Hypothesis, modern researches and clinical applications of cutaneous regions in traditional Chinese medicine

2014 ◽  
Vol 12 (2) ◽  
pp. 125-132 ◽  
Author(s):  
Lei Fan ◽  
Lei-miao Yin
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Clinical Applications

The Principle of Symmetry in Acupuncture and its Clinical Applications

2013 ◽  
Vol 41 (06) ◽  
pp. 1223-1231 ◽  
Author(s):  
Tsun-Nin Lee
Keyword(s):  
Clinical Practice ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Scientific Literature ◽  
Clinical Applications ◽  
The Body ◽  
Therapeutic Effects ◽  
Thalamic Neuron ◽  
Axis Of Symmetry ◽  
Symmetrical Points

The clinical practice of acupuncture and study of the traditional Chinese medicine literature has led to the observation that if the diaphragm is used as an axis of symmetry, there are many symmetrical points on the upper and lower halves of the body. The symmetrical points share several common properties, including physiological functions, mechanisms of pathogenesis and therapeutic effects. Employing these corresponding points on the upper and lower parts of the body simultaneously can frequently enhance the therapeutic outcome rather substantially. This phenomenon may be called the Principle of Symmetry. Traditional and modern scientific literature already provides evidence that verifies the reliability of this principle. Furthermore, this principle may be viewed as the derivative of the Thalamic Neuron Theory.

scholarly journals Clinical Applications of Omics Technologies on ZHENG Differentiation Research in Traditional Chinese Medicine

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Ya-Nan Song ◽  
Gui-Biao Zhang ◽  
Yong-Yu Zhang ◽  
Shi-Bing Su
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Clinical Applications ◽  
Diagnostic Methods ◽  
Biological Mechanisms ◽  
Omics Technologies ◽  
Functional Activities ◽  
Wide Perspective ◽  
Tcm Theory ◽  
Zheng Differentiation

Traditional Chinese medicine (TCM) ZHENG is the basic concept of TCM theory. The effectiveness of TCM treatment depends on the accuracy of ZHENG differentiation. ZHENG differentiation, using the “four diagnostic methods,” has the drawbacks of subjectivity and variability. Following development of omics technologies, which study the functional activities of human body from a system-wide perspective, it has been more and more applied in study of objectivity differentiating TCM ZHENG and understanding its biological mechanisms. This paper reviewed the literatures of clinical TCM ZHENG differentiation researches, underlying omics technologies, and indicated the increased trends of related articles with four kinds of omics technologies, including genomics, transcriptomics, proteomics and metabolomics, and the correlations between ZHENG differentiation and findings in omics studies. Moreover, the paper summarized the typical omics application in common studied diseases and TCM ZHENGs and discussed the main problems and countermeasure of ZHENG differentiation researches. The work here may provide a reference for further research of TCM ZHENG differentiation using omics technologies.

scholarly journals Research Advances in Pharmacology, Safety, and Clinical Applications of Yunnan Baiyao, a Traditional Chinese Medicine Formula

2021 ◽  
Vol 12 ◽  
Author(s):  
Qi Yao ◽  
Bo-tao Chang ◽  
Rong Chen ◽  
Yi-jing Wei ◽  
Qiu-ju Gong ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Blood Stasis ◽  
Early Embryo ◽  
Clinical Applications ◽  
Number Of Patients ◽  
Toxicological Studies ◽  
Yunnan Baiyao

Ethnopharmacology relevance: Yunnan Baiyao (YNBY), a traditional Chinese medicine formulae, has some significant properties including activating blood circulation to dissipate blood stasis (Huo-Xue-Hua-Yu), eliminating swelling and alleviating pain (Xiao-Zhong-Zhi-Tong), and eliminating necrotic tissues and promoting granulation (Qu-Fu-Sheng-Ji).Aim of this study: This paper intends to provide a comprehensive and critical analysis of studies on YNBY, proposing new possible therapeutic directions of this formula.Materials and methods: Relevant data on YNBY were retrieved from available databases and a hand-search by searching the keywords such as “Yunnan Baiyao,” “pharmacology,” “toxicity,” and “clinical applications.”Results: Traditionally, YNBY has been used to cure hemorrhage, bruises, swelling, and pain caused by injuries in the Chinese folk. Modern pharmacological studies show that YNBY possesses pharmacological activities including hemostasis, invigorating the circulation of blood, wound healing, anti-inflammation, analgesia, antibiosis, infection prevention, and other effects. Toxicological studies demonstrate that YNBY has a certain toxicology, which is mainly caused by Aconitum alkaloids from Cao-wu (CW, Aconiti Kusnezoffii Radix). The developmental non-toxic reaction dose (NOAEL) of YNBY for embryos and fetuses is 0.5 g/kg in rats. In addition, the NOAEL for fertility and early embryo development toxicity is 4.0 g/kg in rats. Clinical trials have confirmed the safety of YNBY in a large number of patients, and adverse drug reactions (ADRs) such as abdominal pain, diarrhea, allergy, and others in very few people. YNBY is routinely used in clinic to cure bleeding, pain, swelling, upper digestive tract ulcer, postoperative wound, arthritis, mouth ulcers, ulcerative colitis, etc.Conclusions: Hemostasis is a conspicuous effect of YNBY. Except for this effect, analgesia and anti-infection may be new research directions of this formula. In addition, the in vitro and in vivo pharmacology and mechanisms of action of YNBY are encouraged as well as the pharmacokinetics of this formulae. Furthermore, the material basis of the pharmacological effects of YNBY also needs clear identification.

