF on intestinal epithelial barrier regulation and discuss the novel role for GDNF as a regulator of intestinal barrier functions in health and disease.

Development of a cell line from primary cultures of rainbow trout, Oncorhynchus mykiss (Walbaum), gills

1994 ◽  
Vol 17 (6) ◽  
pp. 601-611 ◽  
Author(s):  
N. C. BOLS ◽  
A. BARLIAN ◽  
M. CHIRINO-TREJO ◽  
S. J. CALDWELL ◽  
P. GOEGAN ◽  
...  
Keyword(s):  
Rainbow Trout ◽  
Oncorhynchus Mykiss ◽  
Cell Line ◽  
Primary Cultures ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
A Cell

Novel polyurethane-based nanoparticles of infliximab to reduce inflammation in an in-vitro intestinal epithelial barrier model

2019 ◽  
Vol 565 ◽  
pp. 533-542 ◽  
Author(s):  
Ritesh M. Pabari ◽  
Clara Mattu ◽  
Sailesh Partheeban ◽  
Aqeel Almarhoon ◽  
Monica Boffito ◽  
...  
Keyword(s):  
Epithelial Barrier ◽  
Intestinal Epithelial ◽  
Intestinal Epithelial Barrier ◽  
Barrier Model

scholarly journals A glyphosate-based herbicide induces sub-lethal effects in early life stages and liver cell line of rainbow trout, Oncorhynchus mykiss

2019 ◽  
Vol 216 ◽  
pp. 105291 ◽  
Author(s):  
Shannon Weeks Santos ◽  
Patrice Gonzalez ◽  
Bettie Cormier ◽  
Nicolas Mazzella ◽  
Bertille Bonnaud ◽  
...  
Keyword(s):  
Rainbow Trout ◽  
Oncorhynchus Mykiss ◽  
Cell Line ◽  
Liver Cell ◽  
Early Life ◽  
Life Stages ◽  
Early Life Stages ◽  
Lethal Effects ◽  
Liver Cell Line ◽  
Rainbow Trout Oncorhynchus Mykiss
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