Effects of Modified Wenjing Decoction Combined with Online Publicity and Education on the Treatment of Primary Dysmenorrhea of Cold Coagulation and Blood Stasis

Objective. To explore the effects of modified Wenjing decoction combined with online publicity and education on the treatment of primary dysmenorrhea of cold coagulation and blood stasis. Methods. The materials of 111 patients with primary dysmenorrhea of cold coagulation and blood stasis in the outpatient department (January 2019–June 2021) were collected to conduct the retrospective study. The 111 patients were randomized into treatment group (n = 59) and control group (n = 52). The control group received online publicity and education and conventional treatment, and the treatment group received online publicity and education and modified Wenjing decoction. The patients in the two groups were continuously treated for three menstrual cycles. The treatment effects, the dosage of analgesics, the scores of associated symptoms before and after treatment, and other indexes were compared between the two groups. Results. The differences in the efficacy on abdominal pain were statistically significant between the two groups P < 0.05 . Compared with the control group, the treatment group had lower scores of associated symptoms after treatment p < 0.5 . After the treatment of three menstrual cycles, 54 patients in the treatment group stopped taking ibuprofen, and the average ibuprofen dosage of the other 5 patients was (0.24 ± 0.16)g. The 52 patients in the control group still needed to take ibuprofen, and the mean dosage was (0.51 ± 0.05)g. The differences in the ibuprofen dosage between the two groups had remarkable difference P < 0.001 . Conclusion. Modified Wenjing decoction combined with online publicity and education can obviously improve the clinical symptoms of the patients with primary dysmenorrhea of cold coagulation and blood stasis and reduce the dosage of analgesics. It is worth promoting and applying in practice.

Pengetahuan dan Sikap Remaja Anak Jalanan tentang Dismenore Primer dan Senam Dismenore di Komunitas Peduli Anak Jalanan Medan

Primary dysmenorrhea is defined as cramping pain in the lower abdomen that occurs at the start of menstruation in the absence of identifiable pelvic disease. It is one of the most common gynecological symptoms among adolescents and adult women with a prevalence of 45%-95%. Overproduction of uterine prostaglandins is the most widely accepted explanation for the pathogenesis. Excessive release of prostaglandins, especially prostaglandin F2 alpha, which is derived from endometrial secretions from menstrual fluid, is believed to cause the condition. Primary dysmenorrhea has different degrees of negative impact on women's physical, psychological and social functioning, which can result in adolescent and adult women being out of school and absent from work. The purpose of this study was to identify the knowledge and attitudes of street children towards primary dysmenorrhea and dysmenorrhea exercise. The research design is descriptive. The sampling technique is total sampling. The number of samples is 45 people. The sample criteria for street children are teenage girls aged 10-18 years, unmarried, already menstruating, can read and write well. Data analysis is descriptive. The results of the study obtained that the majority of street children's knowledge of adolescents was good (53.3%), dysmenorrhea intensity was moderate pain with a score range of 4-7 (68.9%) and adolescent attitudes were negative (71.1%). Knowledge of respondents still needs to be improved to form a positive attitude. It is recommended to the head of KOPA to cooperate with health workers to conduct health education about primary dysmenorrhea on a regular basis to adolescent street children.

Prevalensi dan Gambaran Karakteristik Dismenorea pada Remaja

Background: Dysmenorrhea is a gynecological condition that most commonly occurs in women of childbearing age. Dysmenorrhea is defined as a paiful sensation, cramping in the lower abdoment, and is often accompanied by other symptoms, such as sweating, headache, nausea, vomiting, diarrhea, and shaking. All of this happens right before or during menstruation. Primary dysmenorrhea complaints are often experienced by young women under 25 years old. Dysmenorrhea often results in disruption of activities and social relationships. Pondok Pesantren Putri Ar-Rohmah is a special Islamic boarding school for female students aged 13-18 years. At this age, primary dysmenorrhea complaints often occur. The activities of the students are also very far from the words of heavy activity, they only recite the recitation, memorization and formal schooling which is very lacking in physical activity. Objective: The purpose of this study was to determine the prevalence and description of the characteristics of primary dysmenorrhoea in adolescents at Islamic Boarding School Putri Ar-Rohmah Ngawi. Method: This research was quantitative research with descriptive observational methods. Result: From the study, the prevalence of primary dysmenorrhoea in adolescents in Islamic boarding schools was 83.1%. The highest characteristic of dysmenorrhoea is caused by lack of physical activity, namely 54.2% of respondents are less active and 5.8% of respondents have sedentary behavior. Conclusion: The characteristic description that most influences the occurrence of dysmenorrhoea in students is inadequate physical activity. Meanwhile, the description of the characteristics of body mass index, age of menarche, menstrual cycle, and menstrual duration are not the main characteristics that cause dysmenorrhea in respondents.

