scholarly journals Kinetic Analysis of Glycoprotein–Lectin Interactions by Label-Free Internal Reflection Ellipsometry

2008 ◽  
Vol 4 (1-2) ◽  
pp. 37-46 ◽  
Author(s):  
David W. Ralin ◽  
Shane C. Dultz ◽  
Judd E. Silver ◽  
Jeffrey C. Travis ◽  
Majlinda Kullolli ◽  
...  
Keyword(s):  
Kinetic Analysis ◽  
Internal Reflection ◽  
Label Free

scholarly journals Label-Free Imaging of Single Nanoparticles Using Total Internal Reflection-Based Leakage Radiation Microscopy

Nanomaterials ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 615
Author(s):  
Liwen Jiang ◽  
Xuqing Sun ◽  
Hongyao Liu ◽  
Ruxue Wei ◽  
Xue Wang ◽  
...  
Keyword(s):  
Total Internal Reflection ◽  
Near Field ◽  
Internal Reflection ◽  
In Situ Monitoring ◽  
Far Field ◽  
Label Free ◽  
Polystyrene Nanospheres ◽  
Leakage Radiation Microscopy ◽  
Leakage Radiation

Label-free, fast, and single nanoparticle detection is demanded for the in situ monitoring of nano-pollutants in the environment, which have potential toxic effects on human health. We present the label-free imaging of single nanoparticles by using total internal reflection (TIR)-based leakage radiation microscopy. We illustrate the imaging of both single polystyrene (PS) and Au nanospheres with diameters as low as 100 and 30 nm, respectively. As both far-field imaging and simulated near-field electric field intensity distribution at the interface showed the same characteristics, i.e., the localized enhancement and interference of TIR evanescent waves, we confirmed the leakage radiation, transforming the near-field distribution to far-field for fast imaging. The localized enhancement of single PS and Au nanospheres were compared. We also illustrate the TIR-based leakage radiation imaging of single polystyrene nanospheres with different incident polarizations. The TIR-based leakage radiation microscopy method is a competitive alternative for the fast, in situ, label-free imaging of nano-pollutants.

scholarly journals Label-Free Single-Particle Imaging of the Influenza Virus by Objective-Type Total Internal Reflection Dark-Field Microscopy

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e49208 ◽  
Author(s):  
Sawako Enoki ◽  
Ryota Iino ◽  
Nobuhiro Morone ◽  
Kunihiro Kaihatsu ◽  
Shouichi Sakakihara ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Single Particle ◽  
Total Internal Reflection ◽  
Dark Field ◽  
Internal Reflection ◽  
Label Free ◽  
Dark Field Microscopy ◽  
Particle Imaging ◽  
Single Particle Imaging ◽  
Objective Type

A label-free continuous total-internal-reflection-fluorescence-based immunosensor

2006 ◽  
Vol 357 (2) ◽  
pp. 159-166 ◽  
Author(s):  
Henrik A. Engström ◽  
Per Ola Andersson ◽  
Sten Ohlson
Keyword(s):  
Total Internal Reflection ◽  
Internal Reflection ◽  
Total Internal Reflection Fluorescence ◽  
Label Free
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