Conversion of cannabidiol to Δ9-tetrahydrocannabinol and related cannabinoids in artificial gastric juice, and their pharmacological effects in mice

2007 ◽  
Vol 25 (1) ◽  
pp. 16-21 ◽  
Author(s):  
Kazuhito Watanabe ◽  
Yuka Itokawa ◽  
Satoshi Yamaori ◽  
Tatsuya Funahashi ◽  
Toshiyuki Kimura ◽  
...  
Keyword(s):  
Gastric Juice ◽  
Pharmacological Effects ◽  
Artificial Gastric Juice

scholarly journals In vitro assessment of the probiotic potential of lactobacilli isolated from Minas artisanal cheese produced in the Araxá region, Minas Gerais state, Brazil

2019 ◽  
Vol 71 (2) ◽  
pp. 647-657 ◽  
Author(s):  
J.G. Silva ◽  
R.D. Castro ◽  
F.M. Sant’Anna ◽  
R.M. Barquete ◽  
L.G. Oliveira ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Gastric Juice ◽  
Minas Gerais ◽  
Starter Cultures ◽  
Probiotic Properties ◽  
Probiotic Potential ◽  
Three Samples ◽  
Production Of Hydrogen ◽  
Artificial Gastric Juice

ABSTRACT Minas artisanal cheese is made from endogenous starter cultures, including lactic acid bacteria (LAB). Some LAB may possess probiotic potential. Thus, this study aimed to evaluate the in vitro probiotic properties of lactobacilli isolated from Minas artisanal cheeses produced in Minas Gerais. Ten samples of lactobacilli, formerly isolated from those cheeses, were submitted to the following assays: antimicrobial susceptibility, tolerance to artificial gastric juice and biliary salts, production of hydrogen peroxide and antagonism against pathogenic and non-pathogenic micro-organisms. Only L. plantarum (C0) was sensitive to all tested antimicrobials, while the other LAB samples were resistant to at least one drug. Six samples were tolerant to artificial gastric juice, and L. brevis (A6) even grew in that medium. Three samples were tolerant to biliary salts. Only L. brevis (E35) produced hydrogen peroxide. Difference (P< 0.05) was observed among the means of inhibition haloes of lactobacilli against Enterococcus faecalis ATCC 19433 and Lactobacillus plantarum C24 in spot-on-the-lawn assay. All samples of lactobacilli inhibited Escherichia coli ATCC 25922, Salmonella enterica var. Typhimurium ATCC 14028 in co-culture antagonism test (P< 0.0001). Most lactobacilli samples showed in vitro probiotic potential. From the tested samples, L. brevis (A6) presented the best results considering all in vitro probiotic tests.

New application of hierarchical zeolite in life science: Fast trapping nitrosamines in artificial gastric juice by alkaline-tailored HZSM-5

2007 ◽  
Vol 61 (14-15) ◽  
pp. 3154-3158 ◽  
Author(s):  
Xin Dong ◽  
Chun Fang Zhou ◽  
Ming Bo Yue ◽  
Cai Zhe Zhang ◽  
Wei Huang ◽  
...  
Keyword(s):  
Gastric Juice ◽  
Life Science ◽  
Hierarchical Zeolite ◽  
Artificial Gastric Juice

scholarly journals Elucidation of Degradation Behavior of Tricyclic Antidepressant Amoxapine in Artificial Gastric Juice

2020 ◽  
Vol 68 (9) ◽  
pp. 848-854
Author(s):  
Koichi Saito ◽  
Nami Hagiwara ◽  
Miho Sakamoto ◽  
Daigo Wakana ◽  
Rie Ito ◽  
...  
Keyword(s):  
Gastric Juice ◽  
Tricyclic Antidepressant ◽  
Degradation Behavior ◽  
Artificial Gastric Juice

The metabolism of Lonicera japonica by artificial gastric juice

Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
L Lin ◽  
Z Wang ◽  
C Li ◽  
W Wang
Keyword(s):  
Gastric Juice ◽  
Lonicera Japonica ◽  
Artificial Gastric Juice

Hydrolysis of 2-Chloroethyl Palmitate and 2-Chloroethyl Linoleate by Mammalian Enzymes

1981 ◽  
Vol 44 (2) ◽  
pp. 112-114 ◽  
Author(s):  
JOHN J. SULLIVAN ◽  
JOHN J. MAJNARICH
Keyword(s):  
Liquid Chromatography ◽  
Gastric Juice ◽  
Pancreatic Juice ◽  
Hydrolytic Activity ◽  
Gas Liquid Chromatography ◽  
Pig Liver ◽  
Hydrolysis Constants ◽  
Artificial Gastric Juice ◽  
Liver Homogenates ◽  
Hydrolysis Of

Hydrolysis of 2-chloroethyl palmitate and 2-chloroethyl linoleate was studied in artificial gastric juice, artificial pancreatic juice, pig liver homogenates and pig intestine homogenates. Hydrolytic activity was followed by gas-liquid chromatography. Substantial hydrolysis was observed in all preparations except the artificial gastric juice. Hydrolysis constants ranged from &lt;0.001 min−1 in the gastric juice to 0.064 min−1 for the linoleate ester in the pancreatic juice.

