scholarly journals Magnetic resonance elastography (MRE) shows significant reduction of thigh muscle stiffness in healthy older adults

GeroScience ◽  
2019 ◽  
Vol 42 (1) ◽  
pp. 311-321 ◽  
Author(s):  
Paul Kennedy ◽  
Eric Barnhill ◽  
Calum Gray ◽  
Colin Brown ◽  
Edwin J.R. van Beek ◽  
...  
Keyword(s):  
Older Adults ◽  
Magnetic Resonance ◽  
Vastus Lateralis ◽  
Rectus Femoris ◽  
Magnetic Resonance Elastography ◽  
Muscle Stiffness ◽  
Thigh Muscle ◽  
Cross Sectional ◽  
Healthy Older Adults ◽  
Fat Fraction

AbstractDetermining the effect of ageing on thigh muscle stiffness using magnetic resonance elastography (MRE) and investigate whether fat fraction and muscle cross-sectional area (CSA) are related to stiffness. Six healthy older adults in their eighth and ninth decade and eight healthy young men were recruited and underwent a 3 T MRI protocol including MRE and Dixon fat fraction imaging. Muscle stiffness, fat fraction and muscle CSA were calculated in ROIs corresponding to the four quadriceps muscles (i.e. vastus lateralis (VL), vastus medialis (VM), vastus intermedius (VI), rectus femoris (RF)), combined quadriceps, combined hamstrings and adductors and whole thigh. Muscle stiffness was significantly reduced (p < 0.05) in the older group in all measured ROIs except the VI (p = 0.573) and RF (p = 0.081). Similarly, mean fat fraction was significantly increased (p < 0.05) in the older group over all ROIs with the exception of the VI (p = 0.059) and VL muscle groups (p = 0.142). Muscle CSA was significantly reduced in older participants in the VM (p = 0.003) and the combined quadriceps (p = 0.001), hamstrings and adductors (p = 0.008) and whole thigh (p = 0.003). Over the whole thigh, stiffness was significantly negatively correlated with fat fraction (r = − 0.560, p = 0.037) and positively correlated with CSA (r = 0.749, p = 0.002). Stepwise regression analysis revealed that age was the most significant predictor of muscle stiffness (p = 0.001). These results suggest that muscle stiffness is significantly decreased in healthy older adults. Muscle fat fraction and muscle CSA are also significantly changed in older adults; however, age is the most significant predictor of muscle stiffness.

scholarly journals High-resolution magnetic resonance elastography reveals differences in subcortical gray matter viscoelasticity between young and healthy older adults

2018 ◽  
Vol 65 ◽  
pp. 158-167 ◽  
Author(s):  
Lucy V. Hiscox ◽  
Curtis L. Johnson ◽  
Matthew D.J. McGarry ◽  
Michael Perrins ◽  
Aimee Littlejohn ◽  
...  
Keyword(s):  
Older Adults ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Gray Matter ◽  
Magnetic Resonance Elastography ◽  
Healthy Older Adults

scholarly journals Sonoelastography to Assess Muscular Stiffness Among Older Adults and its Use for the Diagnosis of Sarcopenia: A Systematic Review

2020 ◽  
Author(s):  
Ewa Magdalena Janczyk ◽  
Noémie Champigny ◽  
Emeline Michel ◽  
Charles Raffaelli ◽  
Cédric Annweiler ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Older Patients ◽  
Shear Wave Elastography ◽  
Rectus Femoris ◽  
Muscle Stiffness ◽  
Cross Sectional ◽  
Significant Difference ◽  
Independent Review ◽  
Cross Sectional Design

AbstractChanges in muscle stiffness have been reported with sarcopenia. Sonoelastography is an accessible and non-radiating imaging technique allowing quantification of elastic properties of tissue. We performed a systematic review of the literature to investigate whether sonoelastography can be a reliable method to assess sarcopenia in older patients. We searched Medline, Google Scholar, Scopus, SpringerLink and Science direct from January 1, 1990 to April 1, 2020. Three independent review authors assessed trial eligibility, extracted the data, and assessed risk of bias. We intended to learn which types of elastography have been tested, if such measures are repeatable, and if they have been compared to the currently accepted diagnostic method. Ten studies met the inclusion criteria. Most followed a cross-sectional design with young and older adult subgroups. The gastrocnemius, rectus femoris, and vastus intermedius appeared most frequently. Nine of the included studies used shear wave elastography and one-strain elastography. The passive elastic constant was significantly greater in sarcopenic versus healthy subjects after passive stretching (124.98 ± 60.82 vs. 46.35 ± 15.85, P = 0.004). However, even in non-sarcopenic patients, the age of the patient was responsible for about 45.5 % of the variance in SWV. Among ten included articles, four reported higher stiffness in the muscles of older adults, two reported lower stiffness, and four found no significant difference. Due to the substantial heterogenicity of actual data, we could not make any conclusions about the potential usefulness of elastography to assess sarcopenia. Further studies are needed, including a larger sample of older patients and using a standardized and reproducible protocol.