Assessment of Primary Dysmenorrhea and Its Effect on the Quality of Life among Female Students at University of Babylon

Primary dysmenorrhea (PD) is a painful menstrual flow in the absence of any pelvic pathology where pain is spasmodic in character and felt mostly in the lower abdominal area. PD considered as common problem in females at reproductive age, it’s directly affects the quality of life (QoL). The main objective of this study is to find out the relationship between PD and QoL of among female students. Descriptive correlational study design carried out on (145) female students, purposive sampling, and their ages between (18–25) years, participants were selected from four faculties at the University of Babylon. Numeric rating pain scale (11-point scale) was used for assessing pain intensity, QoL has been assessed by the SF-36 health survey (SF-36). Data have been collected by using a structured interview as method of data collection and using questionnaire as study tool. Data were processed and analyzed by using SPSS version (25). The findings of the present study revealed that (62.1%) of respondents reported as severe primary dysmenorrhea. The greatest proportion of female students with fair QoL and (17.9%) with poor QoL. The study’s finding finds out a negative significant correlation between PD intensity and overall QoL scale at P ≤ 0.05 (r = − 0.642, P = 0.000).

Comparative Study on Vit. E & Mefenamic acid vs Mefenamic acid alone on mean reduction in pain in Primary Dysmenorrhea

Background: Pelvic pain around the time of mensturation without any identifiable pathologic lesion present from menarche is called primary dysmenorrhea. The pain is believed to be related to prostaglandin (PG). Women with dysmenorrhoea have a relatively high concentration of PGF 2 alpha in menstrual fluid and suppression of PG synthesis has become the main treatment. Aim: To compare mean reduction in pain in patients presenting with primary dysmenorrhea given vitamin E & Mefenamic acid versus Mefenamic acid alone. Results: It was a randomized controlled trial which was conducted in Department of Obstetrics & Gynecology, THQ Raiwind Hospital, Lahore for 6 months duration w.e.f 01/02/2017 to 31/07/2017. In this study, 18(36%) in Vitamin-E group and 21(42%) in Mefenamic acid group were between 15-20 years while 32(64%) in Vitamin-E group and 29(58%) in Mefenamic acid group were between 21-25 years, mean±sd was calculated as 20.86±2.92 and 20.66±2.86 years respectively, mean dysmenorrheal pain at baseline was recorded as 50.06±10.27 in Vitamin-E group and 50.14±10.28 in Mefenamic acid group, p value < 0.754, showing that both groups are insignificant, mean dysmenorrheal pain after treatment was recorded as 20.50±10.04 in Vitamin-E group and 30.22±10.28 in Mefenamic acid group, p value was < 0.002 showing significant difference between the two group, comparison of mean reduction in dysmenorrheal pain after treatment was recorded as 20.56±0.91 in Vitamin-E group and 10.92±0.75 in Mefenamic acid group, p value was < 0.000, showing significant difference. Conclusion: We concluded that there is a significant mean reduction in dysmenorrhic pain in patients given Mefenamic Acid + Vitamen E as compared to patients given Mefenamic Acid alone. Keywords: Dysmenorrhic pain, Mefenamic Acid + Vitamen E, mean reduction in dysmenorrhic pain

Acupuncture for Primary Dysmenorrhea: A Potential Mechanism from an Anti-Inflammatory Perspective

The low adverse effects of acupuncture for primary dysmenorrhea (PD), known as one of the most commonly reported gynecological debilitating conditions affecting women’s overall health, have been thus far confirmed. Moreover, it has been increasingly recognized that inflammation is involved in such menstrual cramps, and recent studies have further shown that the anti-inflammatory effects of acupuncture are helpful in its control. This review portrays the role of inflammation in PD pathophysiology, provides evidence from clinical and animal studies on acupuncture for inflammation-induced visceral pain, and reflects on acupuncture-related therapies for dysmenorrhea with regard to their anti-inflammatory characteristics. Further research accordingly needs to be carried out to clarify the effects of acupuncture on proinflammatory factors in PD, particularly chemokines and leukocytes. Future studies on this condition from an anti-inflammatory perspective should be also performed in line with the notion of emphasizing stimulation modes to optimize the clinical modalities of acupuncture. Additionally, the effects and mechanism of more convenient self-healing approaches such as TENS/TEAS for PD should be investigated.

Efficacy of Guizhi Fuling Wan for primary dysmenorrhea: protocol for a randomized controlled trial

Background Primary dysmenorrhea (PD) is one of the main gynecological complaints in women of child-bearing age, but limited effective treatments are available. Guizhi Fuling Wan (GFW), one of the most widely known traditional Chinese medicine (TCM) formulations, has been commonly used in clinical practice to treat gynecological disorders in China. In recent years, a growing number of studies have shown that GFW is beneficial for patients with PD. However, the quality of evidence is limited, and there are few studies on specific TCM syndromes of GFW for PD. Therefore, we plan to conduct a randomized controlled trial to explore the efficacy and safety of GFW for PD patients with heat-burning blood-stasis syndrome. Methods and analysis The clinical study is a randomized, double-blinded, placebo-controlled trial. Eligible patients will be randomly assigned to the GFW group (treated with GFW) and the control group (treated with a matching placebo) in a 1:1 ratio for three menstrual cycles with a 3-month follow-up. The primary outcome will be the mean change of pain intensity measured by the visual analog scale (VAS). The secondary outcomes will include the Cox Menstrual Symptom Scale (CMSS), the Self-rating Depression Scale (SDS), the Self-rating Anxiety Scale (SAS), and the TCM syndrome scale. Adverse events will also be reported. Discussion This randomized trial will be the first rigorous study designed to assess the efficacy and safety of GFW in treating PD with heat-burning blood-stasis syndrome. The finding of this study will provide an objective clinical basis for the use of GFW for PD in the future. Trial registration Chinese Clinical Trial Registry ChiCTR2000034118. Registered on 24 June 2020