Predictive value of brain MRI at term-equivalent age in extremely preterm children on neurodevelopmental outcome at school-age

2021 ◽  
Author(s):  
Aurélie Garbi ◽  
Gaelle Sorin ◽  
Stéphanie Coze ◽  
Noémie Resseguier ◽  
Véronique Brévaut-Malaty ◽  
...  
Keyword(s):  
Predictive Value ◽  
Brain Mri ◽  
Neurodevelopmental Outcome ◽  
School Age ◽  
Preterm Children ◽  
Equivalent Age ◽  
Extremely Preterm

scholarly journals Early Screening of Visual Processing Dysfunctions in Children Born Very or Extremely Preterm

2021 ◽  
Vol 15 ◽  
Author(s):  
Marlou J. G. Kooiker ◽  
Maud M. van Gils ◽  
Ymie J. van der Zee ◽  
Renate M. C. Swarte ◽  
Liesbeth S. Smit ◽  
...  
Keyword(s):  
At Risk ◽  
Brain Damage ◽  
Visual Function ◽  
Visual Processing ◽  
Neurodevelopmental Outcome ◽  
Risk Groups ◽  
Diagnostic Methods ◽  
School Age ◽  
Neurological Signs ◽  
Extremely Preterm

Introduction: Children with early brain damage or dysfunction are at risk of developing cerebral visual impairment (CVI), including visual processing dysfunctions (VPD), which currently remain largely undetected until school age. Our aim was to systematically screen for possible VPD in children born very or extremely preterm from 1 to 2 years corrected age (CA) and to evaluate the effectiveness of early referral.Method: We included N = 48 children born < 30 weeks from 1 year CA. They underwent a two-step VPD screening based on (1) neurological signs indicative of visual brain damage evaluated by neonatologists and/or pediatric neurologist and (2) a functional assessment of visual orienting functions (VOF) with an eye tracking-based test. If at least one of these assessments was abnormal for their age, the children were classified as a risk of VPD and referred to undergo conventional visual diagnostics: ophthalmic exam and visual function assessment (VFA). At 2 years CA, VOF screening was repeated and neurodevelopment was assessed.Results: 18 children (38%) were classified as at risk of VPD at 1 year CA. 7 children had abnormal neurological signs, 5 children had abnormal VOF, and 6 children had both. Subsequent ophthalmic exams (N = 14) showed severe hypermetropia in 21% and strabismus in 14%. VFA (N = 10) showed abnormal visual function and behavior in only 1 child. At 2 years CA, the total group showed an increase in abnormal VOF. Whereas the children at risk showed some normalization, the group without VPD risk at 1 year CA showed deterioration of VOF. Neurodevelopmental outcome did not clearly differ between risk groups.Conclusion: Our findings show a substantial risk of VPD during visual screening (in 38%) at 1 year CA, but relatively few deficits on subsequent conventional ophthalmic exams and VFA. The data suggest that most conventional visual diagnostic methods at this young age are not related to the established VPD risks. VOF assessment should be used complimentary to these methods. The fact that at 2 years CA the number of children with a VPD risk based on abnormal VOF increased argues for more extensive and continuous screening in risk groups, at least until school age.

scholarly journals Neurodevelopmental outcome at early school age in a Swiss national cohort of very preterm children

2019 ◽  
Author(s):  
Marie P. Pittet-Metrailler ◽  
Ines Mrner-Lavanchy ◽  
Mark Adams ◽  
Myriam Bickle Graz ◽  
Riccardo E. Pfister ◽  
...  
Keyword(s):  
Neurodevelopmental Outcome ◽  
School Age ◽  
Preterm Children ◽  
Very Preterm ◽  
Early School ◽  
National Cohort ◽  
Early School Age

scholarly journals Association of Antenatal Corticosteroids and Magnesium Sulfate Therapy With Neurodevelopmental Outcome in Extremely Preterm Children

2020 ◽  
Vol 135 (6) ◽  
pp. 1377-1386 ◽  
Author(s):  
Samuel J. Gentle ◽  
Waldemar A. Carlo ◽  
Sylvia Tan ◽  
Marissa Gargano ◽  
Namasivayam Ambalavanan ◽  
...  
Keyword(s):  
Magnesium Sulfate ◽  
Neurodevelopmental Outcome ◽  
Antenatal Corticosteroids ◽  
Preterm Children ◽  
Extremely Preterm

Brain Volumes at Term-Equivalent Age in Preterm Infants: Imaging Biomarkers for Neurodevelopmental Outcome through Early School Age

2016 ◽  
Vol 172 ◽  
pp. 88-95 ◽  
Author(s):  
Kristin Keunen ◽  
Ivana Išgum ◽  
Britt J.M. van Kooij ◽  
Petronella Anbeek ◽  
Ingrid C. van Haastert ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Neurodevelopmental Outcome ◽  
Imaging Biomarkers ◽  
School Age ◽  
Brain Volumes ◽  
Equivalent Age ◽  
Early School ◽  
Early School Age

scholarly journals Predictive value of neonatal brain MRI on the neurodevelopmental outcome of preterm infants by 5 years of age

2013 ◽  
Vol 102 (5) ◽  
pp. 492-497 ◽  
Author(s):  
Sirkku Setänen ◽  
Leena Haataja ◽  
Riitta Parkkola ◽  
Annika Lind ◽  
Liisa Lehtonen ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Predictive Value ◽  
Brain Mri ◽  
Neurodevelopmental Outcome ◽  
Neonatal Brain

Intubation-Related Dysphonia Following Extreme Preterm Birth: Case Studies in Behavioural Voice Intervention

2014 ◽  
Vol 24 (3) ◽  
pp. 124-129 ◽  
Author(s):  
Victoria Reynolds ◽  
Suzanne Meldrum ◽  
Karen Simmer ◽  
Shyan Vijayasekaran ◽  
Noel French
Keyword(s):  
Preterm Birth ◽  
Case Studies ◽  
Neonatal Period ◽  
Behavioral Outcomes ◽  
Voice Therapy ◽  
School Age ◽  
Review Of The Literature ◽  
Preterm Children ◽  
Voice Production ◽  
Extremely Preterm

Many more children than ever before survive and thrive following preterm birth (Saigal & Doyle, 2008). To date, research has focussed on medical, developmental, neurological, and behavioral outcomes. As the number of surviving children increases and survivors reach school age and beyond, it has become apparent that many children experience difficulties with voice production (French et al., 2013). Following preterm birth, endotracheal intubation may be necessary to deliver surfactant or relieve respiratory distress during the neonatal period (Ho, Subramaniam, Henderson-Smart, & Davis, 2002). Intubation injury to the larynx and resultant dysphonia are well described in the literature (Bray, Cavalli, Eze, Mills, & Hartley, 2010). This article presents a brief review of the literature relevant to intubation-related injury following preterm birth and 2 case studies of voice outcomes following a trial of behavioral voice therapy in extremely preterm children who were intubated.

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