scholarly journals Clinical application of the SurePath liquid-based Pap test in cytological screening of bronchial brushing for the diagnosis of lung cancer

2010 ◽  
Vol 62 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Yi-Bo Fan ◽  
Qing-Shan Wang ◽  
Lin Ye ◽  
Tian-Yu Wang ◽  
Guang-Ping Wu
Keyword(s):  
Lung Cancer ◽  
Clinical Application ◽  
Pap Test ◽  
Bronchial Brushing ◽  
Diagnosis Of Lung Cancer

Diagnostic role of liquid-based cytology of bronchial lavage fluid in addition to bronchial brushing specimens in lung cancer

2020 ◽  
pp. 030089162096021
Author(s):  
Chao Cao ◽  
Xuechan Yu ◽  
Tingting Zhu ◽  
Qingwen Jiang ◽  
Yiting Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lavage Fluid ◽  
False Negatives ◽  
Predictive Values ◽  
Bronchial Brushing ◽  
Diagnostic Role ◽  
Thin Layer Method ◽  
Liquid Based Cytology ◽  
Diagnosis Of Lung Cancer

Background: Liquid-based cytology (LBC) tests, including the liquid-based thin layer method, have demonstrated the highest potential for reducing false-negatives and improving sample quality. Method: This study aimed to evaluate the diagnostic role of LBC of bronchial brushing specimens in lung cancer. A total of 249 patients were analyzed in our study, involving 155 patients with combined bronchial brushing and bronchoalveolar lavage (BAL) and 94 patients with BAL alone. Results: The sensitivity in the combined bronchial brushing and BAL group was 61.4% in the diagnosis of lung cancer, which is much higher than with BAL alone. Rates of positive predictive values and negative predictive values in the combined group compared with the BALF alone group were 98.6% vs 100% and 47.6% vs 37.4%, respectively. Sensitivity in the BALF alone group was 12.5% in bronchoscopically invisible pulmonary lesions and as high as 52.1% in the combined group. Conclusion: The results from our study demonstrated that LBC of brushing samples could be used as an important complement of bronchoscopy and could have the potential to be widely applied.

Clinical application of the liquid-based cytological test in cytological screening of sputum for the diagnosis of lung cancer

Respirology ◽  
2009 ◽  
Vol 14 (1) ◽  
pp. 124-128 ◽  
Author(s):  
Guang-Ping WU ◽  
En-Hua WANG ◽  
Jian-Hua LI ◽  
Zhi-Min FU ◽  
Shuo HAN
Keyword(s):  
Lung Cancer ◽  
Clinical Application ◽  
Diagnosis Of Lung Cancer

COMPARISON OF CYTOLOGIC EXAMINATION OF BRONCHIAL WASHING SAMPLES VS BRONCHIAL BRUSHING IN THE DIAGNOSIS OF LUNG CANCER

CHEST Journal ◽  
2018 ◽  
Vol 154 (4) ◽  
pp. 891A
Author(s):  
ISAAC BINEY ◽  
PAUL BRANCA ◽  
J. TURNER ◽  
JOHN CALLISON ◽  
MICHAEL MCCORMACK ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cytologic Examination ◽  
Bronchial Brushing ◽  
Bronchial Washing ◽  
Diagnosis Of Lung Cancer

scholarly journals Correlation of bronchial brushing cytology with bronchial biopsy in diagnosis of lung cancer

2012 ◽  
Vol 10 (2) ◽  
pp. 4-7
Author(s):  
Eva Piya ◽  
Geeta Sayami ◽  
Brajendra Srivastava
Keyword(s):  
Lung Cancer ◽  
Cell Carcinoma ◽  
Excellent Result ◽  
Fiberoptic Bronchoscopy ◽  
Large Cell Carcinoma ◽  
University Teaching ◽  
Bronchial Biopsy ◽  
Bronchial Brushing ◽  
Brushing Cytology ◽  
Diagnosis Of Lung Cancer

