Addition of olive (olea europaea) leaf extract as a source of natural antioxidant in mutton meatball stored at refrigeration temperature

2020 ◽  
Author(s):  
Saju Ahmed Rubel ◽  
Z. N. Yu ◽  
H. M. Murshed ◽  
S. M. Ariful Islam ◽  
Dalia Sultana ◽  
...  
Keyword(s):  
Olea Europaea ◽  
Leaf Extract ◽  
Natural Antioxidant ◽  
Olea Europaéa

Olea europaea leaf extract alters microRNA expression in human glioblastoma cells

2012 ◽  
Vol 138 (11) ◽  
pp. 1831-1844 ◽  
Author(s):  
Berrin Tunca ◽  
Gulcin Tezcan ◽  
Gulsah Cecener ◽  
Unal Egeli ◽  
Secil Ak ◽  
...  
Keyword(s):  
Olea Europaea ◽  
Leaf Extract ◽  
Microrna Expression ◽  
Glioblastoma Cells ◽  
Human Glioblastoma ◽  
Human Glioblastoma Cells ◽  
Olea Europaéa

Olea europaea leaf extract and bevacizumab synergistically exhibit beneficial efficacy upon human glioblastoma cancer stem cells through reducing angiogenesis and invasion in vitro

2017 ◽  
Vol 90 ◽  
pp. 713-723 ◽  
Author(s):  
Gulcin Tezcan ◽  
Mevlut Ozgur Taskapilioglu ◽  
Berrin Tunca ◽  
Ahmet Bekar ◽  
Hilal Demirci ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Olea Europaea ◽  
Leaf Extract ◽  
Human Glioblastoma ◽  
Olea Europaéa

Standardized Olea europaea L. leaf extract exhibits protective activity in carbon tetrachloride-induced acute liver injury in rats: the insight into potential mechanisms

2019 ◽  
Vol 126 (5) ◽  
pp. 399-407 ◽  
Author(s):  
Sašenka Vidičević ◽  
Jelena Tošić ◽  
Željka Stanojević ◽  
Aleksandra Isaković ◽  
Dragana Mitić ◽  
...  
Keyword(s):  
Carbon Tetrachloride ◽  
Liver Injury ◽  
Olea Europaea ◽  
Leaf Extract ◽  
Acute Liver Injury ◽  
Protective Activity ◽  
Olea Europaea L ◽  
Insight Into ◽  
Olea Europaéa

scholarly journals Green fabricated CuO nanobullets via Olea europaea leaf extract shows auspicious antimicrobial potential

2017 ◽  
Vol 11 (4) ◽  
pp. 463-468 ◽  
Author(s):  
Qaisar Maqbool ◽  
Sidra Iftikhar ◽  
Mudassar Nazar ◽  
Fazal Abbas ◽  
Asif Saleem ◽  
...  
Keyword(s):  
Olea Europaea ◽  
Leaf Extract ◽  
Antimicrobial Potential ◽  
Olea Europaéa

Use of a methanolic olive leaf extract (Olea europaea) against white spot virus syndrome in Penaeus vannamei: Comparing the biochemical, hematological and immunological changes

Aquaculture ◽  
2020 ◽  
Vol 528 ◽  
pp. 735556 ◽  
Author(s):  
Amin Gholamhosseini ◽  
Mohammad Reza Kheirandish ◽  
Nima Shiry ◽  
Mostafa Akhlaghi ◽  
Siyavash Soltanian ◽  
...  
Keyword(s):  
Olea Europaea ◽  
Leaf Extract ◽  
White Spot ◽  
Penaeus Vannamei ◽  
Olive Leaf ◽  
Spot Virus ◽  
Olive Leaf Extract ◽  
Immunological Changes ◽  
Olea Europaéa

Oleuropein modulates glioblastoma miRNA pattern different from Olea europaea leaf extract

2019 ◽  
Vol 38 (9) ◽  
pp. 1102-1110 ◽  
Author(s):  
G Tezcan ◽  
SA Aksoy ◽  
B Tunca ◽  
A Bekar ◽  
M Mutlu ◽  
...  
Keyword(s):  
Cell Line ◽  
Olea Europaea ◽  
Leaf Extract ◽  
Antitumour Effect ◽  
Main Compound ◽  
Therapeutic Modalities ◽  
Polymerase Chain ◽  
Minor Compounds ◽  
Post Hoc ◽  
Olea Europaéa

Glioblastoma (GBM) is the most prevalent and deadliest subtype of glioma. Despite current innovations in existing therapeutic modalities, GBM remains incurable, and alternative therapies are required. Previously, we demonstrated that Olea europaea leaf extract (OLE) kills GBM cells by modulating miR-181b, miR-137, miR-153 and Let-7d expression. However, although oleuropein (OL) is the main compound in OLE, its role in the antitumour effect of OLE remains unknown. This study determined the effect of OL on GBM cell line T98G and compared the results with our previous findings regarding the effect of OLE on the same cell line. The antiproliferative activity of OL and its effect on temozolomide (TMZ) response were tested inT98G cells using WST-1 assay. OL inhibition was evaluated using one-way analysis of variance with Tukey’s post hoc test. The effect of OL on miR-181b, miR-137, miR-153 and Let-7d expression was assessed using quantitative reverse transcription polymerase chain reaction. Fold differences in expression between untreated, OL or OL + TMZ-treated samples were calculated using 2−ΔCt method. Significance was evaluated using an independent sample t-test. Treatment with 277.5 and 555 µM OL resulted in 39.51% and 75.40% reductions in T98G cells within 24 h. Coadministration of 325 µM TMZ and 277.5 or 555 µM, OL caused 2.08- and 2.83-fold increases, respectively, in the therapeutic effect of TMZ. OL + TMZ significantly increased microRNA expression, particularly Let-7d, than OLE. In conclusion, OL has an antitumour effect on GBM cells mainly via regulation of Let-7d expression. The present results also indicate other minor compounds in OLE play important anticancer roles.

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