Cyane-carvone, a Synthetic Derivative of Carvone, Inhibits Inflammatory Response by Reducing Cytokine Production and Oxidative Stress and Shows Antinociceptive Effect in Mice

Inflammation ◽  
2014 ◽  
Author(s):  
Thiago Henrique Costa Marques ◽  
Maria Leonildes Boavista Gomes Cast Marques ◽  
Jand-Venes R. Medeiros ◽  
Renan Oliveira Silva ◽  
André Luiz dos Reis Barbosa ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Inflammatory Response ◽  
Cytokine Production ◽  
Antinociceptive Effect ◽  
Synthetic Derivative ◽  
And Oxidative Stress

scholarly journals Phytol, a diterpene alcohol, inhibits the inflammatory response by reducing cytokine production and oxidative stress

2013 ◽  
Vol 28 (4) ◽  
pp. 455-464 ◽  
Author(s):  
Renan O. Silva ◽  
Francisca Beatriz M. Sousa ◽  
Samara R.B. Damasceno ◽  
Nathalia S. Carvalho ◽  
Valdelânia G. Silva ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Inflammatory Response ◽  
Cytokine Production ◽  
Diterpene Alcohol ◽  
And Oxidative Stress

scholarly journals Lysophosphatidylcholine Offsets the Protective Effects of Bone Marrow Mesenchymal Stem Cells on Inflammatory Response and Oxidative Stress Injury of Retinal Endothelial Cells via TLR4/NF-κB Signaling

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Haijun Zhao ◽  
Yanhui He
Keyword(s):  
Oxidative Stress ◽  
Stem Cells ◽  
Bone Marrow ◽  
Endothelial Cells ◽  
Inflammatory Response ◽  
Protective Effects ◽  
Stress Injury ◽  
Oxidative Stress Injury ◽  
Marrow Mesenchymal Stem Cells ◽  
And Oxidative Stress

Diabetic retinopathy (DR), as a major cause of blindness worldwide, is one common complication of diabetes mellitus. Inflammatory response and oxidative stress injury of endothelial cells play significant roles in the pathogenesis of DR. The study is aimed at investigating the effects of lysophosphatidylcholine (LPC) on the dysfunction of high glucose- (HG-) treated human retinal microvascular endothelial cells (HRMECs) after being cocultured with bone marrow mesenchymal stem cells (BMSCs) and the underlying regulatory mechanism. Coculture of BMSCs and HRMECs was performed in transwell chambers. The activities of antioxidant-related enzymes and molecules of oxidative stress injury and the contents of inflammatory cytokines were measured by ELISA. Flow cytometry analyzed the apoptosis of treated HRMECs. HRMECs were further treated with 10-50 μg/ml LPC to investigate the effect of LPC on the dysfunction of HRMECs. Western blotting was conducted to evaluate levels of TLR4 and p-NF-κB proteins. We found that BMSCs alleviated HG-induced inflammatory response and oxidative stress injury of HRMECs. Importantly, LPC offsets the protective effects of BMSCs on inflammatory response and oxidative stress injury of HRMECs. Furthermore, LPC upregulated the protein levels of TLR4 and p-NF-κB, activating the TLR4/NF-κB signaling pathway. Overall, our study demonstrated that LPC offsets the protective effects of BMSCs on inflammatory response and oxidative stress injury of HRMECs via TLR4/NF-κB signaling.

The investigation of the relationships of demodex density with inflammatory response and oxidative stress in rosacea

2018 ◽  
Vol 310 (9) ◽  
pp. 759-767 ◽  
Author(s):  
Tuğba Falay Gur ◽  
Aslı Vefa Erdemir ◽  
Mehmet Salih Gurel ◽  
Abdurrahim Kocyigit ◽  
Eray Metin Guler ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Inflammatory Response ◽  
And Oxidative Stress

scholarly journals Dandelion prevents liver fibrosis, inflammatory response, and oxidative stress in rats

2020 ◽  
Vol 81 (1) ◽  
Author(s):  
Alaaeldin Ahmed Hamza ◽  
Mona Gamel Mohamed ◽  
Fawzy Mohamed Lashin ◽  
Amr Amin
Keyword(s):  
Oxidative Stress ◽  
Liver Fibrosis ◽  
Inflammatory Response ◽  
And Oxidative Stress

Riparin B, a Synthetic Compound Analogue of Riparin, Inhibits the Systemic Inflammatory Response and Oxidative Stress in Mice

Inflammation ◽  
2015 ◽  
Vol 38 (6) ◽  
pp. 2203-2215 ◽  
Author(s):  
Renata Fortes Santiago ◽  
Tarcisio Vieira de Brito ◽  
Jordana Maia Dias ◽  
Genilson José Dias ◽  
José Simião da Cruz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Inflammatory Response ◽  
Systemic Inflammatory Response ◽  
Synthetic Compound ◽  
And Oxidative Stress
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