Graphene foam/hydrogel scaffolds for regeneration of peripheral nerve using ADSCs in a diabetic mouse model

Nano Research ◽  
2021 ◽  
Author(s):  
Qun Huang ◽  
Yuting Cai ◽  
Xinrui Yang ◽  
Weimin Li ◽  
Hongji Pu ◽  
...  
Keyword(s):  
Mouse Model ◽  
Peripheral Nerve ◽  
Diabetic Mouse ◽  
Graphene Foam ◽  
Hydrogel Scaffolds

Impaired peripheral nerve regeneration in type-2 diabetic mouse model

2018 ◽  
Vol 47 (2) ◽  
pp. 126-139 ◽  
Author(s):  
Vuong M. Pham ◽  
Nguyen Huu Tu ◽  
Tayo Katano ◽  
Shinji Matsumura ◽  
Akira Saito ◽  
...  
Keyword(s):  
Mouse Model ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Diabetic Mouse ◽  
Type 2 Diabetic

Demonstration of two different processes of beta-cell regeneration in a new diabetic mouse model induced by selective perfusion of alloxan

Diabetes ◽  
1997 ◽  
Vol 46 (8) ◽  
pp. 1281-1290 ◽  
Author(s):  
M. Waguri ◽  
K. Yamamoto ◽  
J. I. Miyagawa ◽  
Y. Tochino ◽  
K. Yamamori ◽  
...  
Keyword(s):  
Mouse Model ◽  
Beta Cell ◽  
Diabetic Mouse ◽  
Cell Regeneration ◽  
Beta Cell Regeneration ◽  
Selective Perfusion

A mitochondria-targeted near-infrared fluorescent probe for imaging viscosity in living cells and a diabetic mice model

2021 ◽  
Author(s):  
Bochao Chen ◽  
Shumei Mao ◽  
Yanyan Sun ◽  
Liyuan Sun ◽  
Ning Ding ◽  
...  
Keyword(s):  
Mouse Model ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Diabetic Mouse ◽  
Living Cells ◽  
Pancreatic Tissue ◽  
Diabetic Mice ◽  
Mice Model ◽  
Viscosity Changes

A mitochondria-targeted near-infrared fluorescent probe NIR-V with 700 nm emission was designed to monitor cell viscosity changes, which was applied to detect the intracellular viscosity and imagine pancreatic tissue in diabetic mouse model.

Pathological Alternations of Mediastinal Fat-Associated Lymphoid Cluster and Lung in a Streptozotocin-Induced Diabetic Mouse Model

2020 ◽  
pp. 1-14
Author(s):  
Yaser H.A. Elewa ◽  
Osamu Ichii ◽  
Teppei Nakamura ◽  
Yasuhiro Kon
Keyword(s):  
Endothelial Cells ◽  
Lung Injury ◽  
Mouse Model ◽  
Immune Cells ◽  
Inflammatory Markers ◽  
Inflammatory Marker ◽  
Diabetic Mouse ◽  
Control Group ◽  
Injury Progression

Diabetes is a devastating global health problem and is considered a predisposing factor for lung injury progression. Furthermore, previous reports of the authors revealed the role of mediastinal fat-associated lymphoid clusters (MFALCs) in advancing respiratory diseases. However, no reports concerning the role of MFALCs on the development of lung injury in diabetes have been published. Therefore, this study aimed to examine the correlations between diabetes and the development of MFALCs and the progression of lung injury in a streptozotocin-induced diabetic mouse model. Furthermore, immunohistochemical analysis for immune cells (CD3+ T-lymphocytes, B220+ B-lymphocytes, Iba1+ macrophages, and Gr1+ granulocytes), vessels markers (CD31+ endothelial cells and LYVE-1+ lymphatic vessels “LVs”), and inflammatory markers (TNF-α and IL-5) was performed. In comparison to the control group, the diabetic group showed lung injury development with a significant increase in MFALC size, immune cells, LVs, and inflammatory marker, and a considerable decrease of CD31+ endothelial cells in both lung and MFALCs was observed. Furthermore, the blood glucose level showed significant positive correlations with MFALCs size, lung injury, immune cells, inflammatory markers, and LYVE-1+ LVs in lungs and MFALCs. Thus, we suggest that the development of MFALCs and LVs could contribute to lung injury progression in diabetic conditions.

scholarly journals Cyclic tensile stimulation enrichment of Schwann cell-laden auxetic hydrogel scaffolds towards peripheral nerve tissue engineering

2020 ◽  
Vol 195 ◽  
pp. 108982 ◽  
Author(s):  
Yi-Wen Chen ◽  
Kan Wang ◽  
Chia-Che Ho ◽  
Chia-Tze Kao ◽  
Hooi Yee Ng ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Schwann Cell ◽  
Peripheral Nerve ◽  
Nerve Tissue ◽  
Hydrogel Scaffolds ◽  
Nerve Tissue Engineering

Specific MAPK inhibitors prevent hyperglycemia-induced renal diseases in type 1 diabetic mouse model

2016 ◽  
Vol 419 (1-2) ◽  
pp. 1-9 ◽  
Author(s):  
Zhe Hong ◽  
Zongyuan Hong ◽  
Denglong Wu ◽  
Hezhongrong Nie
Keyword(s):  
Mouse Model ◽  
Diabetic Mouse ◽  
Renal Diseases ◽  
Mapk Inhibitors

scholarly journals Silencing vimentin expression decreases pulmonary metastases in a pre-diabetic mouse model of mammary tumor progression

Oncogene ◽  
2016 ◽  
Vol 36 (10) ◽  
pp. 1394-1403 ◽  
Author(s):  
Z Zelenko ◽  
E J Gallagher ◽  
A Tobin-Hess ◽  
V Belardi ◽  
R Rostoker ◽  
...  
Keyword(s):  
Mouse Model ◽  
Tumor Progression ◽  
Mammary Tumor ◽  
Pulmonary Metastases ◽  
Diabetic Mouse ◽  
Vimentin Expression ◽  
Mammary Tumor Progression
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