scholarly journals The Predictive Value of the AQ and the SRS-A in the Diagnosis of ASD in Adults in Clinical Practice

Author(s):  
M. L. Bezemer ◽  
E. M. A. Blijd-Hoogewys ◽  
M. Meek-Heekelaar

Abstract Questionnaires are widely used in autism assessment. However, their psychometric properties are generally not evaluated in clinical practice, and the comparability and applicability of such research is limited because questionnaires are often not simultaneously evaluated. This certainly pertains to predictive values which are highly population and setting specific. This study evaluated the power of AQ and SRS-A in predicting an ASD diagnosis within the same clinical population. The patient records of 92 adults, referred for autism assessment, were analyzed. The AQ proved somewhat better than the SRS-A at discriminating and predicting autism. The predictive values of both questionnaires were lower than reported in general population studies. Psychometric results in core publications appear less representative for clinical practice.

2002 ◽  
Vol 15 (3) ◽  
pp. 187-197 ◽  
Author(s):  
Jacqueline M. Golding ◽  
Sharon C. Wilsnack ◽  
M. Lynne Cooper

2015 ◽  
Vol 33 (6) ◽  
pp. 1144-1152 ◽  
Author(s):  
Dai-Hua Tsai ◽  
Idris Guessous ◽  
Michael Riediker ◽  
Fred Paccaud ◽  
Jean-Michel Gaspoz ◽  
...  

Science ◽  
2007 ◽  
Vol 315 (5809) ◽  
pp. 187.2-187 ◽  
Author(s):  
Christian Dina ◽  
David Meyre ◽  
Chantal Samson ◽  
Jean Tichet ◽  
Michel Marre ◽  
...  

Herbert et al. (Reports, 14 April 2006, p. 279) reported an association between the INSIG2 gene variant rs7566605 and obesity in four sample populations, under a recessive model. We attempted to replicate this result in 10,265 Caucasian individuals, combining family-based, case-control, and general population studies, but found no support for a major role of this variant in obesity.


2003 ◽  
Vol 14 (3) ◽  
pp. 148-161 ◽  
Author(s):  
David Gisselquist ◽  
John J Potterat ◽  
Stuart Brody ◽  
Francois Vachon

The consensus among influential AIDS experts that heterosexual transmission accounts for 90% of HIV infections in African adults emerged no later than 1988. We examine evidence available through 1988, including risk measures associating HIV with sexual behaviour, health care, and socioeconomic variables, HIV in children, and risks for HIV in prostitutes and STD patients. Evidence permits the interpretation that health care exposures caused more HIV than sexual transmission. In general population studies, crude risk measures associate more than half of HIV infections in adults with health care exposures. Early studies did not resolve questions about direction of causation (between injections and HIV) and confound (between injections and STD). Preconceptions about African sexuality and a desire to maintain public trust in health care may have encouraged discounting of evidence. We urge renewed, evidence-based, investigations into the proportion of African HIV from non-sexual exposures.


1997 ◽  
Vol 16 (5) ◽  
pp. 417-425 ◽  
Author(s):  
Jacqueline M. Golding ◽  
M. Lynne Cooper ◽  
Linda K. George

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