Survival to artificial gastric juice of Lactobacillus delbrueckii microencapsulated using different calcium dosage

2018 ◽  
Vol 11 (27) ◽  
pp. 1313-1321
Author(s):  
Rafael Gonzalez-Cuello ◽  
Lena Beatriz Moron-Alcazar ◽  
Jaime Perez-Mendoza
Keyword(s):  
Gastric Juice ◽  
Lactobacillus Delbrueckii ◽  
Artificial Gastric Juice

The Excystment of Trichinella larvae in Artificial Gastric Juice

1937 ◽  
Vol 15 (4) ◽  
pp. 177-182
Author(s):  
Vernon D. van Someren
Keyword(s):  
Gastric Juice ◽  
Stomach Contents ◽  
Secretory Activity ◽  
Experimental Animals ◽  
Experimental Host ◽  
Artificial Gastric Juice ◽  
Short Time

By feeding infected flesh to experimental animals, and examining the stomach contents of the latter at varying periods after feeding, various workers have shown that Trichinella larvae are released from their cysts within one or two hours after reaching the stomach of the experimental host. (Bugge, 1934, Heller, 1933, 1934, Kreis, 1937.) The actual release of the larvae from the cysts has not been followed, though Kreis (1937) on the basis of the appearance of stained cysts recovered a short time after ingestion, suggests that the larvae are released not only by the action of the gastric juice of the host, but also as a result of secretory activity by the larvae themselves within the cysts.

scholarly journals Role and mechanism of Glut-1 and H+/K+-ATPase expression in pepsin-induced development of vocal cord leukoplakia

2021 ◽  
Author(s):  
Yin-Jie Ao ◽  
Ting-Ting Wu ◽  
Zai-Zai Cao ◽  
Shui-Hong Zhou ◽  
Yang-Yang Bao ◽  
...  
Keyword(s):  
Gastric Juice ◽  
Vocal Cord ◽  
Laryngeal Carcinoma ◽  
G1 Phase ◽  
Dependent Manner ◽  
Glut 1 ◽  
Laryngeal Mucosa ◽  
M Phase ◽  
Artificial Gastric Juice

Abstract Purpose We investigated the role of Glut-1 and H+/K+-ATPase expression in pepsin-induced development of human vocal cord leukoplakia cells (HVCLCs). Next, we analyzed the relationship between Glut-1 and H+/K+-ATPase expression with the clinicopathological features of laryngeal carcinoma. Methods Glut-1 and H+/K+-ATPase expression levels in HVCLCs were determined after treatment with artificial gastric juice containing pepsin and laryngeal carcinoma tissues. Results Exposure to pepsin-containing artificial gastric juice significantly enhanced the migration and proliferation of VSCLCs in a time-dependent manner. The apoptotic rate of VSCLCs decreased over time after exposure to pepsin and reached a nadir on day 7 (p < 0.01). With increasing duration of exposure to pepsin, the proportion of VSCLCs in G0/G1 phase decreased and the proportions in the S and G2/M phases significantly increased (p < 0.05). After treatment with pepsin-containing artificial gastric juice, RT-PCR and Western blotting showed that the expression of Glut-1 and H+/K+-ATPase α, β significantly increased in HVCLCs compared to in the absence of pepsin (p < 0.05). The expression of Glut-1 and H+/K+-ATPase α, β gradually increased from vocal cord leukoplakia (VLC) to laryngeal carcinoma (p < 0.05). Lentivirus-mediated inhibition of Glut-1 expression in VCL significantly inhibited the cells’ migration and proliferation (p < 0.05) but enhanced their apoptosis (p < 0.05). Also, inhibition of Glut-1 expression resulted in an increased proportion of cells in G0/G1 phase and a significantly decreased proportion in G2/M phase (p < 0.05). Conclusions Elevated Glut-1 expression may promote the development of VCL by upregulating laryngeal H+/K+-ATPase expression to reactivate absorbed pepsin, thus damaging the laryngeal mucosa.

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