scholarly journals Molecular approach for detecting early prepatent Schistosoma mansoni infection in Biomphalaria alexandrina snail host

2014 ◽  
Vol 40 (3) ◽  
pp. 805-812 ◽  
Author(s):  
Adel Farghaly ◽  
Ayman A. Saleh ◽  
Soad Mahdy ◽  
Dalia Abd El-Khalik ◽  
Naglaa F. Abd El-Aal ◽  
...  
Keyword(s):  
Schistosoma Mansoni ◽  
Snail Host ◽  
Molecular Approach ◽  
Biomphalaria Alexandrina

Spotlight on the in vitro effect of artemisinin–naphthoquine phosphate on Schistosoma mansoni and its snail host Biomphalaria alexandrina

Acta Tropica ◽  
2015 ◽  
Vol 141 ◽  
pp. 37-45 ◽  
Author(s):  
Samar N. El-Beshbishi ◽  
Samia El Bardicy ◽  
Menerva Tadros ◽  
Magda Ayoub ◽  
Amira Taman
Keyword(s):  
Schistosoma Mansoni ◽  
Snail Host ◽  
Biomphalaria Alexandrina ◽  
Vitro Effect

Ultrastructural analysis of “Sensory” surface nerve endings and “putative” neurotransmitter sites in Schistosoma mansoni Miracidia

1989 ◽  
Vol 47 ◽  
pp. 962-963
Author(s):  
Betty Ruth Jones ◽  
Steve Chi-Tang Pan
Keyword(s):  
Nervous System ◽  
Life Cycle ◽  
Schistosoma Mansoni ◽  
Snail Host ◽  
Complex Life Cycle ◽  
Rational Approach ◽  
Effective Control ◽  
The Social ◽  
Social And Economic Development ◽  
Basic Biology

INTRODUCTION: Schistosomiasis has been described as “one of the most devastating diseases of mankind, second only to malaria in its deleterious effects on the social and economic development of populations in many warm areas of the world.” The disease is worldwide and is probably spreading faster and becoming more intense than the overall research efforts designed to provide the basis for countering it. Moreover, there are indications that the development of water resources and the demands for increasing cultivation and food in developing countries may prevent adequate control of the disease and thus the number of infections are increasing.Our knowledge of the basic biology of the parasites causing the disease is far from adequate. Such knowledge is essential if we are to develop a rational approach to the effective control of human schistosomiasis. The miracidium is the first infective stage in the complex life cycle of schistosomes. The future of the entire life cycle depends on the capacity and ability of this organism to locate and enter a suitable snail host for further development, Little is known about the nervous system of the miracidium of Schistosoma mansoni and of other trematodes. Studies indicate that miracidia contain a well developed and complex nervous system that may aid the larvae in locating and entering a susceptible snail host (Wilson, 1970; Brooker, 1972; Chernin, 1974; Pan, 1980; Mehlhorn, 1988; and Jones, 1987-1988).

Energy constraint exerted by the parasite Schistosoma mansoni on the locomotion of its snail host, Biomphalaria glabrata

1996 ◽  
Vol 74 (4) ◽  
pp. 594-598 ◽  
Author(s):  
Claudia Gérard
Keyword(s):  
Resource Allocation ◽  
Schistosoma Mansoni ◽  
Biomphalaria Glabrata ◽  
Snail Host ◽  
Locomotory Activity ◽  
Patent Period ◽  
Energy Constraint

The consequences of the constraint caused by the parasite Schistosoma mansoni on the locomotory activity of its snail host, Biomphalaria glabrata, were studied during the patent period. Rates of locomotion were determined 6 times per 24-h period for juvenile and adult snails with single-miracidium infections, then compared with those of healthy snails of the same age. The locomotory activity of infected snails was the same during the day and at night, whereas control snails moved less at night than during the day. The locomotion of snails infected when immature was similar to that of the controls during the day and superior at night. The locomotion of snails infected when mature decreased regularly during patency and clearly decreased in comparison with that of healthy snails. The results are interpreted in terms of energy constraint on the mode of resource allocation of the host due to the parasite.

