scholarly journals Proof-of-Concept Study: a Mobile Application to Derive Clinical Outcome Measures from Expression and Speech for Mental Health Status Evaluation

2020 ◽  
Vol 44 (12) ◽  
Author(s):  
Francesco Luke Siena ◽  
Michael Vernon ◽  
Paul Watts ◽  
Bill Byrom ◽  
David Crundall ◽  
...  
Keyword(s):  
Health Status ◽  
Facial Expression ◽  
Outcome Measures ◽  
Mobile Application ◽  
Autism Spectrum ◽  
Mobile App ◽  
Proof Of Concept ◽  
Concept Study ◽  
Video Footage ◽  
Video Diary

AbstractThis proof-of-concept study aimed to assess the ability of a mobile application and cloud analytics software solution to extract facial expression information from participant selfie videos. This is one component of a solution aimed at extracting possible health outcome measures based on expression, voice acoustics and speech sentiment from video diary data provided by patients. Forty healthy volunteers viewed 21 validated images from the International Affective Picture System database through a mobile app which simultaneously captured video footage of their face using the selfie camera. Images were intended to be associated with the following emotional responses: anger, disgust, sadness, contempt, fear, surprise and happiness. Both valence and arousal scores estimated from the video footage associated with each image were adequate predictors of the IAPS image scores (p < 0.001 and p = 0.04 respectively). 12.2% of images were categorised as containing a positive expression response in line with the target expression; with happiness and sadness responses providing the greatest frequency of responders: 41.0% and 21.4% respectively. 71.2% of images were associated with no change in expression. This proof-of-concept study provides early encouraging findings that changes in facial expression can be detected when they exist. Combined with voice acoustical measures and speech sentiment analysis, this may lead to novel measures of health status in patients using a video diary in indications including depression, schizophrenia, autism spectrum disorder and PTSD amongst other conditions.

scholarly journals Mobile App-based documentation of patient-reported outcomes — 3-months results from a proof-of-concept study on modern rheumatology patient management

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Jutta G. Richter ◽  
Christina Nannen ◽  
Gamal Chehab ◽  
Hasan Acar ◽  
Arnd Becker ◽  
...  
Keyword(s):  
Disease Activity ◽  
Disease Surveillance ◽  
Patient Management ◽  
Activity Index ◽  
Retention Rate ◽  
Likert Scale ◽  
Mobile App ◽  
Proof Of Concept ◽  
Concept Study ◽  
Patient Reported

Abstract Background Mobile medical applications (Apps) offer innovative solutions for patients’ self-monitoring and new patient management opportunities. Prior to routine clinical application feasibility and acceptance of disease surveillance using an App that includes electronic (e) patient-reported outcome measures (PROMs) warrant evaluation. Therefore, we performed a proof-of-concept study in which rheumatoid arthritis (RA) patients used an App (RheumaLive) to document their disease. Methods Accurate PROM reporting via an App in comparison to paper-based versions was investigated to exclude media bias. Sixty participants recruited from 268 consecutive RA outpatients completed paper-based and electronic PROMs (Hannover Functional Questionnaire/derived HAQ; modified RA disease activity index) using the App at baseline and follow-up visits. Between visits, patients used their App on their own smartphone according to their preferences. The equivalence of PROM data and user experiences from patients and physicians were evaluated. Results Patients’ (78.3% female) mean (SD) age was 50.1 (13.1) years, disease duration 10.5 (9.1) years, and paper-based HAQ 0.78 (0.59). Mean confidence in Apps scored 3.5 (1.1, Likert scale 1 to 6). ePROMs’ scores obtained by patients’ data entry in the App were equivalent to paper-based ones and preferred by the patients. After 3 months, the App retention rate was 71.7%. Patients' overall satisfaction with the App was 2.2 (0.9, Likert scale 1 to 6). Patients and physicians valued the App, i.e., for patient-physician interaction: 87% reported that it was easier for them to document the course of the disease using the App than “only” answering questions about their current health during routine outpatient visits. Further App use was recommended in 77.3% of the patients, and according to physicians, in seven patients, the App use contributed to an increased adherence to therapy. Conclusion Our study provides an essential basis for the broader implementation of medical Apps in routine care. We demonstrated the feasibility and acceptance of disease surveillance using a smartphone App in RA. App use was convincing as a reliable option to perform continuous, remote monitoring of disease activity and treatment efficacy. Trial registration ClinicalTrials.gov, NCT02565225. Registered on September 16, 2015 (retrospectively registered).

scholarly journals Collecting standardised oral health data via mobile application: A proof of concept study in the Netherlands

