First Detection of Human Papillomaviruses and Human Polyomaviruses in River Waters in Italy

2015 ◽  
Vol 7 (4) ◽  
pp. 309-315 ◽  
Author(s):  
M. Iaconelli ◽  
S. Petricca ◽  
S. Della Libera ◽  
P. Di Bonito ◽  
G. La Rosa
Virology ◽  
2014 ◽  
Vol 468-470 ◽  
pp. 244-247 ◽  
Author(s):  
Maria Bradley ◽  
Cecilia Nordfors ◽  
Andrea Vlastos ◽  
Giovanni Ferrara ◽  
Torbjörn Ramqvist ◽  
...  

2019 ◽  
Vol 59 (1) ◽  
pp. 28-32
Author(s):  
Torbjörn Ramqvist ◽  
Christian Ortiz-Villalon ◽  
Eva Brandén ◽  
Hirsh Koyi ◽  
Luigi de Petris ◽  
...  

2003 ◽  
Vol 16 (3) ◽  
pp. 283-288 ◽  
Author(s):  
D. Fioriti ◽  
V. Pietropaolo ◽  
S. Dal Forno ◽  
C. Laurenti ◽  
F. Chiarini ◽  
...  

Bladder cancer is the second most commonly occurring genitourinary cancer in adults. The interaction of different carcinogenic and co-carcinogenic agents are responsible for bladder urothelial carcinoma: alcohol and smoking habits, Schistosoma haematobium infection, exposition to chemicals, analgesic and antineoplastic drugs prolonged use. Recently also viral infections have been associated to this pathology. In this study the correlation between viral infections and bladder carcinoma has been evaluated. A group of 32 patients affected by primary bladder neoplasia has been analysed. A control group of 20 autoptic samples of healthy bladder was analysed. The DNA of the following viruses has been searched by Polymerase chain reaction (PCR): Adenovirus, Herpes simplex virus type 1 (HSV-1), Herpes simplex virus type 2 (HSV-2), Human Papillomaviruses (HPV), Polyomaviruses (BKV and JCV). In the examined population the association bladder carcinoma-HPV, found by others, has not been confirmed. The high percentage of human polyomaviruses present in the samples is a statistically significant data (p=0.0087) and allows to presume that BKV and JCV may play a role in the aetiology of bladder tumor. In particular the polyomavirus BK, which is found in significative percentage both in single infection (p=0.0036) and in co-infections with other viral species (p=0.035), may be an important co-factor in the pathogenesis of bladder carcinoma.


2013 ◽  
Vol 3 (4) ◽  
pp. 234 ◽  
Author(s):  
Eunsim Shin ◽  
Heojin Bae ◽  
Wan-Keun Song ◽  
Sun-Kyung Jung ◽  
Yoo-Sung Hwang

2020 ◽  
Vol 75 (3) ◽  
pp. 189-195
Author(s):  
Vladislav I. Krasnopolsky ◽  
Nina V. Zarochentseva ◽  
Ksenia V. Krasnopolskaya ◽  
Yulia N. Bashankaeva ◽  
Varvara S. Kuzmicheva

The purpose of the review a synthesis of research data on the role of human papillomavirus infection in the reproductive health of women and men. Key Points. Human papillomavirus (HPV) is one of the most common sexually transmitted viruses worldwide. According to the World Health Organization, HPV is the main cause of the development of HPV-associated diseases among both women and men. Viruses are subdivided into HPV with low carcinogenic risk, which cause benign warts, and HPV with high carcinogenic risk, which cause cancer. Different types of human papillomaviruses depending on their characteristic tropism, are divided into skin and mucous types. Viral infection in men leads to a decrease in the quality of sperm (for example, asthenozoospermia) due to apoptosis in sperm cells and due to the development of antisperm immunity. A negative viral effect on the fertility of women is manifested in an increase in the frequency of spontaneous miscarriages and a premature rupture of the amniotic membranes during pregnancy. There is evidence that HPV decreases the number of trophoblastic cells and abnormal trophoblastic-endometrial adhesion is also observed. In trophoblastic cells transfected with high-risk HPV, the level of apoptosis increases. HPV vaccination is safe, and the results show not only protection against HPV-associated diseases in women and men, but also a reduction of gestational complications, reduced preterm birth rates and the protection of newborns from infection.


2019 ◽  
Vol 13 (2) ◽  
pp. 52-58
Author(s):  
V. B. Korobov ◽  
I. V. Miskevich ◽  
A. S. Lokhov ◽  
K. A. Seredkin

Abstract: pH is one of the most important parameters characterizing the state of water systems. The arithmetic mean values of samples are often used when averaging serial pH measurements in water bodies, as is usually done for other characteristics of the state of the natural environment (temperature, salinity, oxygen concentrations, suspended solids, etc.). However, in this case such an operation is illegal, since the addition of logarithms, which by definition are pH, is non-additive. The authors conducted a study to determine the extent to which pH variability in natural objects such an operation would not distort the results. For this, several samples of the pH index were generated in various ranges of its theoretically possible and natural variability. It was established that with pH variability of less than a unit characteristic of marine pH values, the statistical characteristics of the indicator and [H+ ] concentrations differ slightly, and the medians of the samples coincide. It is concluded that with such ranges characteristic of the waters of the oceans, there is no need to recalculate previously obtained results. However, for the estuaries of rivers flowing into tidal seas, as shown by field measurements, the pH variability in the mixing zone of sea and river waters is several times higher. Similar situations may occur when heavy precipitation falls on the water surface, as well as during floods. In these cases, a simple averaging of the pH values will no longer be correct. In such cases, the use of other averaging algorithms and the choice of stable statistical characteristics are required.


Author(s):  
Karim Nagi ◽  
Ishita Gupta ◽  
Hamda A Al-Thawadi ◽  
Ayesha Jabeen ◽  
Mohammed I. Malk ◽  
...  

Background: Several studies have shown the presence of onco viral DNA in colorectal tumor tissues. Viral infection by onco-viruses such as Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV) are well-known to be involved in the onset and/or progression of numerous human carcinomas. Methods: We explored the co-presence of high-risk HPVs and EBV in a cohort of colorectal cancer samples from Lebanon (94) and Syria (102) by PCR, immunohistochemistry and tissue microarray. Results: The results of the study point out that 54% of colorectal cancer cases in Syria are positive for high-risk HPVs, while 30% of the cases in Lebanon are positive for these viruses; the most frequent high-risk HPV types in these populations are 16, 18, 31, 33 and 35. Analysis of LMP1 showed similar results in both populations; 36% of Syrian and 31% of Lebanese samples. Additionally, we report that EBV and high-risk HPVs are co-present in these samples. In Syrian samples, EBV and HPVs are co-present in 16% of the population, however, in the Lebanese samples, 20% of the cases are positive for both EBV and HPVs; their co-presence is associated with high/intermediate grade invasive carcinomas. Conclusion: These data suggest that EBV and high-risk HPVs are co-present in human colorectal cancers where they can cooperate in the progression of these cancers. Nevertheless, further studies are needed to elucidate the role of those oncoviruses in the development of human colorectal carcinomas.


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