scholarly journals Using the Childhood Autism Rating Scale to Diagnose Autism Spectrum Disorders

2010 ◽  
Vol 40 (7) ◽  
pp. 787-799 ◽  
Author(s):  
Colby Chlebowski ◽  
James A. Green ◽  
Marianne L. Barton ◽  
Deborah Fein
Keyword(s):  
Autism Spectrum Disorders ◽  
Rating Scale ◽  
Autism Spectrum ◽  
Childhood Autism ◽  
Childhood Autism Rating Scale ◽  
Spectrum Disorders

scholarly journals Parent-reported feeding characteristics in children with ASD vs. children who are typically developing

2021 ◽  
Vol 37 (1) ◽  
Author(s):  
Nesreen Fathi Mahmoud ◽  
Rehab Safwat Abdelhameed ◽  
Sherif A. Abdelmonam ◽  
Ahmed Ali Abdelmonem ◽  
Doaa Mahmoud Khalil ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Rating Scale ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Childhood Autism Rating Scale ◽  
Typically Developing ◽  
Feeding Behaviors ◽  
Children With Asd ◽  
The Mean ◽  
Spectrum Disorders

Abstract Background Parents of children with autism spectrum disorders (ASDs) often report that their children have multiple dietary behavior problems than parents of typically developing (TD) children do. This may affect proper nutrition and subsequently adequate growth and development in children with ASD. The current study aimed to assess the feeding behavior in recently diagnosed children with autism spectrum disorders (ASD) ranged in age from 2 to 4 years and compare it with typically developing (TD) children and to explore the relationship between feeding behaviors and autism severity using the Montreal Children’s Hospital Feeding Scale (MCH) and Childhood Autism Rating Scale (CARS), respectively. Parents of 35 preschool children (2–4 years) with ASD completed reports of physical measurements, feeding interview, Childhood Autism Rating Scale (CARS), and Montreal Children’s Hospital Feeding Scale (MCH Feeding-Scale). The collected data from parents of children with ASD were analyzed and compared with 70 typically developed children matched with age and sex. Results ASD children showed statistically significantly more problematic feeding behaviors in most of the assessed eating characters compared with TD children, e.g., food neophobia, eating non-food items instead of food, requiring assistance during eating, and feeding avoidance to particular textures and taste. The mean total score of the MCH feeding scale differed significantly between children with ASD and TD children. No correlation was found between the mean total score of the MCH feeding scale and CARS scores. Conclusion Our findings revealed a high rate of behavioral feeding problems in children with ASD. Future work will be needed to follow up the feeding behaviors and to develop practical feeding approaches for ASD children to maintain nutritional adequacy.

scholarly journals Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders

2018 ◽  
Vol 17 (8) ◽  
pp. 626-639 ◽  
Author(s):  
Heidi Ormstad ◽  
Vesna Bryn ◽  
Robert Verkerk ◽  
Ola H. Skjeldal ◽  
Bente Halvorsen ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Neurotrophic Factor ◽  
Serum Levels ◽  
Brain Derived Neurotrophic Factor ◽  
Autism Spectrum ◽  
Childhood Autism ◽  
Total Blood ◽  
Healthy Control ◽  
Tryptophan Catabolites ◽  
Spectrum Disorders

Background: There is evidence that changes in neuro-immune responses coupled with dysfunctions in serotonin metabolism underpin the pathophysiology of autism spectrum disorders (ASD). Objective: This study aimed to delineate whether ASD subgroups or characteristics show aberrations in tryptophan and brain-derived neurotrophic factor (BDNF) metabolism. Methods: 65 individuals with ASD (diagnosed according to ICD criteria) and 30 healthy control patients were included. Measured were serum levels of tryptophan, kynurenine (KYN), kynurenic acid (KA), quinolinic acid (QA), BDNF and PRO-BDNF and total blood 5-HT and 5-OH-tryptophan (5-HTP). Results: Elevated BDNF levels and lower tryptophan and KA levels were characteristics of both childhood autism and intellectual disability disorder, whilst elevated tryptophan and lower 5-HT synthesis were hallmarks of Asperger syndrome. A pathological MRI was associated with elevated tryptophan and lowered KA. Abnormal EEG results and dysmorphology were both associated with an elevated BDNF/ PRO-BDNF ratio. Any brain pathology and gastro-intestinal symptoms were accompanied by lowered KA. Conclusions: Increased BDNF production and changes in the metabolism of tryptophan are associated with many ASD characteristics, showing particularly strong associations with childhood autism and Intellectual and Developmental Disabilities. Peripheral BDNF and tryptophan metabolism appear to take part in the pathophysiology of autism spectrum disorders and their phenotypes.

scholarly journals Neural Basis of Visual Attentional Orienting in Childhood Autism Spectrum Disorders

2016 ◽  
Vol 47 (1) ◽  
pp. 58-67 ◽  
Author(s):  
Eric R. Murphy ◽  
Megan Norr ◽  
John F. Strang ◽  
Lauren Kenworthy ◽  
William D. Gaillard ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Autism Spectrum ◽  
Childhood Autism ◽  
Attentional Orienting ◽  
Neural Basis ◽  
Spectrum Disorders

Residential placement and quality of life for adults with severe autism spectrum disorders and severe-to-profound intellectual disabilities