scholarly journals A metalloprotease produced by larval Schistosoma mansoni facilitates infection establishment and maintenance in the snail host by interfering with immune cell function

2018 ◽  
Vol 14 (10) ◽  
pp. e1007393 ◽  
Author(s):  
Jacob R. Hambrook ◽  
Alèthe L. Kaboré ◽  
Emmanuel A. Pila ◽  
Patrick C. Hanington
Keyword(s):  
Schistosoma Mansoni ◽  
Cell Function ◽  
Immune Cell ◽  
Snail Host ◽  
Immune Cell Function

scholarly journals Experimental infection with Schistosoma mansoni of Biomphalaria straminea from different parts of the Northeast of Brazil

1986 ◽  
Vol 28 (3) ◽  
pp. 160-165 ◽  
Author(s):  
E. A. Malek ◽  
M. Z. Rouquayrol
Keyword(s):  
Schistosoma Mansoni ◽  
Puerto Rican ◽  
Experimental Infection ◽  
Snail Host ◽  
The State ◽  
Infection Rates ◽  
Biomphalaria Straminea ◽  
Albino Strain ◽  
Very High ◽  
Different Parts

In the western part of the State of Bahia Biomphalaria straminea and B. glabrata both occur, but in the majority of cases they do not share the same habitat. In the State of Ceará, however, B. straminea is the sole snail host of Schistosoma mansoni. In this survey, no naturally infected B. straminea was found among snails collected from Bahia and Ceará, evidently because of the very low infection rates. The susceptibility of laboratory-reared specimens to infection with a Puerto Rican strain of S. mansoni was then tested experimentally. In general, the snails showed very low susceptibility. The infection rates were 1.1% among snails from Redenção (Ceará); 2.3% in those from Pentecoste (Ceará); 2.9% in snails from São Desidério (Bahia), while they were very high among an albino strain (NIH) of B. glabrata used as control. Another group of B. straminea from São Desidério was exposed to a Bahian strain of S. mansoni and the infection rate was still very low (3.6%) Apparently, the very low susceptibility of B. straminea, despite high snail density, is correlated with moderate infection rates with S. mansoni among humans, as shown by the results of stool examinations conducted by SUCAM in the municipalities of Redenção and Pentecoste, in Ceará.

scholarly journals Efficacy of Miltefosine and Artemether on infected Biomphalaria alexandrina snails with Schistosoma mansoni: immunological and histological studies

2020 ◽  
Vol 57 (4) ◽  
pp. 335-343
Author(s):  
H. H. Abdel-Azeem ◽  
G. Y. Osman ◽  
M. F. El Garhy ◽  
K. S. Al Benasy
Keyword(s):  
Electron Microscopy ◽  
Schistosoma Mansoni ◽  
Light And Electron Microscopy ◽  
Post Treatment ◽  
Sublethal Dose ◽  
Biomphalaria Alexandrina ◽  
Histological Studies ◽  
Morphological Abnormalities ◽  
Medical Importance

SummaryBiomphalaria alexandrina snails have received much attention due to their great medical importance as vectors for transmitting Schistosoma mansoni infection to humans. The main objective of the present work was to assess the efficacy of miltefosin a synthetic molluscicidal drug and artemether a natural molluscicidal drug. The correlation between immunological and histological observations from light and electron microscopy of the hemocytes of B. alexandrina post treatment with both drugs was also evaluated. LC50 and LC90 values were represented by 13.80 ppm and 24.40 ppm for miltefosine and 16.88 ppm and 27.97 ppm for artemether, respectively. The results showed that the treatment of S. mansoni-infected snails and normal snails with sublethal dose of miltefosine (LC25=8.20 ppm) and artemether (LC25=11.04 ppm) induced morphological abnormalities and a significant reduction in hemocytes count.

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