scholarly journals Quality of life in patients with type 2 diabetes after switching to insulin degludec: results from a cross-sectional survey

Author(s):  
Chioma Uzoigwe ◽  
Michael Radin ◽  
Carol M. Hamersky ◽  
Mitch DeKoven ◽  
Cassie Holt ◽  
...  

Abstract Purpose Five quality of life (QoL) domains are particularly important to patients with type 2 diabetes (T2D) using basal insulin—sense of physical well-being, sense of safety regarding hypoglycemia, sense of diabetes as burdensome, feelings of freedom and flexibility, and sleep quality. Methods An online survey assessed these QoL domains in adult patients with T2D in the USA who had switched from a previous basal insulin to insulin degludec (IDeg): modified versions of the World Health Organization (Five) Well-Being Index (WHO-5), Hypoglycemia Attitudes and Behavior Scale (HABS; confidence and anxiety subscales only), and Diabetes Distress Scale (DDS; emotional burden and regimen-related distress subscales only); three items assessing feelings of freedom and flexibility; and one item assessing sleep quality (hours of restful sleep). Patients rated each item for their previous basal insulin and currently while using IDeg. Correlations between sleep quality and the other QoL scales were also assessed. Results In total, 152 patients completed the survey and were included in the study sample. Patients reported significantly improved scores while using IDeg on all WHO-5, DDS, HABS, feelings of freedom and flexibility item scores, and total raw/mean subscale scores (P < 0.0001). Patients also reported a significantly greater number of hours of restful sleep [mean (SD) 6.6 (2.0) vs. 5.5 (1.8); P < 0.0001]. Better sleep quality statistically significantly correlated with improved QoL in all other domains assessed. Conclusions Treatment with IDeg after switching from a previous basal insulin was associated with statistically significant improvements in all QoL domains assessed.

2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Margaret Amankwah‐Poku ◽  
Josephine Akpalu ◽  
Araba Sefa‐Dedeh ◽  
Albert G. B. Amoah

2021 ◽  
Vol 11 (22) ◽  
pp. 11046
Author(s):  
Han-Hung Huang ◽  
Brianna Gathright ◽  
Rachel Holik ◽  
Hannah Iverson ◽  
Emily Saville ◽  
...  

The objective of this study was to assess the effects of an active video game (AVG) program in physiological parameters, fitness levels, motivation to physical activity, and quality of life on people with type 2 diabetes (T2D). Eight T2D patients participated in the 8-week AVG program using Xbox Kinect and/or Nintendo Wii. Heart rate (HR) and rating of perceived exertion (RPE) were monitored during exercise. Physiological and fitness assessment included hemoglobin A1C (HbA1c), HR, blood pressure (BP), body mass index, body composition, aerobic and muscular endurance, muscular strength, and flexibility. Psychological outcome measures included the Physical Activity Measure-Revised (MPAM-R), Situational Motivation Scale (SIMS), and World Health Organization Quality of Life (WHOQOL)-BREF. Participants demonstrated a moderate level of exercise intensity during AVG based on average HR and RPE. HbA1c, BP, and lower extremity muscle strength were improved, but were not statistically significant. The changes on psychological assessment were not significant. However, most participants demonstrated positive behavior and attitudes toward health and physical activity at one-month follow-up. This pilot study demonstrated that the AVG program might be an effective and alternative way of exercise for people with T2D. A future RCT is warranted to determine the physical and psychological effects of AVG on T2D population.


Author(s):  
Hardesh Dhillon ◽  
Rusli Bin Nordin ◽  
Amutha Ramadas

Diabetes complications, medication adherence, and psychosocial well-being have been associated with quality of life (QOL) among several Western and Asian populations with diabetes, however, there is little evidence substantiating these relationships among Malaysia’s unique and diverse population. Therefore, a cross-sectional study was conducted in a Malaysian public primary care clinic among 150 patients diagnosed with type 2 diabetes mellitus (T2DM). Structured and validated questionnaires were used to investigate the associations between demographic, clinical, and psychological factors with QOL of the study participants. Approximately three-quarters of patients had a good-excellent QOL. Diabetes-related variables that were significantly associated with poor QOL scores included insulin containing treatment regimens, poor glycemic control, inactive lifestyle, retinopathy, neuropathy, abnormal psychosocial well-being, higher diabetes complication severity, and nonadherence (p < 0.05). The main predictors of a good-excellent QOL were HbA1c ≤ 6.5% (aOR = 20.78, 95% CI = 2.5175.9, p = 0.005), normal anxiety levels (aOR = 5.73, 95% CI = 1.8–18.5, p = 0.004), medication adherence (aOR = 3.35, 95% CI = 1.3–8.7, p = 0.012), and an aDCSI score of one and two as compared to those greater than or equal to four (aOR = 7.78, 95% CI = 1.5–39.2, p = 0.013 and aOR = 8.23, 95% CI = 2.1–32.8, p = 0.003), respectively. Medication adherence has also been found to be an effect modifier of relationships between HbA1c, depression, anxiety, disease severity, and QOL. These predictors of QOL are important factors to consider when managing patients with T2DM.