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0191385 ◽  
Author(s):  
Joost C. L. den Boer ◽  
Ward van Dijk ◽  
Virginie Horn ◽  
Patrick Hescot ◽  
Josef J. M. Bruers
Keyword(s):  
Oral Health ◽  
The Netherlands ◽  
Mobile Application ◽  
Health Data ◽  
Proof Of Concept ◽  
Concept Study

scholarly journals Prebiotic supplementation does not affect reading and cognitive performance in children: A randomised placebo-controlled study

2019 ◽  
Vol 34 (1) ◽  
pp. 148-152
Author(s):  
Liliana P Capitão ◽  
Rita Baião ◽  
Hee K Baek ◽  
Nils Kappelmann ◽  
Rachel Sharman ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Cognitive Performance ◽  
Outcome Measures ◽  
Reading Scores ◽  
Controlled Study ◽  
Proof Of Concept ◽  
Concept Study ◽  
Sleep Behaviour

Based on the emerging interest in the effects of gut microbiota on cognition, this proof-of-concept study assessed how children aged 7 to 9 with low reading scores responded to the ingestion of a 3-month prebiotic supplement versus a placebo. As a secondary aim, the effects of the prebiotic on cognition, sleep, behaviour, mood, anxiety, and cortisol were assessed. In this sample, the prebiotic did not affect any of the outcome measures.

scholarly journals Can biological components predict short-term evolution in Autism Spectrum Disorders? A proof-of-concept study

2016 ◽  
Vol 42 (1) ◽  
Author(s):  
Leonardo Emberti Gialloreti ◽  
Arianna Benvenuto ◽  
Barbara Battan ◽  
Francesca Benassi ◽  
Paolo Curatolo
Keyword(s):  
Autism Spectrum Disorders ◽  
Autism Spectrum ◽  
Proof Of Concept ◽  
Short Term ◽  
Concept Study ◽  
Term Evolution ◽  
Spectrum Disorders

scholarly journals An App to encourage social interaction by children with Autism Spectrum Disorder: A proof of concept study

2018 ◽  
Vol 46 (1) ◽  
pp. 12-18
Author(s):  
Amanda Wilkinson ◽  
Ashton Edwards ◽  
Mary Gray ◽  
Tharindu Ranabahu ◽  
Megan Steenkamp ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Social Interaction ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Proof Of Concept ◽  
Concept Study

scholarly journals PMH6 DERIVING CLINICAL OUTCOME MEASURES FROM EXPRESSION AND SPEECH: RESULTS OF A PROOF OF CONCEPT STUDY

2020 ◽  
Vol 23 ◽  
pp. S200-S201
Author(s):  
F. Siena ◽  
M. Vernon ◽  
P. Watts ◽  
D. Crundall ◽  
B. Byrom ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Outcome Measures ◽  
Proof Of Concept ◽  
Concept Study

scholarly journals Mapping drinking water and quality of life aspects in urban settings: an application of the urban exposome

2018 ◽  
Author(s):  
Xanthi D. Andrianou ◽  
Chava van der Lek ◽  
Pantelis Charisiadis ◽  
Solomon Ioannou ◽  
Kalliopi N. Fotopoulou ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Water Quality ◽  
Drinking Water ◽  
Health Status ◽  
Quality Parameters ◽  
Drinking Water Quality ◽  
Water Quality Parameters ◽  
Proof Of Concept ◽  
Concept Study

AbstractCities face rapid changes leading to increasing inequalities and emerging public health issues that require cost-effective interventions. The urban exposome framework constitutes a novel approach in tackling city-wide challenges, such as those of drinking water quality and quality of life. In this proof-of-concept study, we presented part of the urban exposome of Limassol (Cyprus) focusing on chemical and microbial drinking water quality parameters and their association with urban neighborhood indicators. A perceptions study and an urban population study was conducted. We mapped the water quality parameters and participants’ opinions on city life (i.e. neighborhood life, health care and green space access) using quarters (small administrative areas) as the reference unit of the city. In an exploratory environment-wide association study analysis, we used all variables (questionnaire responses and water quality metrics) to describe correlations between them accounting, also, for self-reported health status. Overall, urban drinking-water quality using conventional indicators of chemical (disinfection byproducts-trihalomethanes) and microbial (coliforms, E. coli, and Enterococci) quality did not raise particular concerns. The general health and chronic health status of the urban participants were significantly (all >FDR corrected p value of 0.1) associated with different health conditions such as hypertension and asthma, or having financial issues in access to dental care. Additionally, correlations between trihalomethanes and participant characteristics (e.g. household cleaning, drinking water habits) were documented. This proof-of-concept study showed the potential of using integrative approaches to develop urban exposomic profiles and identifying within-city differentiated environmental and health indicators. The characterization of the urban exposome of Limassol will be expanded via the inclusion of biomonitoring tools and untargeted metabolomics platforms.

Sign in / Sign up

Export Citation Format

Share Document