Mechanical behavior of the quadriceps femoris muscle tendon unit during low-load contractions

2008 ◽  
Vol 104 (5) ◽  
pp. 1320-1328 ◽  
Author(s):  
Taija Finni ◽  
Marko Havu ◽  
Shantanu Sinha ◽  
Jussi-Pekka Usenius ◽  
Sulin Cheng
Keyword(s):  
Vastus Lateralis ◽  
Single Point ◽  
Frontal Plane ◽  
Muscle Thickness ◽  
Rectus Femoris ◽  
Quadriceps Femoris ◽  
Thigh Muscle ◽  
Cross Sectional ◽  
Quadriceps Femoris Muscle ◽  
Femoris Muscle

We examined the relationships between morphology and muscle-tendon dynamics of the quadriceps femoris muscle of 11 men using velocity-encoded phase-contrast magnetic resonance imaging (MRI). Thigh muscle electromyography and joint range of motion were first measured outside the MRI scanner during knee extension-flexion tasks that were performed at a rate of 40 times/min with elastic bands providing peak resistance of 5.2 kp (SD 0.4) to the extension. The same movement was repeated inside the MRI scanner bore where tissue velocities and muscle morphology were recorded. The average displacement in the proximal and distal halves of the rectus femoris and vastus intermedius aponeuroses was different ( P = 0.049), reflecting shortening (1.6%), but the tensile strain along the length of the aponeuroses was uniform. The aponeurosis behavior varied among individuals, and these individual patterns were best explained by the differences in relative cross-sectional area of rectus femoris to vastus muscles ( r = 0.71, P = 0.014). During dynamic contraction, considerable deformation of muscles in the axial plane caused an anatomic measure such as muscle thickness to change differently (decrease or increase) in different sites of measurement. For example, when analyzed from the axial images, the vastus lateralis thickness did not change ( P = 0.946) in the frontal plane through femur but increased in a 45° oblique plane between the frontal and sagittal planes ( P = 0.004). The present observations of the heterogeneity and individual behavior emphasize the fact that single-point measurements do not always reflect the overall behavior of muscle-tendon unit.

scholarly journals Determination of thigh muscle stiffness using magnetic resonance elastography

2006 ◽  
Vol 23 (2) ◽  
pp. 242-247 ◽  
Author(s):  
Sabine F. Bensamoun ◽  
Stacie I. Ringleb ◽  
Laurel Littrell ◽  
Qingshan Chen ◽  
Michael Brennan ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Elastography ◽  
Muscle Stiffness ◽  
Thigh Muscle

Analysis of thigh muscle stiffness from childhood to adulthood using magnetic resonance elastography (MRE) technique

2011 ◽  
Vol 26 (8) ◽  
pp. 836-840 ◽  
Author(s):  
Laëtitia Debernard ◽  
Ludovic Robert ◽  
Fabrice Charleux ◽  
Sabine F. Bensamoun
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Elastography ◽  
Muscle Stiffness ◽  
Thigh Muscle

scholarly journals Hippocampal viscoelasticity and episodic memory performance in healthy older adults examined with magnetic resonance elastography

2018 ◽  
Vol 14 (1) ◽  
pp. 175-185 ◽  
Author(s):  
Lucy V. Hiscox ◽  
Curtis L. Johnson ◽  
Matthew D. J. McGarry ◽  
Hillary Schwarb ◽  
Edwin J. R. van Beek ◽  
...  
Keyword(s):  
Older Adults ◽  
Magnetic Resonance ◽  
Episodic Memory ◽  
Memory Performance ◽  
Magnetic Resonance Elastography ◽  
Healthy Older Adults

scholarly journals Thigh muscle stiffness assessed with magnetic resonance elastography in hyperthyroid patients before and after medical treatment

