scholarly journals A Systematic Review of Workplace Interventions to Rehabilitate Musculoskeletal Disorders Among Employees with Physical Demanding Work

2020 ◽  
Vol 30 (4) ◽  
pp. 588-612 ◽  
Author(s):  
Emil Sundstrup ◽  
Karina Glies Vincents Seeberg ◽  
Elizabeth Bengtsen ◽  
Lars Louis Andersen
Keyword(s):  
Systematic Review ◽  
Musculoskeletal Disorders ◽  
Strong Evidence ◽  
Scientific Literature ◽  
Evidence Synthesis ◽  
Participatory Ergonomics ◽  
Workplace Interventions ◽  
Pain Symptoms ◽  
Positive Effect ◽  
Physically Demanding Work

AbstractPurpose This systematic review investigates the effectiveness of workplace interventions to rehabilitate musculoskeletal disorders (MSDs) among employees with physically demanding work. Methods A systematic search was conducted in bibliographic databases including PubMed and Web of Science Core Collection for English articles published from 1998 to 2018. The PICO strategy guided the assessment of study relevance and the bibliographical search for randomized controlled trials (RCTs) and non-RCTs in which (1) participants were adult workers with physically demanding work and MSD (including specific and non-specific MSD and musculoskeletal pain, symptoms, and discomfort), (2) interventions were initiated and/or carried out at the workplace, (3) a comparison group was included, and (4) a measure of MSD was reported (including musculoskeletal pain, symptoms, prevalence or discomfort). The quality assessment and evidence synthesis adhered to the guidelines developed by the Institute for Work & Health (Toronto, Canada) focusing on developing practical recommendations for stakeholders. Relevant stakeholders were engaged in the review process. Results Level of evidence from 54 high and medium quality studies showed moderate evidence of a positive effect of physical exercise. Within this domain, there was strong evidence of a positive effect of workplace strength training. There was limited evidence for ergonomics and strong evidence for no benefit of participatory ergonomics, multifaceted interventions, and stress management. No intervention domains were associated with “negative effects”. Conclusions The evidence synthesis recommends that implementing strength training at the workplace can reduce MSD among workers with physically demanding work. In regard to workplace ergonomics, there was not enough evidence from the scientific literature to guide current practices. Based on the scientific literature, participatory ergonomics and multifaceted workplace interventions seem to have no beneficial effect on reducing MSD among this group of workers. As these interventional domains were very heterogeneous, it should also be recognized that general conclusions about their effectiveness should be done with care.Systematic review registration PROSPERO CRD42018116752 (https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=116752).

scholarly journals Topical glyceryl trinitrate for the treatment of tendinopathies: a systematic review

2018 ◽  
Vol 53 (4) ◽  
pp. 251-262 ◽  
Author(s):  
Dimitris Challoumas ◽  
Paul D Kirwan ◽  
Dmytro Borysov ◽  
Christopher Clifford ◽  
Michael McLean ◽  
...  
Keyword(s):  
Systematic Review ◽  
Glyceryl Trinitrate ◽  
Strong Evidence ◽  
Evidence Synthesis ◽  
Clinical Effects ◽  
Range Of Movement ◽  
Level Of Evidence ◽  
Moderate Evidence ◽  
Best Evidence Synthesis ◽  
Topical Glyceryl Trinitrate

ObjectiveTo produce a best evidence synthesis of the clinical effects of topical glyceryl trinitrate (GTN) in the treatment of tendinopathies.DesignA systematic review of published randomised controlled trials (RCTs) of the use of GTN in patients with tendinopathy.Data sourcesMEDLINE, Embase, Scopus and CINAHL from database inception to January 2018.MethodsWe examined RCTs comparing the effects of topical GTN with either placebo or other treatments on tendinopathy. Overall quality of each eligible study was determined based on a combined assessment of internal validity, external validity and precision. The level of evidence for each assessed parameter was rated based on the system by van Tulderet al.ResultsA total of 10 eligible RCTs were identified including patients with tendinopathy of the rotator cuff (n=4), wrist extensors (n=3), Achilles (n=2) and patellar (n=1) tendons. For all tendinopathies, improvements in pain were significant when comparing GTN versus placebo in the short term (<8 weeks; poor evidence). Significant improvements in midterm outcomes for treatment with GTN versus placebo included the following: patient satisfaction (strong evidence); chances of being asymptomatic with activities of daily living (strong evidence); range of movement (moderate evidence); strength (moderate evidence); pain (at night and with activity; poor evidence) and local tenderness (poor evidence). Patients treated with topical GTN reported a higher incidence of headaches than those who received placebo (moderate evidence).Conclusions and relevanceTreatment of tendinopathies with topical GTN for up to 6 months appears to be superior to placebo and may therefore be a useful adjunct to the treating healthcare professions.

