Adherence with perindopril therapy: a pilot study using therapeutic drug monitoring of perindoprilat and an evaluation of the clearance estimation

2017 ◽  
Vol 39 (5) ◽  
pp. 1095-1100 ◽  
Author(s):  
Martin Šíma ◽  
Martin Vodička ◽  
Věra Marešová ◽  
Tomáš Šálek ◽  
Radomír Čabala ◽  
...  
Keyword(s):  
Pilot Study ◽  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Therapeutic Drug

scholarly journals The Possibility of Therapeutic Drug Monitoring of the Most Important Interactions in Nursing Homes

2019 ◽  
Vol 14 (2) ◽  
pp. 152-156 ◽  
Author(s):  
Pernille Schjøtt ◽  
Martina Šutovská ◽  
Jan Schjøtt
Keyword(s):  
Clinical Pharmacology ◽  
Pilot Study ◽  
Therapeutic Drug Monitoring ◽  
Nursing Homes ◽  
Elderly Patients ◽  
Drug Monitoring ◽  
Therapeutic Drug ◽  
Important Interaction ◽  
Potential Interactions ◽  
Recommended Action

Background:Therapeutic drug monitoring is a relevant tool in drug treatment of elderly patients. The aim of this study was to assess the possibility of therapeutic drug monitoring of the most important potential interactions in nursing homes.Methods:A material of prescribed drugs to 446 patients in three nursing homes in Bergen, Norway from a single day in March 2016 was analysed. Clinically relevant drug interactions (pharmacodynamic or pharmacokinetic) were identified and classified with Stockley`s Interaction Alerts. The most important interaction among several in each patient were ranked by recommended action > severity > evidence according to Stockley`s. The possibility of therapeutic drug monitoring of drug combinations involved in the most important interactions was retrieved from a database of all laboratories performing clinical pharmacology in Norway (the Pharmacology Portal).Results:Two or more drugs were used by 443 (99.3%) of 446 patients. Three-hundred and eightyfour patients (86.1%) had > 1 interaction. About 95% of the most important interactions were pharmacodynamic. In 280 (72.9%) of these interactions, Stockley`s recommended adjust dose or monitoring. Among the 384 most important interactions, 93% involved one drug and 41% involved two drugs available for therapeutic drug monitoring.Conclusion:In this pilot study, therapeutic drug monitoring was possible in the majority of the most important interactions in Norwegian nursing homes. This option is of importance since adjust dose or monitoring were frequently recommended actions associated with these interactions.

Therapeutic drug monitoring of olanzapine in children and adolescents with anorexia nervosa: A pilot study

2012 ◽  
Vol 45 (06) ◽  
Author(s):  
S Bangratz ◽  
M Moyses ◽  
S Mader ◽  
J Huemer ◽  
D Koubek ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Pilot Study ◽  
Therapeutic Drug Monitoring ◽  
Children And Adolescents ◽  
Drug Monitoring ◽  
Therapeutic Drug

scholarly journals A Pilot Study to Evaluate the Role of Therapeutic Drug Monitoring of Pegfilgrastim in Lymphoma Patients Receiving Chemotherapy

2014 ◽  
Vol 23 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Michelle See ◽  
Vivianne Lee Chuen Shih ◽  
Han Kiat Ho ◽  
Tiffany Pooi Ling Tang ◽  
Mohamad Farid ◽  
...  
Keyword(s):  
Pilot Study ◽  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Therapeutic Drug
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