Inhibitory effects of an ethyl acetate fraction from Cephalonoplos segetum on inflammatory mediators from lipopolysaccharide-induced RAW 264.7 macrophages

2012 ◽  
Vol 55 (1) ◽  
pp. 41-46 ◽  
Author(s):  
Jin Mi Chun ◽  
Myeong Sook Cheon ◽  
Mikyung Park ◽  
A. Yeong Lee ◽  
Byeong Cheol Moon ◽  
...  
Keyword(s):  
Ethyl Acetate ◽  
Inflammatory Mediators ◽  
Ethyl Acetate Fraction ◽  
Raw 264.7 ◽  
Inhibitory Effects ◽  
Raw 264.7 Macrophages

Erratum to: Red Ginseng Ethanol Extract Suppressed Ag I/II-induced Up-expression of Inflammatory Mediators in RAW 264.7 Macrophages

2016 ◽  
Vol 44 (2) ◽  
pp. 227-227
Author(s):  
Kyung-Min Choi ◽  
Seung-Mi Hwang ◽  
Ji-Ye Lim ◽  
Eun-Sil Ko ◽  
Jong-Hyuk Park ◽  
...  
Keyword(s):  
Inflammatory Mediators ◽  
Ethanol Extract ◽  
Raw 264.7 ◽  
Red Ginseng ◽  
Raw 264.7 Macrophages

Inhibitory effects of cranberry polyphenol and volatile extracts on nitric oxide production in LPS activated RAW 264.7 macrophages

2019 ◽  
Vol 10 (11) ◽  
pp. 7091-7102 ◽  
Author(s):  
Katie Moore ◽  
Luke Howard ◽  
Cindi Brownmiller ◽  
Inah Gu ◽  
Sun-Ok Lee ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Inhibitory Effects ◽  
Raw 264.7 Macrophages ◽  
Oxide Production ◽  
Health Promoting

Cranberry volatiles have received little attention for health-promoting properties.

Inhibitory effects of ivermectin on nitric oxide and prostaglandin E2 production in LPS-stimulated RAW 264.7 macrophages

2009 ◽  
Vol 9 (3) ◽  
pp. 354-359 ◽  
Author(s):  
Xuemei Zhang ◽  
Yu Song ◽  
Huanzhang Xiong ◽  
Xinxin Ci ◽  
Hongyu Li ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Prostaglandin E2 ◽  
Raw 264.7 ◽  
Inhibitory Effects ◽  
Raw 264.7 Macrophages

scholarly journals Effect of the Extract and Constituents From Hancornia speciosa Fruits in Osteoclasts

2019 ◽  
Vol 6 (01) ◽  
pp. e7-e14 ◽  
Author(s):  
Micena Alves e Silva ◽  
Cinthia Pacheco ◽  
Mila Madeira ◽  
Adriana Saraiva ◽  
Elisângela de Freitas ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Ethyl Acetate ◽  
Bone Marrow Cell ◽  
Cell Cultures ◽  
Marrow Cell ◽  
Ethanolic Extract ◽  
Quinic Acid ◽  
Ethyl Acetate Fraction ◽  
Raw 264.7 ◽  
Hancornia Speciosa

Abstract Hancornia speciosa is a medicinal species traditionally used in Brazilian folk medicine to treat a variety of conditions. Compounds isolated from the leaves, bark, and trunk of this plant have shown therapeutic properties, but only recently have the fruits of H. speciosa been explored for potential pharmacological applications. The present study investigated the effects of an ethanolic extract from the fruits, fractions, and compounds thereof in bone resorbing cells. Primary osteoclast cultures from bone marrow cells and osteoclasts derived from a monocyte/macrophage cell line, RAW 264.7, were incubated with different concentrations of the ethanolic extract, ethyl acetate fraction, water fraction, quinic acid, and L-(+)-bornesitol. In RAW 264.7 cell cultures, quinic acid significantly reduced osteoclast formation. In bone marrow cell-derived osteoclasts, the ethyl acetate fraction induced a decrease in the number of osteoclasts, promoting a remarkable reduction in the mean area of those cells and in their resorption activity. The compounds quinic acid and bornesitol also affected bone marrow cell-derived osteoclasts. In both cell cultures, the substances tested did not affect cell viability/proliferation. In conclusion, components extracted from H. speciosa fruit affected the cells responsible for bone resorption, making them promising tools for interference in osteoclastogenesis.

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