2007 ◽  
Vol 26 (3) ◽  
pp. 708-713 ◽  
Author(s):  
Sabine F. Bensamoun ◽  
Stacie I. Ringleb ◽  
Qingshan Chen ◽  
Richard L. Ehman ◽  
Kai-Nan An ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Medical Treatment ◽  
Magnetic Resonance Elastography ◽  
Muscle Stiffness ◽  
Thigh Muscle ◽  
Before And After ◽  
Hyperthyroid Patients

scholarly journals Exercise Snacking to Improve Muscle Function in Healthy Older Adults: A Pilot Study

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Oliver J. Perkin ◽  
Polly M. McGuigan ◽  
Keith A. Stokes
Keyword(s):  
Older Adults ◽  
Pilot Study ◽  
Body Mass ◽  
Muscle Function ◽  
Exercise Intervention ◽  
Muscle Size ◽  
Thigh Muscle ◽  
Activity Levels ◽  
Cross Sectional ◽  
Healthy Older Adults

Loss of muscle mass and strength are seemingly accepted as part of the ageing process, despite ultimately leading to the loss of independence. Resistance exercise is considered to be primary defence against loss of muscle function in older age, but it typically requires access to exercise equipment often in a gym environment. This pilot study aimed at examining the effect of a 28-day, unsupervised home-based exercise intervention on indices of leg strength and muscle size in healthy older adults. Twenty participants were randomly assigned to either maintain their habitual physical activity levels (Control; n=10; age, 74 (5) years; body mass, 26.3 (3.5) kg/m2) or undertake “exercise snacks” twice daily (ES; n=10; age, 70 (4) years; body mass, 25.0 (3.4) kg/m2). Both groups consumed 150 g of yogurt at their breakfast meal for the duration of the intervention. Sixty-second sit-to-stand score improved by 31% in ES, with no change in Control (p<0.01). Large effect sizes were observed for the difference in change scores between the groups for interpolated maximum leg pressing power (6% increase in ES) and thigh muscle cross-sectional area (2% increase in ES). The present pilot data suggest that exercise snacking might be a promising strategy to improve leg muscle function and size in older adults and that further investigation into zero-cost exercise strategies that allow high frequency of training is warranted.

scholarly journals Muscle Activation and Kinematic Analysis during the Inclined Leg Press Exercise in Young Females

2020 ◽  
Vol 17 (22) ◽  
pp. 8698
Author(s):  
Isabel Martín-Fuentes ◽  
José M. Oliva-Lozano ◽  
José M. Muyor
Keyword(s):  
Muscle Activation ◽  
External Rotation ◽  
Vastus Lateralis ◽  
Maximum Velocity ◽  
Rectus Femoris ◽  
Thigh Muscle ◽  
Vastus Medialis ◽  
Cross Sectional ◽  
Female Population ◽  
Leg Press

Knee joint muscle activation imbalances, especially weakness in the vastus medialis oblique, are related to patellofemoral pain within the female population. The available literature presents the leg press as an exercise which potentially targets vastus medialis oblique activation, thus reducing imbalances in the quadriceps muscles. The main aim of the present study was to compare thigh muscle activation and kinematic parameters under different conditions during the inclined leg press exercise in a young female population. A cross-sectional study was conducted on 10 young, trained females. Muscle activation of the vastus medialis oblique, vastus lateralis, rectus femoris and gluteus medialis was analyzed under five different inclined leg press conditions, modifying the feet rotation (0–45° external rotation) and the stance width (100–150% hip width) on the footplate. All the conditions were performed at two different movement velocities: controlled velocity (2″ eccentric–2″ concentric) and maximal intended velocity. Mean propulsive velocity, maximum velocity and maximum power were also assessed. The results show that both controlled velocity conditions and maximal intended velocity conditions elicited a similar muscle activation pattern with greater activation during the concentric phase (p < 0.001, ηp2 = 0.96). The maximal intended velocity conditions showed greater overall muscle activation (p < 0.001, ηp2 = 0.91). The vastus medialis oblique presented the greatest muscle activation, followed by the rectus femoris, vastus lateralis and, the gluteus medialis. Furthermore, the inclined leg press condition with 0º feet rotation, 100% hip width distance and the maximal intended velocity generated the greatest kinematic parameter outputs. In conclusion, the inclined leg press exercise might be an optimal exercise to target vastus medialis activation regardless of the feet rotation and stance width conditions.

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