scholarly journals Is lower hip range of motion a risk factor for groin pain in athletes? A systematic review with clinical applications

2017 ◽  
Vol 51 (22) ◽  
pp. 1611-1621 ◽  
Author(s):  
Igor Tak ◽  
Leonie Engelaar ◽  
Vincent Gouttebarge ◽  
Maarten Barendrecht ◽  
Sylvia Van den Heuvel ◽  
...  
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Range Of Motion ◽  
Strong Evidence ◽  
Groin Pain ◽  
Evidence Synthesis ◽  
Case Control ◽  
Measurement Properties ◽  
Total Quality ◽  
Hip Range Of Motion

BackgroundWhether hip range of motion (ROM) is a risk factor for groin pain in athletes is not known.ObjectivesTo systematically review the relationship between hip ROM and groin pain in athletes in cross-sectional/case–control and prospective studies.Study designSystematic review, prospectively registered (PROSPERO) according to PRISMA guidelines.MethodsPubmed, Embase, CINAHL and SPORTDiscus were systematically searched up to December 2015. Two authors performed study selection, data extraction/analysis, quality assessment (Critical Appraisal Skills Programme) and strength of evidence synthesis.ResultsWe identified seven prospective and four case–control studies. The total quality score ranged from 29% to 92%. Heterogeneity in groin pain classification, injury definitions and physical assessment precluded data pooling. There was strong evidence that total rotation of both hips below 85° measured at the pre-season screening was a risk factor for groin pain development. Strong evidence suggested that internal rotation, abduction and extension were not associated with the risk or presence of groin pain.ConclusionTotal hip ROM is the factor most consistently related to groin pain in athletes. Screening for hip ROM is unlikely to correctly identify an athlete at risk of developing groin pain because of the small ROM differences found and poor ROM measurement properties.

scholarly journals Prognostic Factors to Determine Survivorship of Meniscal Allograft Transplant: A Systematic Review

2021 ◽  
Vol 9 (6) ◽  
pp. 232596712110072
Author(s):  
Ding-yu Wang ◽  
Cassandra A. Lee ◽  
Yan-zhang Li ◽  
Bo Zhang ◽  
Nan Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Factors ◽  
Acl Reconstruction ◽  
Strong Evidence ◽  
Evidence Synthesis ◽  
Cartilage Damage ◽  
Older Age ◽  
Cochrane Central Register ◽  
Meniscal Allograft ◽  
Best Evidence Synthesis

Background: There is much room for improvement and optimization of meniscal allograft survivorship. Purpose: To understand prognostic factors for survivorship using evidence-based selection criteria in order to identify patients who would best benefit from meniscal allograft transplant (MAT). Study Design: Systematic review; Level of evidence, 4. Methods: We conducted this systematic review to analyze prognostic factors for survivorship of MAT. The Cochrane Central Register, PubMed publisher, Embase.com , and Web of Science databases were searched through August 8, 2019. Included studies entailed patients of any age who received MAT with a reported association between prognostic factors and survivorship of the allograft. Two reviewers independently screened all titles and abstracts for eligibility, extracted the data, assessed the risk of bias using the Newcastle-Ottawa Scale, and performed a best-evidence synthesis. Results: The review included 18 studies with a total of 1920 patients. The mean follow-up time was 6.0 years (range, 2.1-11.2 years). A total of 20 prognostic factors were identified and shown to be associated with survivorship of MAT. Strong evidence was found that severe cartilage damage was associated with poor survivorship. Strong evidence was also found showing that sex, knee compartment, surgical side, concomitant anterior cruciate ligament (ACL) reconstruction, and concomitant osteotomy for malalignment had no effect on survivorship. Moderate evidence was found that body mass index (<36), tobacco use, and arthroscopic versus open procedure had no influence on survivorship. Conflicting evidence was found that older age and kissing cartilage lesions (lesions on both the femur and tibia vs on a single side) decreased survivorship. Conclusion: Severe cartilage damage decreases the survivorship of MAT. Concomitant ACL reconstruction and osteotomy showed no relationship to survivorship. Many determinants showed conflicting and limited evidence. Older age may be of interest and should be further studied.

