ANTIBACTERIAL ACTIVITY OF BIOSYNTHESIZED SILVER NANOPARTICLES FROM VIOLA SERPENS AGAINST MULTI DRUG RESISTANT STRAINS OF STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA

2017 ◽  
pp. 1379-1393
Author(s):  
Anu Kumar
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Drug Resistant ◽  
Resistant Strains ◽  
Drug Resistant Strains

scholarly journals Study of bacterial pathogens causing chronic suppurative otitis media and the antibiotic susceptibility pattern of the isolates at a tertiary care centre in Kochi

2020 ◽  
Vol 6 (4) ◽  
pp. 714
Author(s):  
Geetha Nair ◽  
Tanya Tonny Mampilly ◽  
Bindhu Vasudevan ◽  
J. Lancy
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Tertiary Care ◽  
Drug Resistant ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Suppurative Otitis Media ◽  
Resistant Strains ◽  
Drug Resistant Strains

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is defined as chronic inflammation of middle ear and mastoid cavity presenting with recurrent ear discharges through a tympanic membrane perforation. Complications of CSOM were frequent in pre-antibiotic era. Injudicious use of antibiotics led to the emergence of multi-drug resistant strains and complications in return. To isolate the organisms associated with CSOM in a tertiary care centre and to detect their antibiogram.</p><p class="abstract"><strong>Methods:</strong> In this clinical, prospective, cross sectional study, a total of 100 patients clinically diagnosed with CSOM were enrolled from January to December 2019 (1 year).  </p><p class="abstract"><strong>Results:</strong> Of the 100 samples collected, predominant bacteria were isolated in 58 patients (58%). The most common isolate was <em>Pseudomonas aeruginosa</em> (29 isolates) followed by <em>Staphylococcus aureus</em> (24), <em>Klebsiella</em> species (3) and 1 isolate each of <em>Pneumococci</em> and <em>Acinetobacter</em> species. Among the 29 isolates of <em>Pseudomonas aeruginosa</em>, 8 (28%) were multidrug resistant. Sensitivity was 100% to imipenem followed by 97% to meropenem,79% to gentamicin, 76% to amikacin, 66% to ciprofloxacin, 41% to piperacillin tazobactam and 17% to ceftazidime. Of the 24 isolates of <em>Staphylococcus aureus</em>, 4 (16%) were methicillin resistant <em>Staphylococcus aureus</em> (MRSA).</p><p class="abstract"><strong>Conclusions:</strong> Pseudomonas aeruginosa was the most common isolate, of which 28% were multi drug resistant. This calls for the judicious use of antibiotics and alternative measures for treatment of drug resistant strains. Formulating an antibiotic policy based on the local antibiogram can help in preventing the emergence and spread of resistant pathogens.</p>

Piperazinyl-linked fluoroquinolone dimers possessing potent antibacterial activity against drug-resistant strains of Staphylococcus aureus

2003 ◽  
Vol 13 (10) ◽  
pp. 1745-1749 ◽  
Author(s):  
Robert J. Kerns ◽  
Michael J. Rybak ◽  
Glenn W. Kaatz ◽  
Flamur Vaka ◽  
Raymond Cha ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Drug Resistant ◽  
Resistant Strains ◽  
Drug Resistant Strains

scholarly journals SCREENING PHYTOCHEMICAL AND ANTI-METHICILLIN RESISTANT (MRSA) ACTIVITY OF 70 % ETHANOLIC EXTRACT FROM THE STEM BARK OF ALBIZIA LEBBECK(L.) BENTH.(FABACEAE)

2018 ◽  
Vol 6 (6) ◽  
pp. 1-6
Author(s):  
Yao KANGA ◽  
CAMARA Djeneb ◽  
KOUASSI Kouadio Aubin ◽  
ZIRIHI Guédé Noël
Keyword(s):  
Antibacterial Activity ◽  
Reference Strain ◽  
Ethanolic Extract ◽  
Stem Bark ◽  
Drug Resistant ◽  
Albizia Lebbeck ◽  
Antimicrobial Drugs ◽  
Methicillin Resistant ◽  
Resistant Strains ◽  
Drug Resistant Strains

The emergence of multi-drug resistant strains and limitations of present antimicrobial drugs have led to continuous search for natural products as curative agents for Anti-methicillin resistantinfections. The aim of this study was to evaluate antibacterial activity of an ethanolic extract from Albizia lebbeckstem bark against Anti-methicillin resistant. Methods and Results : The methods of dissemination swab on muller-hinton agar and double dilution were used to evaluate the antibacterial activity of 70 % ethanolic extract of stem bark of Albizia lebbeck.All multi-resistant strains of Staphylococcus aureus and the reference strain (ATCC 25923) were sensitive to 70 % ethanolic extract of the stem bark of Albizia lebbeck. The MBCvary from 0,49 mg/mL to 2mg/mL. Also, the phytochemical screening of this extract revealed the presence of  Polyphenols, Gallic tannins, Catechin tanninsand Flavonoids. These findings confirm that an 70 % ethanolic extract from Albizia lebbeck stem bark inhibited growth of Anti-methicillin resistant at low concentration and could be utilised as an alternative Anti-methicillin resistantagent.

scholarly journals Effect of Storage Period on Silver Nanoparticles Biosynthesized By Pseudomonas Aeroginosa

2019 ◽  
Vol 9 (04) ◽  
pp. 678-681
Author(s):  
Ashraf S Hassan ◽  
Khawlah J Khalaf ◽  
Hamzia A Ajah
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Candida Albicans ◽  
Storage Period ◽  
Before And After ◽  
Pathogenic Microbes

The present study demonstrates the effect of storage period on silver nanoparticles (AgNPs), which synthesized by Pseudomonas aeruginosa and their antibacterial activity. The result shows that the size of (AgNPs) which synthesis by Pseudomonas aeruginosa was 93.55nm after 4-72hour, and when storage about 2 years, we found that the size of AgNPs was stable and reduced to 69.0nm. Antibacterial activity against pathogenic microbes: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Serratia sp,Streptococcus sp , Klebsiella sp, Candida albicans was performed before and after storage and found that AgNPs have activity against this microbes.

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