Ameliorative potential of Sterculia tragacantha aqueous extract on renal gene expression and biochemical parameters in streptozotocin-induced diabetic rats

2020 ◽  
Vol 51 (1) ◽  
pp. 103-113
Author(s):  
Basiru Olaitan Ajiboye ◽  
Babatunji Emmanuel Oyinloye ◽  
Precious Ekong Essien ◽  
Sunday Amos Onikanni ◽  
Oluwafemi Adeleke Ojo ◽  
...  
Keyword(s):  
Gene Expression ◽  
Aqueous Extract ◽  
Biochemical Parameters ◽  
Diabetic Rats

Yerba Maté (Ilex paraguariensis) Aqueous Extract Decreases Intestinal SGLT1 Gene Expression but Does Not Affect Other Biochemical Parameters in Alloxan-Diabetic Wistar Rats

2008 ◽  
Vol 56 (22) ◽  
pp. 10527-10532 ◽  
Author(s):  
Daniela M. Oliveira ◽  
Helayne S. Freitas ◽  
Marina F. F. Souza ◽  
Demetrius P. Arçari ◽  
Marcelo L. Ribeiro ◽  
...  
Keyword(s):  
Gene Expression ◽  
Aqueous Extract ◽  
Biochemical Parameters ◽  
Wistar Rats ◽  
Ilex Paraguariensis

An aqueous extract fromMoringa oleiferaleaves ameliorates hepatotoxicity in alloxan-induced diabetic rats

2017 ◽  
Vol 95 (4) ◽  
pp. 524-530 ◽  
Author(s):  
Mabrouk Attia Abd Eldaim ◽  
Ahmed Shaban Abd Elrasoul ◽  
Samy Ahmed Abd Elaziz
Keyword(s):  
Gene Expression ◽  
Lipid Peroxidation ◽  
Aqueous Extract ◽  
Caspase 3 ◽  
Diabetic Rats ◽  
Control Group ◽  
Albino Rats ◽  
Hepatic Lipid ◽  
The Third ◽  
Hepatic Lipid Peroxidation

This study was carried out to evaluate the possible mechanisms through which an aqueous extract from MO leaves demonstrates hepatoprotective effects in alloxan-induced diabetic rats. Eighty albino rats were assigned to 4 groups. The control group was orally administered sterile saline. The second group was injected with alloxan (150 mg/kg body mass (b.m.)) by intraperitoneal injection (i.p.). The third group was given MO (250 mg/kg b.m.) orally, daily. The fourth group was injected with alloxan, as for the second group, and administrated an aqueous extract of MO leaves, as for the third group. Alloxan induced degenerative changes in hepatic and pancreatic tissues, increased hepatic lipid peroxidation, and increased gene expression of PC and caspase 3. However, it decreased the activities of hepatic SOD and CAT, and gene expression of GS. In contrast, the MO extract prevented changes to the histoarchitecture of hepatic and pancreatic tissues and normalized the reduced hepatic levels of glutathione, as well as the activities of SOD and CAT, and the gene expression of GS, while reducing blood glucose levels, hepatic lipid peroxidation, and the gene expression of PC and caspase 3. This study indicated that an aqueous extract of MO leaves can be a potent antioxidant and used as an hepatoprotective agent.

Effects of Aqueous Extract of Leaves of Abrus precatorius (Linn) on some Biochemical Parameters in Normal and Alloxan Induced Diabetic Rats

2017 ◽  
Vol 12 (2) ◽  
pp. 44-48
Author(s):  
Wakawa Henry Yusufu ◽  
Oluwayemisi Tanimowo ◽  
Sa`adatu Aliyu Abubakar ◽  
Fasihuddin Badruddin Ahmad
Keyword(s):  
Aqueous Extract ◽  
Biochemical Parameters ◽  
Diabetic Rats ◽  
Abrus Precatorius

Effect of aqueous extract of Hibiscus sabdariffa on some biochemical parameters in alloxan-induced diabetic rats

2014 ◽  
Vol 23 (6) ◽  
pp. 1675-1680 ◽  
Author(s):  
Patrick Emeka Aba ◽  
Chioma Uchenna Nwaigwe ◽  
Flora Ogbonne Okwuagwu ◽  
Samuel Chukwuneke Udem ◽  
Isaac Uzoma Asuzu
Keyword(s):  
Aqueous Extract ◽  
Biochemical Parameters ◽  
Diabetic Rats ◽  
Hibiscus Sabdariffa
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