scholarly journals AB0877 CLINICAL EFFICACY AND SAFETY PROFILE OF TOPICAL ETOFENAMATE IN THE TREATMENT OF PATIENTS WITH MUSCULOSKELETAL DISORDERS: RESULTS OF A SYSTEMATIC REVIEW

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1744.2-1744
Author(s):  
A. Pereira ◽  
D. Marinho
Keyword(s):  
Systematic Review ◽  
Musculoskeletal Disorders ◽  
Clinical Evidence ◽  
Therapeutic Option ◽  
Efficacy And Safety ◽  
Topical Formulations ◽  
Reduction Of Pain ◽  
Pubmed Search ◽  
Pain Symptoms ◽  
Topical Nsaids

Background:Musculoskeletal disorders affect millions of people of all ages around the world [1]. Nonsteroidal anti-inflammatory drugs (NSAIDs) are, in general, the cornerstone of musculoskeletal pain management; however, systemic adverse events with oral formulations of NSAIDs are common. To address this, topical formulations of some NSAIDs have been developed. [2] Although there are many nonsteroidal anti-inflammatories, only a few are used as local therapeutics. This is because the physicochemical properties of these substances, which were originally developed for oral administration, frequently do not guarantee a satisfactory pharmaceutical formulation with satisfactory topical absorption. [3]Objectives:The aim of this systematic review was to assess the available evidence on the efficacy and safety of the topical formulations of the NSAID etofenamate in patients with musculoskeletal disorders.Methods:A systematic search of PubMed and Web of Science was conducted, using the key words (topical etofenamate efficacy) OR (topical etofenamate safety) OR (topical etofenamate effectiveness) to identify studies of etofenamate published from inception to November 2018. Some published manuscripts of interest known by the authors but not identified in the PubMed search were also added to ensure the review article was as comprehensive as possible.Results:Overall, 12 studies were identified. [3-14] These studies demonstrated the ability of topical etofenamate (administered either in gel [5% or 10%], cream [10%] or lotion [10%] formulations]) to improve pain and reduce inflammation in patients with musculoskeletal disorders, including blunt injuries and rheumatic diseases. Etofenamate was shown to have an overall efficacy that was superior to other topical NSAIDs, such as 1% indomethacin and 1% diclofenac, and to be as effective as topical formulations of 2.5% ketoprofen gel and 2% ketorolac gel (although ketorolac suggested a better elimination of pain at some time points). Overall, when compared to placebo, etofenamate gel 5% demonstrated significant better results in the reduction of pain symptoms (with or without combination with ultraphonophoresis). Furthermore, clinical evidence indicates that etofenamate is generally well tolerated in these indications.Conclusion:The available clinical evidence suggests that etofenamate could be an effective therapeutic option for the management of musculoskeletal disorders, such as blunt traumas, lumbago or osteoarthritis. However, larger and well-controlled clinical trials comparing the efficacy and safety of etofenamate with other newer topical NSAIDs are warranted.References:[1]Atchison JW, et al. J Manag Care Pharm. 2013; 19: S3-19.[2]Haroutiunian S, et al. Pain Med. 2010; 11: 535-49.[3]Pelster B, et al. ZFA. 1992; 68: 364-7.[4]Schneider H. Therapiewoche. 1983;33:5809-18.[5]Miehlke RK, et al. Med Welt. 1985;36:103-6.[6]Rechziegler H, et al. Therapiewoche. 1986;36:5347-51.[7]Hallmeier B. Rheuma. 1988;8:183-6.[8]Rechziegler H. Therapiewoche. 1983;33:703-7.[9]Matsuno S, et al. J Med Pharm Sci. 1983;9:349-67.[10]Nagaya I, et al. Med Pharmacy. 1982;8:1549-82.[11]Ascher R, et al. Fortschr Med. 1982;37:1729-34.[12]Billigmann P, et al. Praktische Traumatologie Sportmedizin. 1992;2:72-7.[13]Diebschlag W, et al. J Clin Pharmacol. 1990;30:82-9.[14]Matucci-Cerinic M, et al. Int J Clin Pharmacol Res. 1988;8:157-60Disclosure of Interests:Anabela Pereira Consultant of: Recently, I was a paid consultant of Bial., Speakers bureau: I have been a paid speaker for Bial., Daniela Marinho Employee of: I’m currently an employee of BIAL pharmaceutical company. I belong to the medical affairs department of Bial.

