scholarly journals Prospective Prescription Review System Promotes Safe Use of Analgesics, Improves Clinical Outcomes, and Saves Medical Costs in Surgical Patients: Insights from Nanjing Drum Tower Hospital

2021 ◽  
Author(s):  
Han Xie ◽  
Haixia Zhang ◽  
Jie Peng ◽  
Li Li ◽  
Yuyu Geng ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Medical Costs ◽  
Surgical Patients ◽  
Review System ◽  
Drum Tower Hospital

scholarly journals Clinical outcomes and healthcare costs of inpatients with tetanus in Korea, 2011–2019

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sohyun Bae ◽  
Minsik Go ◽  
Yoonjung Kim ◽  
Soyoon Hwang ◽  
Shin-Woo Kim ◽  
...  
Keyword(s):  
South Korea ◽  
Clinical Outcomes ◽  
Medical Costs ◽  
Common Symptom ◽  
University Hospitals ◽  
South Korean ◽  
National University ◽  
Hospital Stays ◽  
Serious Disease ◽  
Vaccination Completion

Abstract Background Tetanus is a rare, vaccine-preventable but extremely serious disease. We investigated the recent trend of the clinical outcomes and medical costs for inpatients with tetanus in South Korea over 10 years. Methods We conducted a retrospective review to determine the clinical factors and medical costs associated with tetanus at two national university hospitals in South Korea between January 2011 and October 2019. Results Forty-nine patients were admitted for tetanus (mean age, 67.0 years [range, 53.0–80.0 years]; 32 women [57.1%]). All the patients had generalized tetanus, and 5 (10.2%) died during hospitalization. The median duration from symptom onset to hospital admission was 4 days. Trismus (85.7%) was the most common symptom, and the median hospital stay was 39 days. Thirty-two patients (65.3%) required mechanical ventilation, and 20 (40.8%) developed aspiration pneumonia. The median total healthcare cost per patient was US $18,011. After discharge, 35 patients (71.4%) recovered sufficiently to walk without disability. Conclusions Tetanus requires long hospital stays and high medical expenditures in South Korea; however, the vaccination completion rate is low. Medical staff should therefore promote medical advice and policies on the management of tetanus to the general South Korean population.

Clinical Outcomes and Medical Costs of Hydration Therapy with Hydroxyethyl Starch (130/0.4) or Acute Single Infarction

2021 ◽  
Vol 30 (5) ◽  
pp. 105705
Author(s):  
Ayaka Fujita ◽  
Masashi Matsuzaka ◽  
Norifumi Metoki ◽  
Joji Hagii ◽  
Hiroshi Shiroto ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Hydroxyethyl Starch ◽  
Medical Costs ◽  
Hydration Therapy

Feed Abdominal Surgery Patients to Improve Outcomes

2021 ◽  
Vol 66 (6) ◽  
pp. 158-160
Author(s):  
Laura Bolton
Keyword(s):  
Abdominal Surgery ◽  
Clinical Outcomes ◽  
Postoperative Morbidity ◽  
Oral Feeding ◽  
The Other ◽  
Surgical Patients ◽  
Electrolyte Balance ◽  
Considerable Research ◽  
Balance Energy ◽  
The Subject

Malnourishment of surgical patients has long been recognized as contributing to postoperative morbidity and mortality.1,2 Early protocols calling for lengthy perioperative patient fasting have been replaced by interventions aimed at diagnosing and addressing each patient’s nutritional and metabolic needs; maintaining fluid and electrolyte balance, energy, and protein stores; and preserving muscle strength and gut microbiome by restoring oral feeding as soon as possible postoperatively.3 Interventions to achieve this physiologic balance have been the subject of considerable research, yet neither comprehensive preoperative programs4 nor early postoperative oral feeding5 have been reported to result in consistently improved clinical outcomes following abdominal surgery. This installment of Evidence Corner explores 2 systematic reviews, one of which presents clinical outcomes of early resumption of enteral food intake within 24 hours after gastrointestinal (GI) surgery,6 and the other presents clinical outcomes of perioperatively enhanced nutrition for those undergoing radical cystectomy (RC) for bladder cancer.7

Prognostic factors and long-term clinical outcomes for surgical patients with intestinal Behcetʼs disease

2011 ◽  
Vol 17 (7) ◽  
pp. 1594-1602 ◽  
Author(s):  
Yoon Suk Jung ◽  
Jin Young Yoon ◽  
Jin Ha Lee ◽  
Soung Min Jeon ◽  
Sung Pil Hong ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Clinical Outcomes ◽  
Surgical Patients

scholarly journals Relationship Between The Appropriateness of Antibiotic Treatment and Clinical Outcomes of Patients With Community-Acquired Acute Pyelonephritis: A Multicenter Prospective Cohort Study

2021 ◽  
Author(s):  
Choseok Yoon ◽  
Se Yoon Park ◽  
Bongyoung Kim ◽  
Ki Tae Kwon ◽  
Seong-yeol Ryu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Clinical Outcomes ◽  
Antibiotic Treatment ◽  
Prospective Cohort Study ◽  
Acute Pyelonephritis ◽  
Prospective Cohort ◽  
Clinical Symptoms ◽  
Medical Costs ◽  
Multicenter Prospective Cohort Study ◽  
Multicenter Prospective Cohort

Abstract Background Inappropriate use of antibiotics not only increases antibiotic resistance as collateral damage but also increases clinical failure rates and medical costs. The purpose of this study was to determine the relationship between the appropriateness of antibiotic prescription and clinical outcomes of community-acquired acute pyelonephritis (CA-APN). Methods A multicenter prospective cohort study was conducted at eight hospitals in Korea between September 2017 and August 2018. All hospitalized patients aged ≥ 19 years who were diagnosed with CA-APN on admission were recruited. The appropriateness of empirical and definitive antibiotics, as well as the appropriateness of antibiotic treatment duration and route of administration, was evaluated. Clinical outcomes were compared between patients who were administered antibiotics ‘appropriately’ and ‘inappropriately.’ Results A total of 397 and 318 patients were eligible for the analysis of the appropriateness of empirical and definitive antibiotics, respectively. Of them, 10 (2.5%) and 18 (5.7%) were administered ‘inappropriately’ empirical and definitive antibiotics, respectively. Of the 119 patients whose use of both empirical and definitive antibiotics was classified as ‘optimal,’ 57 (47.9%) received antibiotics over a longer duration than that recommended; 67 (56.3%) did not change to oral antibiotics on day 7 of hospitalization, even after stabilization of the clinical symptoms. Patients who were administered empirical antibiotics ‘appropriately’ had shorter hospitalization days (9 vs. 12.5 days, P = 0.014) and lower medical costs (2,332.7 vs. 4,531.2 USD, P = 0.007) than those who were administered them ‘inappropriately.’ Similar findings were observed for patients administered both empirical and definitive antibiotics ‘appropriately’ and those administered either empirical or definitive antibiotics ‘inappropriately’ Conclusions Appropriate use of antibiotics leads to better clinical outcomes, including reduced hospitalization duration and medical costs.

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