Powder lemon juice containing oligosaccharides obtained by dextransucrase acceptor reaction synthesis and dehydrated in sprouted bed

The purpose of this study was to determine the optimal ratio of carbonated aloe vera drink and lemon juice. This research used completely randomized design with four treatments and four replications. The treatments performed were L1 (90% carbonated aloe vera and 10% lemon juice), L2 (80% carbonated aloe vera and 20% lemon juice), L3 (70% carbonated aloe vera and 30% lemon juice), and L4 (60% carbonated aloe vera and 40% lemon juice). Data were statistically analyzed by using analysis of variance (ANOVA) and followed by duncan new multiple range test (DNMRT) at level 5%. The combination treatments of carbonated aloe vera drinks and lemon juice had a significant effect on acidity (pH), vitamin C, total dissolved solids, and descriptive and hedonic sensory assessment. The best treatment from the research was L3 (70% carbonated aloe vera and 30% lemon juice) with pH of 4.26, vitamin C of 19.97 mg, and total dissolved solids of 14.34°brix. The overall sensory test result preferred by panelists with descriptions of yellow color, lemon flavor, and had a slightly sweet taste.

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Lemon Juice Mediated Synthesis of 3-Substituted Quinazolin-4(3H)-Ones and their Pharmacological Evaluation

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871520619666190723151909 ◽

2020 ◽

Vol 19 (16) ◽

pp. 2001-2009 ◽

Cited By ~ 1

Author(s):

Malavattu G. Prasad ◽

C. Vijaya Lakshmi ◽

Naresh K. Katari ◽

Sreekantha B. Jonnalagadda ◽

Manojit Pal

Keyword(s):

Cell Line ◽

Cell Lines ◽

Hek293 Cell ◽

Glyoxylic Acid ◽

Lemon Juice ◽

Cytotoxic Agents ◽

Diverse Range ◽

Hek293 Cell Line ◽

Three Component Reaction ◽

Mcf 7

Background: Compounds containing the quinazoline-4(3H)-one framework constitute an important class of fused N-heterocycles that are found in more than 200 naturally occurring alkaloids. These compounds also show a diverse range of pharmacological activities including antitumor properties. This prompted us to explore a series of quinazolin-4-(3H)-one derivatives having no substituent at C-2 as potential cytotoxic agents. Objective: The objective of this study was to synthesize and evaluate 3-substituted quinazolin-4(3H)-one derivatives for their potential cytotoxic properties. Methods: A convenient method has been developed for the rapid synthesis of this class of compounds under a mild and non-hazardous reaction condition in good yields. The methodology involved a three-component reaction employing isatoic anhydride, amines and glyoxylic acid as reactants in the presence of lemon juice in PEG- 400 at room temperature (25-30ºC) under ultrasound irradiation. All the synthesized compounds were screened via an MTT assay for their potential cytotoxic properties in vitro using the cancerous cell lines e.g. A549, A2780, HepG2, K562, MCF-7 and HCT-116 and a non-cancerous HEK293 cell line. Results: Several compounds such as 3a, 3b, 3d, 3e and 3f showed promising growth inhibition against these cancer cell lines but no significant effects on HEK293 cell line. The IC50 values of these compounds were comparable to doxorubicin whereas 3f significantly induced apoptosis in MCF-7 cells that also was comparable to doxorubicin. Conclusion: An ultrasound-assisted MCR facilitated by lemon juice has been developed to synthesize 3- substituted quinazolin-4(3H)-one derivatives that could act as potential anticancer agents.

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Green synthesis of crystalline bismuth nanoparticles using lemon juice

RSC Advances ◽

10.1039/d1ra03560f ◽

2021 ◽

Vol 11 (43) ◽

pp. 26683-26686

Author(s):

Md. Mahiuddin ◽

Bungo Ochiai

Keyword(s):

Green Synthesis ◽

Aqueous Media ◽

Cost Effective ◽

Lemon Juice ◽

Capping Agent ◽

Bismuth Nanoparticles

Lemon juice effectively served as a reducing and capping agent for an easy, cost-effective, and green synthesis of crystalline bismuth nanoparticles (BiNPs) in basic aqueous media.

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