scholarly journals The Intergenerational Effects of Intermarriage

Author(s):  
Anna Tegunimataka

AbstractThis study closely examines long-term outcomes of intermarriage in Denmark in terms of children’s educational performance, studying grades from final examinations. The study uses rich register data, where families are linked across generations, and contributes to the migration literature by providing new insights into the human capital formation in inter-ethnic families. The outcomes of children of intermarriage are very much in line with the outcomes of children with two native-born Danish parents. Compared to second-generation immigrants, children of intermarriage perform substantially better, and these differences remain even when school and family-level confounders are taken into account. Moreover, this paper explores the heterogeneous character of the 2.5 generation in Denmark and studies the importance of parental country of origin. Parental country of origin is of significance for the educational performance of children from intermarriage in Denmark, as the performance of children with a non-native parent originating from countries of Africa, Asia, and Latin America is closer to that of second-generation immigrants, rather than natives. This association remains (for certain groups) when controlling for unobserved heterogeneity at the school and family level.

2019 ◽  
Vol 42 (7) ◽  
pp. 910-921 ◽  
Author(s):  
Ugur Canpolat ◽  
Duygu Kocyigit ◽  
Muhammed Ulvi Yalcin ◽  
Cem Coteli ◽  
Yusuf Ziya Sener ◽  
...  

2020 ◽  
Vol 13 (1) ◽  
pp. 97-111 ◽  
Author(s):  
Jeong Cheon Choe ◽  
Kwang Soo Cha ◽  
Jeong Gyu Lee ◽  
Jinmi Kim ◽  
Ji Yeon Shin ◽  
...  

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
U Canpolat ◽  
D Kocyigit ◽  
M U Yalcin ◽  
C Coteli ◽  
Y Z Sener ◽  
...  

Abstract Background Currently available second-generation cryoballoon (CB2) is accepted as an effective and safe tool for pulmonary vein isolation (PVI). Although much more data exists about 1-year outcomes of CB2 ablation, data on long-term outcomes are scarce. Objective: We aimed to assess the long-term outcomes of PVI using CB2 in a large-scale symptomatic AF population at our tertiary referral center. Methods In this non-randomized prospective observational study, a total of 486 patients with paroxysmal (71%) or persistent (29%) AF who underwent index PVI using CB2 at our hospital between January 2013 and June 2017 were enrolled. Atrial tachyarrhythmia (ATa) free survival was defined as absence of AF, atrial flutter or atrial tachycardia recurrence >30 s following 3-months blanking period. Predictors of recurrence were evaluated by univariate and multivariate Cox proportional hazards regression models. Results Acute procedural success rate was 99.8% (1898/1902 PVs). Mean procedural and fluoroscopy time were 64.9±9.2 and 12.1±2.6, respectively. At median 39 (IQR: 26–56) months follow-up, ATa free survival was 78.6% after a single procedure (280/345 [81.2%] for paroxysmal AF vs 102/141 [72.3%] for persistent AF, p=0.019) and 84.4% after a mean 1.48±0.42 ablations.Cox regression analysis showed that left atrium diameter, duration of AF history and early ATa recurrence were found as the independent predictors of late recurrence. PNP was observed in 17 (3.5%) patients. Figure 1 Conclusions Second-generation CB based PVI is effective to maintain sinus rhythm in a significant proportion of paroxysmal and early persistent AF patients with an acceptable complication rates at long-term follow-up.


Blood ◽  
2012 ◽  
Vol 120 (21) ◽  
pp. 2777-2777
Author(s):  
Dennis Dong Hwan Kim ◽  
Hong Gi Lee ◽  
Suzanne Kamel-Reid ◽  
Jeffrey H. Lipton

Abstract Abstract 2777 Background: The BCR/ABL transcript level at 3 months can predict long-term outcomes following frontline therapy with Imatinib or Dasatinib in chronic myeloid leukemia (CML) patients. However, data is lacking with second generation tyrosine kinase inhibitor (2GTKI) therapy after Imatinib failure. Methods: A total of 112 patients with CML in chronic phase (CP) receiving 2GTKI after Imatinib failure were reviewed. Treatment outcomes including complete cytogenetic (CCyR), major molecular (MMR) and molecular response 4.5 (MR4.5), treatment failure, progression-free (PFS) and overall survival (OS) were compared according to BCR/ABL transcript levels at 3 or 6 months, divided into <1%IS, 1–10%IS and °Ã10%IS. Results: Using cut off of 1%IS and 10%IS BCR/ABL transcript level, 70 patients (65%) showed <1%IS of BCR/ABL transcript level at 3 months, 16 patients (15%) between 1 and 10%IS, and 21 patients (20%), °Ã10%IS at 3 months. BCR/ABL transcript level at 3 months showed better correlation with OS (p<0.001) than that at 6 months (p=0.147). Better OS was also observed in the patients achieving <1%IS (100%) and 1–10%IS (100%) than those with °Ã10%IS at 3 months (70.6%, p<0.001). Those with <1%IS exhibited the best CCyR (100% at 12 months), MMR (93.1±3.2% at 18 months) and MR4.5 (80.2±6.3% at 3 years); those with 1–10%IS, intermediate (56.4±15.5% CCyR at 12 months; 22.1±14.1% MMR at 18 months; 10.0±9.5% MR4.5 at 3 years); and those with °Ã10%IS, the lowest CCyR (16.7±11.2% at 12 months), MMR (6.2±6.1% at 18 months) and MR4.5 rates (0%). Especially, in the subgroup of Imatinib resistant patients (n=59), none of them achieved MR4.5 if BCR/ABL transcript level is above 1% at 3 months (i.e. those with 1–10%IS or °Ã10%IS). Multivariate analysis confirmed strong correlation of BCR/ABL transcript level at 3 months with CCyR (HR 0.019), MMR (HR 0.047), MR4.5 (HR 0.057), treatment failure (HR 12.264), PFS (HR 7.754) and OS (HR 15.115). The group with <1%IS at 3 months maintained significantly lower BCR/ABL transcript level compared to other 2 groups. Conclusion: The BCR/ABL transcript level at 3 months is the most relevant surrogate for outcomes following 2GTKI therapy after Imatinib failure. Disclosures: No relevant conflicts of interest to declare.


2015 ◽  
Vol 87 (1) ◽  
pp. 34-40 ◽  
Author(s):  
Nagendra R. Pokala ◽  
Rohan V. Menon ◽  
Siddharth M. Patel ◽  
George Christopoulos ◽  
Georgios E. Christakopoulos ◽  
...  

2018 ◽  
Vol 107 (12) ◽  
pp. 1139-1147 ◽  
Author(s):  
Thomas Fink ◽  
Michael Schlüter ◽  
Roland Richard Tilz ◽  
Christian-Hendrik Heeger ◽  
Christine Lemes ◽  
...  

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