2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Petros Katsogiannos ◽  
Eva Randell ◽  
Magnus Sundbom ◽  
Andreas Rosenblad ◽  
Jan W. Eriksson ◽  
...  

Abstract Background To examine the effects of gastric bypass surgery on health-related quality of life (HRQoL) in obese patients with type 2 diabetes, and to investigate their experiences of life adjustments using quantitative and qualitative methods. Methods Thirteen patients with type 2 diabetes and obesity, (body mass index, BMI > 30 kg/m2), participating in a randomized clinical trial, completed this sub-study. HRQoL was evaluated before, and at 6 months and 2 years after gastric bypass surgery, using the RAND- 36-item health survey. At 2 years, interviews for in-depth analysis of HRQoL changes were performed. Results Significant improvement was observed from baseline to 6 months for 2 of the eight health concepts, general health, and emotional well-being. At 2 years, improvements were also seen in physical functioning, energy/fatigue, as well as sustained improvements in general health and emotional well-being. Multiple regression analyses showed mostly non-significant associations between the magnitude of decrease in weight, BMI, and HbA1c during follow-up and improvement in HRQoL. The analyses from qualitative interviews supported a common latent theme “Finding a balance between the experience of the new body weight and self-confidence”. Conclusions The improved HRQoL after gastric bypass surgery in obese patients with type 2 diabetes was not explained specifically by the magnitude of weight loss, but rather by the participants achieving a state of union between body and consciousness. Trial registration ClinicalTrials.gov Identifier NCT02729246. Date of registration 6 April 2016 – Retrospectively registered https://clinicaltrials.gov/ct2/show/NCT02729246?term=bariglykos&draw=2&rank=1


2021 ◽  
Vol 31 (1) ◽  
pp. 61-67
Author(s):  
Faezeh Jahan ◽  
◽  
Saeed Nematolahi ◽  

Introduction: Diabetes is a chronic disease with fatal health complications. Identifying the psychological factors that control this disease is very important, one of which is quality of life (QOL). Objective: This study aimed to investigate the effect of a QOL education program on psychological well-being (PWB) and adherence to treatment of patients with type 2 diabetes. Materials and Methods: This is a pilot study with a quasi-experimental design based on pretest and posttest phases. The statistical population consists of all diabetic patients referred to health centers in Semnan City, Iran during the 6months from March to September 2018.Of them,30 type 2 diabetes, aged 30-60 years (male and female) were selected based on the inclusion criteria and randomly assigned to the intervention and control groups. They were first assessed by using Hayes’s general adherence scale (GAS) and Ryff’s psychological well-being scale the short form (PWBS-SF).Then, the intervention group received QOL education in 12 sessions, once per week each for 90 min. Then, posttest assessments were carried out. The collected data were analyzed using MANCOVA. Results: The QOL education program significantly increased adherence to treatment (P= 0.005) and PWV and all its dimensions (autonomy, environmental mastery, personal growth, positive relations with others, be purposeful in life, self-acceptance) in patients (P = 0.005). Conclusion: Since diabetes is one of the chronic diseases that need constant care and there is no definitive and immediate treatment for it, increasing PWB and adherence to treatment in patients to control this disease by QOL education can be very effective.


2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Kidist Reba ◽  
Bizuayehu Walle Birhane ◽  
Hordofa Gutema

Background. Although it is largely preventable, type 2 diabetes is the most common type and accounts for the vast majority of diabetes cases worldwide. Objective. To assess the validity and reliability of the Amharic version of the abbreviated World Health Organization Quality of Life (WHOQOL-BREF) instrument for measuring quality of life in people with diagnosed type 2 diabetes. Methods. The Amharic version of the abbreviated World Health Organization Quality of Life instrument was administered to 344 patients with diagnosed type 2 diabetes in Felege Hiwot Referral Hospital. Contribution of domain scores to QOL facets was assessed using multiple linear regression. Reliability assessment was done by using Cronbach’s alpha coefficient. Construct validity was examined using exploratory and confirmatory factor analyses. Result. The Amharic version of the abbreviated World Health Organization Quality of Life instrument has acceptable internal consistency. Confirmatory factor analysis has shown acceptable goodness of fit for 4 domain models. The physical, psychological, and environmental domains have a statistically significant contribution in explaining overall quality of life, while only physical and psychological domains have significant contribution in explaining the general health facet. Conclusion. The Amharic version of the abbreviated World Health Organization Quality of Life instrument is appropriate for patients with diagnosed type 2 diabetes. The overall finding of analysis implies that the Amharic version of the abbreviated World Health Organization Quality of Life instrument has internal consistency and validity to investigate quality of life among patients with diagnosed type 2 diabetes, and it can be used for studies which are going to be conducted in Ethiopia.


2011 ◽  
Vol 37 (3) ◽  
pp. 347-355 ◽  
Author(s):  
Faith S. Luyster ◽  
Jacqueline Dunbar-Jacob

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