The Effects of Iontophoresis in the Treatment of Musculoskeletal Disorders - A Systematic Review and Meta-Analysis

2012 ◽  
Vol 2 (3) ◽  
pp. 180-194
Author(s):  
R. Clijsen ◽  
J. Taeymans ◽  
J. P. Baeyens ◽  
A. O. Barel ◽  
P. Clarys
Keyword(s):  
Systematic Review ◽  
Musculoskeletal Disorders ◽  
Meta Analysis

scholarly journals Workplace Interventions to Reduce Depression and Anxiety in Small and Medium-Sized Enterprises: A Systematic Review

2021 ◽  
Author(s):  
Bridget Hogg ◽  
Joan Carles Medina ◽  
Itxaso Gardoki-Souto ◽  
Ilinca Serbanescu ◽  
Ana Moreno-Alcázar ◽  
...  
Keyword(s):  
Systematic Review ◽  
Depression And Anxiety ◽  
Workplace Interventions

scholarly journals The global summit on the efficacy and effectiveness of spinal manipulative therapy for the prevention and treatment of non-musculoskeletal disorders: a systematic review of the literature

2021 ◽  
Vol 29 (1) ◽  
Author(s):  
Pierre Côté ◽  
Jan Hartvigsen ◽  
Iben Axén ◽  
Charlotte Leboeuf-Yde ◽  
Melissa Corso ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Musculoskeletal Disorders ◽  
Methodological Quality ◽  
Spinal Manipulative Therapy ◽  
Controlled Trials ◽  
Primary Dysmenorrhea ◽  
Review Of The Literature ◽  
Manipulative Therapy ◽  
Randomized Controlled

