Sertoli-stromal cell tumor of the right ovary: radiological-pathological correlation

2006 ◽  
Vol 24 (8) ◽  
pp. 592-594
Author(s):  
Toshiko Yamano ◽  
Kumiko Ando ◽  
Reiichi Ishikura ◽  
Norio Nakao ◽  
Toshitada Ogasawara
Keyword(s):  
Stromal Cell ◽  
Cell Tumor ◽  
Pathological Correlation ◽  
The Right

scholarly journals Desmoplastic Small Round Cell Tumor of the Submandibular Gland: A Case Report and Literature Review

ORL ◽  
2021 ◽  
pp. 1-6
Author(s):  
Qingjiao Li ◽  
Xiaolu Yuan
Keyword(s):  
Submandibular Gland ◽  
Young Patients ◽  
Neck Region ◽  
Cell Tumor ◽  
Pelvic Cavity ◽  
Round Cell ◽  
Round Cell Tumor ◽  
Small Round Cell Tumor ◽  
Small Round Cell ◽  
The Right

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressively malignant tumor mostly occurring in the abdominal and pelvic cavity of young patients. However, few cases had been reported concerning DSRCT occurring in the head and neck region. We presented a rare case of DSRCT of the right submandibular in a 25-year-old man. MRI revealed a 3 × 2-cm solid nodule located in the right submandibular, and physical examination showed no other occupying lesion elsewhere. Histologically, the tumor was composed of various-sized small round cell nests, embedded in an abundant desmoplastic stroma. Immunohistochemically, the tumor cells were typically positive for epithelial (CK and EMA), mesenchymal (vimentin and desmin), and neuroendocrine (CD56, NSE, Syn, and CgA) markers, but negative for WT1. Fluorescence in situ hybridization revealed the presence of a break apart involving the <i>Ewing sarcoma</i> (<i>EWS</i>) gene. The patient received chemotherapy and radiotherapy and relapsed after 19 months of follow-up. DSRCT of the submandibular gland is rare, and the diagnosis of this tumor in an uncommon location relies on the histomorphology, immunophenotype, and <i>EWS</i> gene translocation detection. Differential diagnosis including primary salivary gland tumors and the other small round cell tumors needs to be excluded.

scholarly journals The local spread of pheochromocytoma after adrenalectomy with a rupture of the tumor capsule at the time of the surgery

Open Medicine ◽  
2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Ryszard Pogorzelski ◽  
Sadegh Toutounchi ◽  
Patryk Fiszer ◽  
Ewa Krajewska ◽  
Izabela Łoń ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
Chromaffin Cell ◽  
Cell Tumor ◽  
Cell Seeding ◽  
Case Presentation ◽  
Tumor Capsule ◽  
Exact Localization ◽  
Local Spread ◽  
The Right ◽  
Multiple Recurrences

AbstractIntroduction: We present a case of a 29-year-old patient treated due to fully symptomatic pheochromocytoma of the right adrenal gland. Case presentation: Patient was operated on and an open right-sided adrenalectomy was performed. At the time of the surgery, a rupture of the tumor capsule occurred. Five years post-operatively, a recurrence of the symptoms of chromaffin-cell tumor was noted. After the exact localization of the multiple recurrences, the patient was reoperated on. Conclusion: The case of pheochromocytoma is presented due to the possibility of chromaffin-cell seeding into the peritoneum, with no signs of distal metastases so far.

scholarly journals Improved hematopoiesis in anemic Sl/Sld mice by splenectomy and therapeutic transplantation of a hematopoietic microenvironment

Blood ◽  
1989 ◽  
Vol 74 (3) ◽  
pp. 1144-1151
Author(s):  
P Anklesaria ◽  
TJ FitzGerald ◽  
K Kase ◽  
A Ohara ◽  
JS Greenberger
Keyword(s):  
Bone Marrow ◽  
Cell Line ◽  
Hind Limb ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Volume Distribution ◽  
Distribution Analysis ◽  
Marrow Stromal Cell ◽  
Stromal Cell Line ◽  
The Right

The ability of a clonal hematopoiesis-supportive bone-marrow stromal cell line GBlneor to engraft and alter the microenvironment-induced anemia of Sl/Sld mice was studied. Prior to stromal cell transplantation, Sl/Sld mice received 1 Gy total body irradiation (TBI) and 13 Gy to the right hind limb. Two months after intravenous (IV) injection of 5 x 10(5) GBlneor cells, 54.4% +/- 17.0% donor origin (G418r) colony-forming cells were recovered from the right hind limb of Sl/Sld mice. Long-term bone marrow cultures (LTBMCs) established from GBlneor-transplanted mice produced 189.5 CFU-GEMM-forming progenitors/flask over 10 weeks compared with 52.7 +/- 6.2 CFU-GEMM forming progenitors/flask from irradiated nontransplanted Sl/Sld mice. A partial correction of macrocytic anemia was detected 2 months after GBlneor transplantation in splenectomized, irradiated Sl/Sld mice (HgB 7.2 +/- 0.4 g/dL; MCV 68.3 +/- 7.0 fL) compared to splenectomized, irradiated, nontransplanted Sl/Sld mice (HgB 5.5 +/- 1.1 g/dL; MCV 76 +/- 8.5 fL) or control Sl/Sld mice (HgB 5.4 +/- 0.5 g/dL; MCV 82.4 +/- 1.3 fL). Mean RBC volume distribution analysis showed a 2.5-fold increase in percentage of peripheral blood RBCs with MCV less than or equal to 45 fL and confirmed reduction of the MCV in splenectomized- GBlneor-transplanted mice compared to control Sl/Sld mice. A hematopoiesis-suppressive clonal stromal cell line derived from LTBMCs of Sl/Sld mice (Sldneor) engrafted as effectively (43.5% +/- 1.2% G418r CFU-F/limb) as did GBlneor cells (38.3% +/- 0.16% G418r CFU-F/limb) to the irradiated right hind limbs of C57Bl/6 mice. LTBMCs established after 2 or 6 months from Sldneor-transplanted mice showed decreased hematopoiesis (182 +/- 12 [2 months] and 3494.3 +/- 408.1 [6 months] CFU-GEMM forming progenitors/flask over 10 weeks) compared to those established from GBlneor-transplanted mice (5980 +/- 530 [2 months] and 7728 +/- 607, [6 months] CFU-GEMM progenitors forming/flask). Thus, transplantation of clonal bone-marrow stromal cell lines in vivo can stably transfer their physiologic properties to normal or mutant mice.