scholarly journals Artemether, Artesunate, Arteannuin B, Echinatin, Licochalcone B and Andrographolide Effectively Inhibit SARS-CoV-2 and Related Viruses In Vitro

2021 ◽  
Vol 11 ◽  
Author(s):  
Yunjia Hu ◽  
Meiqin Liu ◽  
Hongbo Qin ◽  
Haofeng Lin ◽  
Xiaoping An ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Early Stage ◽  
Clinical Applications ◽  
The Novel ◽  
Compound Library ◽  
Global Pandemic ◽  
Novel Coronavirus ◽  
And Control

Since the first reported case caused by the novel coronavirus SARS-CoV-2 infection in Wuhan, COVID-19 has caused serious deaths and an ongoing global pandemic, and it is still raging in more than 200 countries and regions around the world and many new variants have appeared in the process of continuous transmission. In the early stage of the epidemic prevention and control and clinical treatment, traditional Chinese medicine played a huge role in China. Here, we screened out six monomer compounds, including artemether, artesunate, arteannuin B, echinatin, licochalcone B and andrographolide, with excellent anti-SARS-CoV-2 and anti-GX_P2V activity from Anti-COVID-19 Traditional Chinese Medicine Compound Library containing 389 monomer compounds extracted from traditional Chinese medicine prescriptions “three formulas and three drugs”. Our discovery preliminary proved the stage of action of those compounds against SARS-CoV-2 and provided inspiration for further research and clinical applications.

Recent Development of Oridonin Derivatives with Diverse Pharmacological Activities

2018 ◽  
Vol 19 (2) ◽  
pp. 114-124 ◽  
Author(s):  
Weiyan Cheng ◽  
Chuanhui Huang ◽  
Weifeng Ma ◽  
Xin Tian ◽  
Xiaojian Zhang
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Biological Activities ◽  
Biological Properties ◽  
Clinical Applications ◽  
Structure Modification ◽  
Pharmacological Activities ◽  
The Poor ◽  
Structure Activity ◽  
Anti Inflammation

Oridonin is one of the major components isolated from Isodon rubescens, a traditional Chinese medicine, and it has been confirmed to exhibit many kinds of biological activities including anticancer, anti-inflammation, antibacterial and so on. However, the poor pharmaceutical property limits the clinical applications of oridonin. So many strategies have been explored in the purpose of improving the potencies of oridonin, and structure modification is one thus way. This review outlines the landscape of the recent development of oridonin derivatives with diverse pharmacological activities, mainly focusing on the biological properties, structure-activity relationships, and mechanism of actions.

Traditional Chinese Medicine and Constitutional Medicine in China, Japan and Korea: A Comparative Study

2017 ◽  
Vol 45 (01) ◽  
pp. 1-12 ◽  
Author(s):  
Wenjun Yu ◽  
Mingyue Ma ◽  
Xuemei Chen ◽  
Jiayu Min ◽  
Lingru Li ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Clinical Applications ◽  
Syndrome Differentiation ◽  
Constitutional Theory ◽  
Medical Sciences ◽  
Drug Formulations ◽  
Basic Studies ◽  
Constitutional Medicine ◽  
Geographical Culture

Traditional Chinese medicine (TCM), Japanese–Chinese medicine, and Korean Sasang constitutional medicine have common origins. However, the constitutional medicines of China, Japan, and Korea differ because of the influence of geographical culture, social environment, national practices, and other factors. This paper aimed to compare the constitutional medicines of China, Japan, and Korea in terms of theoretical origin, constitutional classification, constitution and pathogenesis, clinical applications and basic studies that were conducted. The constitutional theories of the three countries are all derived from the Canon of Internal Medicine or Treatise on Febrile and Miscellaneous Diseases of Ancient China. However, the three countries have different constitutional classifications and criteria. Medical sciences in the three countries focus on the clinical applications of constitutional theory. They all agree that different pathogenic laws that guide the treatment of diseases govern different constitutions; thus, patients with different constitutions are treated differently. The three countries also differ in terms of drug formulations and medication. Japanese medicine is prescribed only based on constitution. Korean medicine is based on treatment, in which drugs cannot be mixed. TCM synthesize the treatment model of constitution differentiation, disease differentiation and syndrome differentiation with the treatment thought of treating disease according to three categories of etiologic factors, which reflect the constitution as the characteristic of individual precision treatment. In conclusion, constitutional medicines of China, Japan, and Korea have the same theoretical origin, but differ in constitutional classification, clinical application of constitutional theory on the treatment of diseases, drug formulations and medication.

scholarly journals Gastrodia elata Blume Polysaccharides: A Review of Their Acquisition, Analysis, Modification, and Pharmacological Activities

Molecules ◽  
2019 ◽  
Vol 24 (13) ◽  
pp. 2436 ◽  
Author(s):  
Haodong Zhu ◽  
Chen Liu ◽  
Jinjun Hou ◽  
Huali Long ◽  
Bing Wang ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Research And Development ◽  
Qualitative Analysis ◽  
Clinical Applications ◽  
Pharmacological Activities ◽  
Gastrodia Elata ◽  
Gastrodia Elata Blume ◽  
Wide Range

Gastrodia elata Blume (G. elata) is a valuable Traditional Chinese Medicine (TCM) with a wide range of clinical applications. G. elata polysaccharides, as one of the main active ingredients of G. elata, have interesting extraction, purification, qualitative analysis, quantitative analysis, derivatization, and pharmacological activity aspects, yet a review of G. elata polysaccharides has not yet been published. Based on this, this article summarizes the progress of G. elata polysaccharides in terms of the above aspects to provide a basis for their further research and development.

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