Abstract Background A small proportion of chiropractors, osteopaths, and other manual medicine providers use spinal manipulative therapy (SMT) to manage non-musculoskeletal disorders. However, the efficacy and effectiveness of these interventions to prevent or treat non-musculoskeletal disorders remain controversial. Objectives We convened a Global Summit of international scientists to conduct a systematic review of the literature to determine the efficacy and effectiveness of SMT for the primary, secondary and tertiary prevention of non-musculoskeletal disorders. Global summit The Global Summit took place on September 14–15, 2019 in Toronto, Canada. It was attended by 50 researchers from 8 countries and 28 observers from 18 chiropractic organizations. At the summit, participants critically appraised the literature and synthesized the evidence. Systematic review of the literature We searched MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, the Cumulative Index to Nursing and Allied Health, and the Index to Chiropractic Literature from inception to May 15, 2019 using subject headings specific to each database and free text words relevant to manipulation/manual therapy, effectiveness, prevention, treatment, and non-musculoskeletal disorders. Eligible for review were randomized controlled trials published in English. The methodological quality of eligible studies was assessed independently by reviewers using the Scottish Intercollegiate Guidelines Network (SIGN) criteria for randomized controlled trials. We synthesized the evidence from articles with high or acceptable methodological quality according to the Synthesis without Meta-Analysis (SWiM) Guideline. The final risk of bias and evidence tables were reviewed by researchers who attended the Global Summit and 75% (38/50) had to approve the content to reach consensus. Results We retrieved 4997 citations, removed 1123 duplicates and screened 3874 citations. Of those, the eligibility of 32 articles was evaluated at the Global Summit and 16 articles were included in our systematic review. Our synthesis included six randomized controlled trials with acceptable or high methodological quality (reported in seven articles). These trials investigated the efficacy or effectiveness of SMT for the management of infantile colic, childhood asthma, hypertension, primary dysmenorrhea, and migraine. None of the trials evaluated the effectiveness of SMT in preventing the occurrence of non-musculoskeletal disorders. Consensus was reached on the content of all risk of bias and evidence tables. All randomized controlled trials with high or acceptable quality found that SMT was not superior to sham interventions for the treatment of these non-musculoskeletal disorders. Six of 50 participants (12%) in the Global Summit did not approve the final report. Conclusion Our systematic review included six randomized clinical trials (534 participants) of acceptable or high quality investigating the efficacy or effectiveness of SMT for the treatment of non-musculoskeletal disorders. We found no evidence of an effect of SMT for the management of non-musculoskeletal disorders including infantile colic, childhood asthma, hypertension, primary dysmenorrhea, and migraine. This finding challenges the validity of the theory that treating spinal dysfunctions with SMT has a physiological effect on organs and their function. Governments, payers, regulators, educators, and clinicians should consider this evidence when developing policies about the use and reimbursement of SMT for non-musculoskeletal disorders.

scholarly journals Zumba®, Fat Mass and Maximum Oxygen Consumption: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 18 (1) ◽  
pp. 105
Author(s):  
Manuel Chavarrias ◽  
Santos Villafaina ◽  
Ana Myriam Lavín-Pérez ◽  
Jorge Carlos-Vivas ◽  
Eugenio Merellano-Navarro ◽  
...  
Keyword(s):  
Systematic Review ◽  
Oxygen Consumption ◽  
Body Mass ◽  
Fat Mass ◽  
Evidence Synthesis ◽  
Meta Analysis ◽  
P Value ◽  
Maximum Oxygen Consumption ◽  
Mass Percentage ◽  
Large Heterogeneity

Background and objectives: Obesity or overweight is associated with many health risk factors and preventable mortality. Even people with normal weight and without history of obesity or overweight should avoid weight gain to reduce health risks factors. In this regard Latin aerobic dances involved in Zumba® practice make this modality motivating for people. Apart from weight loss and VO2peak benefits, Zumba practice is also interesting by the increase in adherence which can also avoid weight regain. The aim was to systematically review the scientific literature about the effects of any randomized intervention of Zumba® practice on total fat mass (%) and maximum oxygen consumption (VO2peak), besides establishing directions for the clinical practice. Evidence acquisition: Two systematic searches were conducted in two electronic databases following the PRISMA guidelines. The eligibility criteria were (a) outcomes: body mass or VO2peak data including mean and standard deviation (SD) before and after Zumba® intervention, (b) study design: randomized controlled trial (RCT) and (c) language: English. GRADE guidelines were used to assess the quality of evidence. A meta-analysis was performed to determine mean differences. Nine and four studies were selected for fat mass percentage and VO2peak in the systematic review, respectively. However, only eight studies for fat mass percentage and three for VO2peak could be included in the meta-analysis. Evidence synthesis: The overall standardized mean difference for fat mass was −0.25 with a 95% CI from −0.67 to 0.16 with a p-value of 0.69, with large heterogeneity. On the other hand, the overall effect size for VO2peak was 0.53 (95% CI from 0.04 to 1.02 with a p-value of 0.03) with large heterogeneity. Conclusions: Based on the evidence, we cannot conclude that Zumba® is effective at reducing body mass but it may improve VO2peak. However, the limited number of studies that met the inclusion criteria makes it too early to reach a definite conclusion, so more research is needed.

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