scholarly journals The effects of a high-caloric protein-rich oral nutritional supplement in patients with chronic heart failure and cachexia on quality of life, body composition, and inflammation markers: a randomized, double-blind pilot study

2010 ◽  
Vol 1 (1) ◽  
pp. 35-42 ◽  
Author(s):  
Piotr Rozentryt ◽  
Stephan von Haehling ◽  
Mitja Lainscak ◽  
Jolanta U. Nowak ◽  
Kamyar Kalantar-Zadeh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Body Composition ◽  
Pilot Study ◽  
Chronic Heart Failure ◽  
Nutritional Supplement ◽  
Inflammation Markers ◽  
Double Blind ◽  
Protein Rich

A double-blind placebo-controlled pilot study of controlled-release paroxetine on depression and quality of life in chronic heart failure

2007 ◽  
Vol 153 (5) ◽  
pp. 868-873 ◽  
Author(s):  
Stephen S. Gottlieb ◽  
Willem J. Kop ◽  
Sue A. Thomas ◽  
Scott Katzen ◽  
Mark R. Vesely ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Pilot Study ◽  
Controlled Release ◽  
Chronic Heart Failure ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Acceptability, Feasibility and Preliminary Evaluation of a Novel, Personalised, Home-Based Physical Activity Intervention for Chronic Heart Failure (Active-at-Home-HF): a Pilot Study

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Nduka C. Okwose ◽  
Leah Avery ◽  
Nicola O’Brien ◽  
Sophie Cassidy ◽  
Sarah J. Charman ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Heart Failure ◽  
Pilot Study ◽  
Chronic Heart Failure ◽  
Physical Activity Intervention ◽  
Step Count ◽  
Home Based ◽  
At Home

Abstract Purpose Less than 10% of heart failure patients in the UK participate in cardiac rehabilitation programmes. The present pilot study evaluated feasibility, acceptability and physiological effects of a novel, personalised, home-based physical activity intervention in chronic heart failure. Methods Twenty patients (68 ± 7 years old, 20% females) with stable chronic heart failure due to reduced left ventricular ejection fraction (31 ± 8 %) participated in a single-group, pilot study assessing the feasibility and acceptability of a 12-week personalised home-based physical activity intervention aiming to increase daily number of steps by 2000 from baseline (Active-at-Home-HF). Patients completed cardiopulmonary exercise testing with non-invasive gas exchange and haemodynamic measurements and quality of life questionnaire pre- and post-intervention. Patients were supported weekly via telephone and average weekly step count data collected using pedometers. Results Forty-three patients were screened and 20 recruited into the study. Seventeen patients (85%) completed the intervention, and 15 (75%) achieved the target step count. Average step count per day increased significantly from baseline to 3 weeks by 2546 (5108 ± 3064 to 7654 ± 3849, P = 0.03, n = 17) and was maintained until week 12 (9022 ± 3942). Following completion of the intervention, no adverse events were recorded and quality of life improved by 4 points (26 ± 18 vs. 22 ± 19). Peak exercise stroke volume increased by 19% (127 ± 34 vs. 151 ± 34 m/beat, P = 0.05), while cardiac index increased by 12% (6.8 ± 1.5 vs. 7.6 ± 2.0 L/min/m2, P = 0.19). Workload and oxygen consumption at anaerobic threshold also increased by 16% (49 ± 16 vs. 59 ± 14 watts, P = 0.01) and 10% (11.5 ± 2.9 vs. 12.8 ± 2.2 ml/kg/min, P = 0.39). Conclusion The Active-at-Home-HF intervention is feasible, acceptable and effective for increasing physical activity in CHF. It may lead to improvements in quality of life, exercise tolerance and haemodynamic function. Trial Registration www.clinicaltrials.gov NCT0367727. Retrospectively registered on 17 September 2018.

scholarly journals Supplementation of l -Alanyl- l -Glutamine and Fish Oil Improves Body Composition and Quality of Life in Patients With Chronic Heart Failure

2015 ◽  
Vol 8 (6) ◽  
pp. 1077-1087 ◽  
Author(s):  
Christina Wu ◽  
Tomoko S. Kato ◽  
Ruiping Ji ◽  
Cynthia Zizola ◽  
Danielle L. Brunjes ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Body Composition ◽  
Chronic Heart Failure ◽  
Fish Oil

scholarly journals Effectiveness of Non-Animal Chondroitin Sulfate Supplementation in the Treatment of Moderate Knee Osteoarthritis in a Group of Overweight Subjects: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2027 ◽  
Author(s):  
Mariangela Rondanelli ◽  
Valentina Braschi ◽  
Clara Gasparri ◽  
Mara Nichetti ◽  
Milena Anna Faliva ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Pilot Study ◽  
Confidence Interval ◽  
Chondroitin Sulfate ◽  
Animal Origin ◽  
Inflammation Markers ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Overweight Subjects

Osteoarthritis (OA) is the most common form of arthritis in the world and is characterized by pain, various disabilities and loss of quality of life. Chondroitin sulfate (CS) is recommended as first-line therapy. CS of non-animal origin is of great interest for safety and sustainability reasons. This study aims to investigate the anti-inflammatory effects, anti-pain and ability-enhancement of a short-term supplementation with non-animal CS in overweight subjects with OA. In a randomized, double-blind, placebo-controlled pilot study, 60 overweight adults with symptomatic OA were allocated to consume 600 mg of non-animal CS (n = 30) or a placebo (n = 30) daily for 12 consecutive weeks. The assessment of knee-pain, quality of life, related inflammation markers and body composition was performed at 0, 4 and 12 weeks. The Tegner Lysholm Knee Scoring (TLKS) scale of the experimental group showed a statistically significant increase (+10.64 points; confidence interval (95% confidence interval (CI) 5.57; 15.70; p < 0.01), while the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score decreased (−12.24 points; CI 95% −16.01; −8.38; p < 0.01). The results also showed a decrease in the C-reactive protein (CRP) level (−0.14 mg/dL, CI 95% −0.26; −0.04; p < 0.01) and erythrocyte sedimentation rate (ESR) level (−5.01 mm/h, CI 95% −9.18; −0.84, p < 0.01) as well as the visual analogue scale (VAS) score in both knees. In conclusion, this pilot study demonstrates the effectiveness of non-animal CS supplementation in overweight subjects with knee OA in improving knee function, pain and inflammation markers.

scholarly journals Health-Related Quality of Life in Relation to Different Levels of Disease Severity in Patients with Chronic Heart Failure

2005 ◽  
Vol 8 (1) ◽  
pp. 39-45 ◽  
Author(s):  
Kazuhiro P. Izawa ◽  
Satoshi Watanabe ◽  
Kazuto Omiya ◽  
Sumio Yamada ◽  
Koichiro Oka ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Chronic Heart Failure ◽  
Disease Severity ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Different Levels
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