Assessment of the antibacterial activity of phenylethanoid glycosides from Phlomis lanceolata against multiple-drug-resistant strains of Staphylococcus aureus

2007 ◽  
Vol 62 (1) ◽  
pp. 91-95 ◽  
Author(s):  
Hossein Nazemiyeh ◽  
M. Mukhlesur Rahman ◽  
Simon Gibbons ◽  
Lutfun Nahar ◽  
Abbas Delazar ◽  
...  
2015 ◽  
Vol 5 ◽  
pp. S151-S154
Author(s):  
Rafiqul Islam ◽  
Md. Shahedur Rahman ◽  
Riad Hossain ◽  
Nazmun Nahar ◽  
Belal Hossin ◽  
...  

1981 ◽  
Vol 34 (3) ◽  
pp. 305-312 ◽  
Author(s):  
MASAMI TSUCHIYA ◽  
KAYOKO SUZUKAKE ◽  
MAKOTO HORI ◽  
TSUTOMU SAWA ◽  
TOMIO TAKEUCHI ◽  
...  

2016 ◽  
Vol 5 (03) ◽  
pp. 4879
Author(s):  
Srikala Ganapathy* ◽  
Karpagam S.

Rise of antibiotic resistant pathogenic bacteria namely Methicillin Resistant Staphylococcus aureus (MRSA) and Multiple drug resistant Escherichia coli (MDR E. coli results in reduced efficacy of currently used antibacterial agents. Medicinal plants serve as potential targets for biologically effective antibacterial agents. The present study determined the phytochemical and invitro antibacterial activity of ethanol, chloroform, hexane and water extracts of whole plant of Andrographis paniculata against MRSA and MDR Escherichia coli. Zone of inhibition diameters were measured. Compared to all the extracts, ethanolic extract showed highest activity. The antibacterial activity was absent in hexane and water extracts. Chloroform extracts showed moderately good activity. The antibacterial compounds found in ethanolic extract were flavanoids, saponins and alkaloids.


2019 ◽  
Vol 19 (1) ◽  
pp. 7-20 ◽  
Author(s):  
Prakhar Srivastava ◽  
Karthikeyan Sivashanmugam

Diabetic foot ulcer (DFU) is a major complication of diabetes mellitus, major observations of DFU cases have reported on amputation of foot region, and microbial bioburden during DFU is a major cause that affects healing of the wound regions. Pathogenic microbes are routinely isolated from these wound regions, especially Staphylococcus, Pseudomonas, Klebsiella, and Escherichia coli have been reported, whereas higher prevalence of Pseudomonas species during chronic condition in the deeper part of the wound, when left untreated, leads to gangrene. Multiple drug-resistant Pseudomonas strains are a new threat because of their biofilm-forming ability, making it more potent and incurable. Acyl homoserine lactones (AHL) are a group of signaling molecules that can regulate biofilm growth, and Las and Rhl operon generally work in tandem to initiate biofilm formation by Pseudomonas species. These signaling molecules also initiate virulence factors that correlates upregulation of inflammatory responses, and AHL can be a therapeutic target in order to prevent the efficacy of multiple drug-resistant strains that form biofilm and also can be an alternative solution against control of multiple drug-resistant strains.


Sign in / Sign up

Export Citation Format

Share Document