scholarly journals DNA repair gene polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis

2011 ◽  
Vol 23 (2) ◽  
pp. 79-91 ◽  
Author(s):  
Chao-rong Mei ◽  
Meng Luo ◽  
Hong-mei Li ◽  
Wen-jun Deng ◽  
Qing-hua Zhou
Keyword(s):  
Lung Cancer ◽  
Gene Polymorphisms ◽  
Lung Cancer Risk ◽  
Excision Repair ◽  
Meta Analysis ◽  
Repair Pathway ◽  
Repair Gene ◽  
Dna Repair Gene ◽  
Nucleotide Excision ◽  
Nucleotide Excision Repair Pathway

DNA repair gene XPD polymorphism and lung cancer risk: a meta-analysis

Lung Cancer ◽  
2004 ◽  
Vol 46 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Z. Hu ◽  
Q. Wei ◽  
X. Wang ◽  
H. Shen
Keyword(s):  
Lung Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Meta Analysis ◽  
Repair Gene ◽  
Dna Repair Gene

scholarly journals Nucleotide excision repair pathway gene polymorphisms are linked to breast cancer risk in a Chinese population

Oncotarget ◽  
2016 ◽  
Vol 7 (51) ◽  
pp. 84872-84882 ◽  
Author(s):  
Bang-shun He ◽  
Tao Xu ◽  
Yu-qin Pan ◽  
Han-jin Wang ◽  
William C. Cho ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Gene Polymorphisms ◽  
Chinese Population ◽  
Excision Repair ◽  
Repair Pathway ◽  
Pathway Gene ◽  
Nucleotide Excision ◽  
Nucleotide Excision Repair Pathway

scholarly journals The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair.

1995 ◽  
Vol 15 (12) ◽  
pp. 7067-7080 ◽  
Author(s):  
A R Lehmann ◽  
M Walicka ◽  
D J Griffiths ◽  
J M Murray ◽  
F Z Watts ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Dna Repair ◽  
Schizosaccharomyces Pombe ◽  
Gene Deletion ◽  
Excision Repair ◽  
Repair Pathway ◽  
Repair Gene ◽  
Dna Repair Gene ◽  
Nucleotide Excision ◽  
Biochemical Analyses

The rad18 mutant of Schizosaccharomyces pombe is very sensitive to killing by both UV and gamma radiation. We have cloned and sequenced the rad18 gene and isolated and sequenced its homolog from Saccharomyces cerevisiae, designated RHC18. The predicted Rad18 protein has all the structural properties characteristic of the SMC family of proteins, suggesting a motor function--the first implicated in DNA repair. Gene deletion shows that both rad18 and RHC18 are essential for proliferation. Genetic and biochemical analyses suggest that the product of the rad18 gene acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair. This second repair pathway involves the products of the rhp51 gene (the homolog of the RAD51 gene of S. cerevisiae) and the rad2 gene.

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