Introduction: Lung cancer is one of the leading cause of death in western countries and is the second most common malignancy in Nepal. Fiberoptic bronchoscopy has an excellent result in diagnosis of lung cancer when combined with brushing cytology & biopsy. This prospective study was conducted at Tribhuvan University Teaching Hospital over the period of one year with the aim to correlate brushing cytology with biopsy in diagnosis of bronchoscopically visible lung cancer. Method: A total of 62 cases were included in this study on whom bronchoscopy was performed in endoscopy unit. Bronchial brushing, biopsy specimens were collected & processed accordingly. Results: Out of 62 cases, 53 were found to be malignant and 9 were inflammatory lesions. Thus, cytohistological correlation was done in 53 malignant cases. There were 38 male and 15 were female with a mean age of 54 years. The male:female ratio was 2.5:1. The most common type of carcinoma was squamous cell carcinoma (64.2%), followed by adenocarcinoma (18.8%), small cell carcinoma(13.2%), large cell carcinoma (1.9%), carcinoid tumor (1.9%). Sensitivity of the bronchial brushing was 94.6% while that of biopsy was 91.3%. Conclusion: Bronchial brushing cytology has better detection rate than biopsy in this study. However combination of these modaliti es gives higher detecti on rate for bronchoscopically visible tumor. Therefore, bronchial brush cytology should be performed whenever possible in all suspected cases of lung cancer. DOI: http://dx.doi.org/10.3126/mjsbh.v10i2.6454 Medical Journal of Shree Birendra Hospital July-Dec 2011 10(2) 4-7

Three-channel intelligent neoplasm classification system for the diagnosis of lung cancer

2019 ◽  
Vol 7 (3) ◽  
pp. 196-207
Author(s):  
Lev Utkin ◽  
Anna Meldo ◽  
Viktor Kryshtapovich ◽  
Viktor Tiulpin ◽  
Ernest Kasimov ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Classification System ◽  
Diagnosis Of Lung Cancer

SIALIC ACID IN THE PRIMARY AND DIFFERENTIAL DIAGNOSIS OF LUNG CANCER

2017 ◽  
Vol 63 (6) ◽  
pp. 926-932
Author(s):  
Lyudmila Belskaya ◽  
Viktor Kosenok ◽  
Ж. Массард
Keyword(s):  
Lung Cancer ◽  
Enzyme Activity ◽  
Optimization Problems ◽  
Primary Lung Cancer ◽  
Nonparametric Test ◽  
Nonsmall Cell Lung Cancer ◽  
Group Differences ◽  
Diagnosis Of Lung Cancer ◽  
And Control ◽  
Control Study

So far optimization problems for diagnostics and prognostication aids remained relevant for lung cancer as a leader in the structure of cancers. Objective: a search for regularities of changes in the saliva enzyme activity in patients with nonsmall cell lung cancer. In the case-control study, 505 people took part, divided into 2 groups: primary (lung cancer, n=290) and control (conventionally healthy, n=215). All the participants went through a questionnaire survey, saliva biochemical counts, and a histological verification of their diagnosis. The enzyme activity was measured with spectrophotometry. Between-group differences were measured with the nonparametric test. It was shown that in terms of lung cancer, we observe metabolic changes, described with the decreased de Ritis coefficient (p

Tumor Markers and Lung Cancer: Correlation between Serum and Bronchial Secretion Levels of Cea, Tpa, Canag Ca-50, Nse and Ferritin

1987 ◽  
Vol 2 (3) ◽  
pp. 151-156 ◽  
Author(s):  
Vincenzo Macchia ◽  
Angela Mariano ◽  
Mariarita Cavalcanti ◽  
Anna Coppa ◽  
Ciriaco Cecere ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Carcinoma ◽  
Simultaneous Determination ◽  
Neuron Specific Enolase ◽  
Bronchial Secretion ◽  
Lung Malignancy ◽  
Ca 50 ◽  
Oat Cell Carcinoma ◽  
Diagnosis Of Lung Cancer

The levels of carcinoembryonic antigeny (CEA), tissue polypeptide antigeny (TPA), CanAg 50, neuron specific enolase (NSE) and ferritin were determined in bronchial secretion and serum of patients with neoplastic and non-neoplastic lung diseases. Simultaneous determination of two or three markers in the serum and in bronchoalveolar lavage (BAL) may be clinically useful for the diagnosis of lung cancer and even for the type of tumor. The positivity of CEA determined simultaneously in serum and in BAL of patients with lung cancer is higher than 80% whereas in patients with benign lung disease it is lower than 40%. The simultaneous assay of TP A in serum and in BAL showed 100% positivity in patients with oat-cell carcinoma, the frequencies of positivity were similar in patients with non-oat-cell carcinoma. For NSE and CanAg CA-50 patients with oat-cell carinoma showed 100% positivity. Simultaneous assay of ferritin in serum and in BAL gave 85% positivity in patients with oat-cell carcinoma and only 23% in patients with non-oat-cell carcinoma. We conclude that the simultaneous determination of CEA and CanAg CA-50 or NSE in serum and in BAL is a useful aid in the diagnosis of lung malignancy.

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