scholarly journals Matrix Metalloproteinase Activity in the Stromal Cell of Giant Cell Tumor of Bone

2009 ◽  
Vol 1 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Alexander Rabinovich ◽  
Isabella W.Y. Mak ◽  
Robert W. Cowan ◽  
Robert E. Turcotte ◽  
Nigel Colterjohn ◽  
...  
Keyword(s):  
Matrix Metalloproteinase ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Stromal Cell ◽  
Cell Tumor ◽  
Metalloproteinase Activity

scholarly journals Giant Cell Tumor of Bone: A rare uncommon manifestation implicated in a new mosaic of desorders?

2021 ◽  
Author(s):  
Eliandro de Souza Freitas ◽  
Francisco Amadis Batista Ferreira ◽  
Brendo Vinícius Rodrigues Louredo ◽  
Milena Gomes Melo Leite ◽  
José da Cruz Luna Neto ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Rare Case ◽  
Benign Neoplasm ◽  
Cell Tumor ◽  
Long Bones ◽  
The Right

Giant Cell Tumor of Bone is an uncommon aggressive benign neoplasm that frequently affecting the epiphysis of long bones especially around the knee. This is a singular rare case of GCTB in the right maxillary sinus implicated in a process coincidentally or casually with another type of lesion primarily developed.

Extraventricular subependymal giant cell tumor in a child with tuberous sclerosis complex

2009 ◽  
Vol 4 (1) ◽  
pp. 85-90 ◽  
Author(s):  
Robert J. Bollo ◽  
Jonathan L. Berliner ◽  
Ingeborg Fischer ◽  
Daniel K. Miles ◽  
Elizabeth A. Thiele ◽  
...  
Keyword(s):  
Tuberous Sclerosis ◽  
Giant Cell ◽  
Tuberous Sclerosis Complex ◽  
Rapid Growth ◽  
Neonatal Period ◽  
Cell Tumor ◽  
Giant Cell Tumors ◽  
Neurological Morbidity ◽  
Cortical Tubers ◽  
The Right

Subependymal giant cell tumors (SGCTs) are observed in 5–20% of patients with tuberous sclerosis complex (TSC) but account for ~ 25% of neurological morbidity. The authors report the case of a 7-year-old girl with TSC and multiple cortical tubers who presented with worsening seizures in the context of the rapid growth of a cystic, calcified, extraventricular SGCT in the right frontal lobe, initially thought to represent a cortical tuber. The tumor and surrounding tubers were excised, and clinical seizures resolved. This is the first report of an extraventricular SGCT in a child with TSC outside the neonatal period.

Interstitial cell tumor in the right testis of a Southern flying squirrel (Glaucomys volans)

2021 ◽  
Author(s):  
Nguyen Vu Son ◽  
James Kenn Chambers ◽  
Makoto Nakata ◽  
Yagutsu Miwa ◽  
Hiroyuki Nakayama ◽  
...  
Keyword(s):  
Interstitial Cell ◽  
Cell Tumor ◽  
Glaucomys Volans ◽  
Flying Squirrel ◽  
The Right ◽  
Southern Flying Squirrel

scholarly journals Brown Tumor of the Facial Bones: Case Report and Literature Review

2005 ◽  
Vol 84 (7) ◽  
pp. 432-434 ◽  
Author(s):  
Marcus M. Lessa ◽  
Flavio A. Sakae ◽  
Robinson K. Tsuji ◽  
Bernardo C. Araújo Filho ◽  
Richard L. Voegels ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Surgical Resection ◽  
Tumor Regression ◽  
Cell Tumor ◽  
Nasal Fossa ◽  
Laboratory Evaluation ◽  
Direct Result ◽  
Brown Tumor ◽  
The Right

Brown tumor, an uncommon focal giant-cell lesion, arises as a direct result of the effect of parathyroid hormone on bone tissue in patients with hyperparathyroidism. The initial treatment involves the correction of hyperparathyroidism, which usually leads to tumor regression. We report a case of brown tumor of the right nasal fossa in a 71-year-old woman. The tumor had caused nasal obstruction and epistaxis. Laboratory evaluation revealed that the patient had primary hyperparathyroidism. Anatomicopathologic investigation revealed the presence of a giant-cell tumor. We performed a partial parathyroidectomy, but the tumor in the right nasal fossa failed to regress. One year later, we performed surgical resection of the lesion. The patient recovered uneventfully, and she remained asymptomatic and recurrence-free at the 1-year follow-up. Facial lesions with histologic features of a giant-cell tumor should be evaluated from a systemic standpoint. Hyperparathyroidism should always be investigated by laboratory tests because most affected patients are asymptomatic. Surgical resection of a brown tumor should be considered if the mass does not regress after correction of the inciting hyperparathyroidism or if the patient is highly symptomatic.

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