Does Stochasticity Favour Complexity in a Prebiotic Peptide-Micelle System?

2021 ◽  
Author(s):  
Rowena Ball ◽  
John Brindley
Keyword(s):  
Micelle System

PEG-poly(amino acid)s/EpCAM aptamer multifunctional nanoparticles arrest the growth and metastasis of colorectal cancer

2021 ◽  
Author(s):  
Yingru Zhang ◽  
Chunpu Li ◽  
Ru Jia ◽  
Ruixuan Gao ◽  
Yiyang Zhao ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Stem Cells ◽  
Amino Acid ◽  
Cancer Stem Cells ◽  
Drug Release ◽  
Signaling Pathway ◽  
Water Solubility ◽  
Sustained Drug Release ◽  
Colorectal Cancer Stem Cells ◽  
Micelle System

A new nano-micelle system with better water solubility and sustained drug release effect, targeting colorectal cancer stem cells, effectively inhibits the growth and metastasis of colorectal cancer via the Wnt/β-catenin signaling pathway.

Ethylene glycol and the thermostability of trypsin in a reverse micelle system

2006 ◽  
Vol 71 (5) ◽  
pp. 533-537 ◽  
Author(s):  
E. A. Stupishina ◽  
R. N. Khamidullin ◽  
N. N. Vylegzhanina ◽  
D. A. Faizullin ◽  
Yu. F. Zuev
Keyword(s):  
Ethylene Glycol ◽  
Reverse Micelle ◽  
Micelle System

scholarly journals Bombesin-Tethered Reactive Oxygen Species (ROS)-Responsive Nanoparticles for Monomethyl Auristatin F (MMAF) Delivery

2021 ◽  
Vol 8 (4) ◽  
pp. 43
Author(s):  
Jihoon Kim ◽  
Jee Seon Kim ◽  
Kyung Hyun Min ◽  
Young-Hwa Kim ◽  
Xiaoyuan Chen
Keyword(s):  
Blood Circulation ◽  
Burst Release ◽  
Oxygen Species ◽  
Antibody Drug Conjugate ◽  
Gastrin Releasing Peptide ◽  
Anticancer Effects ◽  
Efficient Delivery ◽  
Nanoparticle System ◽  
Micelle System

Dolastatin derivatives, represented by monomethylauristatin E (MMAE), have been translated in clinic with a form of antibody–drug conjugate; however, their potential in nanoparticle systems has not been well established due to the potential risk of immature release of extremely high cytotoxic dolastatin drugs during blood circulation. Herein, we rationally propose monomethylauristatin F (MMAF), a dolastatin-derived, loaded nanoparticle system composed of bombesin (BBN)-tethered ROS-responsive micelle system (BBN-PEG-PPADT) to achieve efficient anticancer therapy with targeted and efficient delivery of MMAF. The developed MMAF-loaded BBN-PEG-PPADT micelles (MMAF@BBN-PEG-PPADT) exhibited improved cellular uptake via interactions between BBN and gastrin-releasing peptide receptors on the cancer cells and the intracellular burst release of MMAF, owing to the ROS-responsive disruption, which allowed the efficient anticancer effects of MMAF in vitro. This study suggests the potential of nanoparticle systems in the delivery of dolastatin drugs.

scholarly journals In vivo antileishmanial efficacy of a naphthoquinone derivate incorporated into a Pluronic® F127-based polymeric micelle system against Leishmania amazonensis infection

2019 ◽  
Vol 109 ◽  
pp. 779-787 ◽  
Author(s):  
Débora V.C. Mendonça ◽  
Grasiele S.V. Tavares ◽  
Daniela P. Lage ◽  
Tauane G. Soyer ◽  
Lívia M. Carvalho ◽  
...  
Keyword(s):  
Polymeric Micelle ◽  
Leishmania Amazonensis ◽  
Micelle System

Materializing sequential killing of tumor vasculature and tumor cells via targeted polymeric micelle system

2011 ◽  
Vol 149 (3) ◽  
pp. 299-306 ◽  
Author(s):  
Yiguang Wang ◽  
Tingyuan Yang ◽  
Xun Wang ◽  
Wenbing Dai ◽  
Jiancheng Wang ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Tumor Vasculature ◽  
Polymeric Micelle ◽  
Micelle System

Indirect electrolytic reduction of 2 nitro-m-xylene to 2 amino-m-xylene in micelle system

1980 ◽  
Vol 25 (8) ◽  
pp. 1083-1084 ◽  
Author(s):  
M. Noel ◽  
P.N. Anantharaman ◽  
H.V.K. Udupa
Keyword(s):  
Electrolytic Reduction ◽  
Micelle System

scholarly journals The Interaction of Methylene Blue and Bovine Serum Albumin in SDS Micelle System

2001 ◽  
Vol 17 (02) ◽  
pp. 185-188 ◽  
Author(s):  
Guo Rong ◽  
◽  
Fan Guo-Kang ◽  
Liu Tian-Qing ◽  
Jiao Xin-An
Keyword(s):  
Methylene Blue ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Sds Micelle ◽  
Micelle System

Surface protection of an organic pigment based on a modification using a mixed-micelle system

2016 ◽  
Vol 127 ◽  
pp. 100-109 ◽  
Author(s):  
Erika Švara Fabjan ◽  
Mojca Otoničar ◽  
Miran Gaberšček ◽  
Andrijana Sever Škapin
Keyword(s):  
Mixed Micelle ◽  
Organic Pigment ◽  
Surface Protection ◽  
Micelle System
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