2017 ◽  
Vol 3 (4) ◽  
pp. 187-205
Author(s):  
Giuliana Galli Carminati ◽  
Federico Carminati ◽  
Rachel Lehotkay ◽  
Erica Nora Lorincz ◽  
Viviane Subirade-Jacopit ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Autism Spectrum Disorders ◽  
Living Arrangements ◽  
Rating Scale ◽  
Autism Spectrum ◽  
Aberrant Behavior ◽  
Content Type ◽  
Severe Intellectual Disability ◽  
Spectrum Disorders

Purpose The purpose of this paper is to evaluate the relationship between some main characteristics of different living arrangements and the quality of life (QoL) of their users with severe intellectual disability and low-functioning autism spectrum disorders. Design/methodology/approach Study participants were assessed for ASD severity through the Childhood Autism Rating Scale or the Vineland Adaptive Behavior Scales (VABS): for behavioral problems with the aberrant behavior checklist (ABC); for perception of efficacy and satisfaction with care, through an adapted Visual Analogue Scale; and for QoL with the QoL inventory in residential environments (validated in French as Inventaire de la Qualité de Vie en Milieu Résidentiel). Because the goal was to define a “residential profile (RP),” the authors evaluated each participating residence with the Working Methods Scale and the questionnaire on residential parameters. Findings The RP allowed for the classification of the residences into three clusters. The authors found no clear relationship between QoL and the RP clusters, but the authors found the RP clusters to be significantly correlated with ABC factors F1 (irritability, agitation, crying) and F2 (lethargy, social withdrawal), and VABS scores for living, socialization, and motor skills. Originality/value RPs were more strongly correlated with ABC items and the ability to cope with everyday life than with QoL. The authors hypothesize that RP is correlated with both aberrant behavior and the autonomy of residents and that QoL remains relatively stable. Therefore, RP is correlated with the status of the residents; however, this appears not to be correlated with their QoL.

Correlations Between the Parents’ ADHD Score and the Child's ADOS Score in Parents of Children with Comorbid ADHD–Autism Spectrum Disorder

2017 ◽  
Vol 41 (S1) ◽  
pp. S221-S221
Author(s):  
F. Rad ◽  
L. Kobylinska ◽  
I. Mihailescu ◽  
A. Buica ◽  
I. Dobrescu
Keyword(s):  
Autism Spectrum Disorder ◽  
Autism Spectrum Disorders ◽  
Adult Adhd ◽  
Rating Scale ◽  
Clinical Symptoms ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Autism Spectrum Quotient ◽  
Spectrum Disorders

From assortative mating theory to genetic background, several ethipathogenic hypotheses in ASD deal with the traits of parents.Backgroundseveral ethipathogenic hypotheses in ASD deal with the traits of parents. The objectives of our study were to measure the ADHD and autism spectrum disorder quotients in parents of children diagnosed with ASD comorbid with ADHD and to correlate the measurements for the tests in parents with those in their children. The specific aim was to identify whether any significant correlations exist.MethodFifty-two pairs of parents of children with autism spectrum disorders and ADHD were included in this study, based on informed consent and the ethical committee's approval. The child's diagnosis was established by a specialist in child and adolescent psychiatry, based on the child's clinical symptoms and on specific diagnostic scales, such as the ADOS and ADHD-rating scale. The parents completed an Autism Spectrum Quotient Scale (ASQS) and an adult ADHD scale. The data were analyzed using SPSS 22.0 and Excel. The correlations were verified using Spearman's non-parametric correlation test.ResultsThere was a strong correlation between the parents’ ADHD scores (r = 0.5, P < 0.001), and a reverse medium correlation between the mother's ADHD score and the child's ADOS score (r = –0.32, P = 0.02). The father's ASQS and ADHD scores correlated between each other (r = 0.31, P = 0.02). There were no correlations between the parents’ and the child's ADHD score, nor between the child's ADOS score and the parents’ ASQS scores.ConclusionOur results suggest that ADHD symptoms in parents of children with autism spectrum disorders comorbid with ADHD might be predictors for the child's prognosis.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Controversial issues in comorbidity between epilepsy and autism: subclinical epileptiform activity and autistic epileptiform regression

2019 ◽  
Vol 14 (1) ◽  
pp. 40-48
Author(s):  
G. V. Kuzmich ◽  
A. N. Sinelnikova ◽  
K. Yu. Mukhin
Keyword(s):  
Early Childhood ◽  
Autism Spectrum Disorders ◽  
Present Article ◽  
Clinical Significance ◽  
Epileptiform Activity ◽  
Autism Spectrum ◽  
Childhood Autism ◽  
Controversial Issues ◽  
Spectrum Disorders ◽  
The Impact

Early childhood autism, or autism spectrum disorders, is an extremely heterogeneous group of conditions that share similar symptoms of dysontogenesis. The most significant comorbidity in patients with autism is epilepsy, which is still associated with a variety of controversies. The present article covers the most controversial aspects of comorbidity between autism and epilepsy, including the impact of psychopharmacotherapy on the risk of epilepsy, clinical significance of epileptiform activity on the electroencephalogram in patients without epilepsy, and criteria for and prevalence of autistic epileptiform regression syndrome. We found that there is still a lack of reliable evidence for the majority of issues related to the combination of autism and epilepsy. We emphasize the need for further studies. We also provide a detailed description of the history, criteria, prevalence, and clinical examples of autistic epileptiform regression syndrome.

Sign in / Sign up

Export Citation Format

Share Document