XPD, APE1, and MUTYH polymorphisms increase head and neck cancer risk: effect of gene-gene and gene-environment interactions

Tumor Biology ◽  
2015 ◽  
Vol 36 (10) ◽  
pp. 7569-7579 ◽  
Author(s):  
Sambuddha Das ◽  
Aditi Bhowmik ◽  
Abhinandan Bhattacharjee ◽  
Biswadeep Choudhury ◽  
Momota Naiding ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Gene Environment ◽  
Risk Effect

scholarly journals Impacts of Environmental Factors on Head and Neck Cancer Pathogenesis and Progression

Cells ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 389
Author(s):  
Marisol Miranda-Galvis ◽  
Reid Loveless ◽  
Luiz Paulo Kowalski ◽  
Yong Teng
Keyword(s):  
Head And Neck Cancer ◽  
Environmental Factors ◽  
Head And Neck ◽  
Neck Cancer ◽  
Molecular Mechanisms ◽  
Metastatic Cancer ◽  
Environmental Drivers ◽  
Cancer Pathogenesis ◽  
Gene Environment ◽  
The Impact

Epidemiological and clinical studies over the past two decades have provided strong evidence that genetic elements interacting with environmental components can individually and collectively influence one’s susceptibility to cancer. In addition to tumorigenic properties, numerous environmental factors, such as nutrition, chemical carcinogens, and tobacco/alcohol consumption, possess pro-invasive and pro-metastatic cancer features. In contrast to traditional cancer treatment, modern therapeutics not only take into account an individual’s genetic makeup but also consider gene–environment interactions. The current review sharpens the focus by elaborating on the impact that environmental factors have on the pathogenesis and progression of head and neck cancer and the underlying molecular mechanisms involved. Recent advances, challenges, and future perspectives in this area of research are also discussed. Inhibiting key environmental drivers of tumor progression should yield survival benefits for patients at any stage of head and neck cancer.

scholarly journals A Case-Control Study on the Effect of Apoliprotein E Genotype on Head and Neck Cancer Risk

2010 ◽  
Vol 19 (11) ◽  
pp. 2839-2846 ◽  
Author(s):  
Emma De Feo ◽  
Jessica Rowell ◽  
Gabriella Cadoni ◽  
Nicola Nicolotti ◽  
Dario Arzani ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk

Head & Neck ◽  
2012 ◽  
Vol 35 (6) ◽  
pp. 858-867 ◽  
Author(s):  
Martin Lacko ◽  
Adri C. Voogd ◽  
Hennie M. J. Roelofs ◽  
Rene H. M. te Morsche ◽  
Michel B. Oude Ophuis ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Phase I ◽  
Head And Neck ◽  
Genetic Polymorphisms ◽  
Neck Cancer ◽  
Combined Effect ◽  
Biotransformation Enzymes ◽  
Phase I And Ii

scholarly journals Dietary glycaemic index, glycaemic load and head and neck cancer risk: a pooled analysis in an international consortium

2020 ◽  
Vol 122 (6) ◽  
pp. 745-748 ◽  
Author(s):  
Chun-Pin Chang ◽  
Carlo La Vecchia ◽  
Diego Serraino ◽  
Andrew F. Olshan ◽  
Jose P. Zevallos ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Glycaemic Index ◽  
Pooled Analysis ◽  
International Consortium ◽  
Glycaemic Load

scholarly journals No association of TNF-α-308G/A polymorphisms with head and neck cancer risk

Medicine ◽  
2017 ◽  
Vol 96 (25) ◽  
pp. e7298 ◽  
Author(s):  
Cheng Yuan ◽  
Xin-Hua Xu ◽  
Lu Xu ◽  
Yang Liu ◽  
Min Sun ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Tnf Α

How much do smoking and alcohol consumption explain socioeconomic inequalities in head and neck cancer risk?

2010 ◽  
Vol 65 (8) ◽  
pp. 709-714 ◽  
Author(s):  
A. F. Boing ◽  
J. L. F. Antunes ◽  
M. B. de Carvalho ◽  
J. F. de Gois Filho ◽  
L. P. Kowalski ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Alcohol Consumption ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Socioeconomic Inequalities

scholarly journals Alcohol drinking and head and neck cancer risk: the joint effect of intensity and duration

2020 ◽  
Vol 123 (9) ◽  
pp. 1456-1463
Author(s):  
Gioia Di Credico ◽  
Jerry Polesel ◽  
Luigino Dal Maso ◽  
Francesco Pauli ◽  
Nicola Torelli ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Alcohol Drinking ◽  
Joint Effect

scholarly journals Osteoradionecrosis of the mandible after radiotherapy for head and neck cancer: risk factors and dose-volume correlations

2019 ◽  
Vol 58 (10) ◽  
pp. 1373-1377 ◽  
Author(s):  
S. Aarup-Kristensen ◽  
C. R. Hansen ◽  
L. Forner ◽  
C. Brink ◽  
J. G. Eriksen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Cancer Risk Factors ◽  
Dose Volume

scholarly journals Hormone factors play a favorable role in female head and neck cancer risk

2017 ◽  
Vol 6 (8) ◽  
pp. 1998-2007 ◽  
Author(s):  
Dana Hashim ◽  
Samantha Sartori ◽  
Carlo La Vecchia ◽  
Diego Serraino ◽  
Luigino Dal Maso ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Risk ◽  
Head And Neck ◽  
Neck Cancer ◽  
Female Head
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