scholarly journals Clinical Efficacy of Conservative Treatment with Micronized Purified Flavonoid Fraction in Female Patients with Pelvic Congestion Syndrome

2021 ◽  
Author(s):  
Rustem V. Akhmetzianov ◽  
Roman A. Bredikhin
2018 ◽  
pp. 27-35
Author(s):  
E. A. Zagryadskiy ◽  
A. M. Bogomazov ◽  
E. B. Golovko

OBJECTIVE. Determine the frequency of clinical manifestations of hemorrhoids and constipation in people seeking advice about hemorrhoids. In the course of the treatment of patients with hemorrhoids phlebotropic evaluate the effectiveness of therapy micronized purified flavonoid fraction (MPFF). MATERIALS AND METHODS. This multicenter study, including screening and observation part, which is part of the International Research «CHORUS» (Chronic venous and hemorrhoid diseases evaluation and scientific research), conducted in nine centers in different regions of Russia, 80 doctors of Coloproctology. In the screening group included 2668 patients who had investigated the incidence of constipation, as a risk factor for hemorrhoids. Conservative treatment, the foundation of which was, Moffitt therapy, received 1952 patients with stage I-IV hemorrhoids. Evaluating the effectiveness of the treatment was evaluated on the basis of a questionnaire. RESULTS. The questionnaire shows that constipation suffered - 766 (28,8 %) patients. Violation of defecation patterns and changes in stool consistency was observed in 1155 (43,9%) and 633 (25.5 %), respectively. At the same time, 288 (11,1 %) indicated a tendency to loose stools and diarrhea. Conservative treatment, the foundation of which is phlebotropic MPFF therapy conducted in patients of observational group has shown its efficiency in all grades of hemorrhoids. During the entire observation period of conservative treatment was effective in 1489 (76,3 %) patients. Surgical treatment was performed in 463 (23 %) patients grade I-IV hemorrhoids, the main part of patients with grade III -199 (43,1 %) and grade IV hemorrhoids - 68 (64,2 %). CONCLUSION. Conservative treatment of hemorrhoid disease, which is the basis on phlebotropic MPFF therapy, is effective at all stages of hemorrhoids, but in patients with grade III and grade IV disease requires surgical treatment.


2021 ◽  
Vol Volume 17 ◽  
pp. 591-600
Author(s):  
Michèle Cazaubon ◽  
Jean-Patrick Benigni ◽  
Marcio Steinbruch ◽  
Violaine Jabbour ◽  
Christelle Gouhier-Kodas

2017 ◽  
Vol 4 (11) ◽  
pp. 3590
Author(s):  
Ambreen Mannan ◽  
Tek Chnad Maheshwari ◽  
Suhail Ahmed Soomro

Background: To evaluate the patients with primary hemorrhoids after employing mainly the non-surgical treatment in all degree hemorrhoids.Methods: A prospective and descriptive study over three hundred and fifty (350) patients in four-year period. Concomitant anal fissure, anal fistula, secondary hemorrhoids, and recurrent hemorrhoids were excluded from the study.Results: Total 350 patients (age range-18-80 years). Female340 (97.14%) and male10 (2.58%) admitted in surgical OPD of three different hospitals during the period of Feb 2013- Jan 2017. All patients were thoroughly examined abdominally and per rectally and proctoscopied as well to rule out concomitant pelvic and perineal pathologies. All proctoscopic findings and treatment were done by single surgeon. Treatment of hemorrhoids was categorized into three types. Type I, conservative (fiber +oral lubricants + in jeer + micronized purified flavonoid fraction + sitz bath), type II, injection sclerotherapy & type III, surgery (open Hemorrhoidectomy). All degree hemorrhoids were first kept on conservative treatment and followed weekly for bleeding and hemorrhoid swelling. Only 38.57% required Injection sclerotherapy in cases where conservative treatment was failed, large hemorrhoid swelling (> 2cm size) seen on first proctoscopy and in cases where frequent fresh bleeding episodes found either on every 2nd-3rd day or every passage of stool. Strangulated bleeding hemorrhoids dealt with anal strapping, conservative treatment and later with injection sclerotherapy, which was given after resolution of bleeding and strangulation. Open hemorrhoidectomy was done in non-compliant and in patients with exclusive external hemorrhoids.Conclusions: Although conservative oral therapy has been given appreciating results but in adjunct with injection sclerotherapy the optimal results were promising.


2016 ◽  
pp. 52-57
Author(s):  
S.I. Zhuk ◽  
◽  
A.N. Grigorenko ◽  
A.A. Shluakhtina ◽  
◽  
...  

Aim of research is clinical, laboratory and instrumental evaluation of efficiency of proposed pathogenetic conservative treatment for Pelvic Congestion Syndrome in women of reproductive age. Complex treatment consisted of oral use of diosmin, chondroitin sulfate for 6 months and physiotherapy. The results of the study suggest that proposed treatment is effective enough. It provides recovery of varicose veins endothelium functions, dynamic balance between vasodilatory and vasoconstrictor factors, normalization of blood rheology and metabolic processes in connective tissue. Key words: Pelvic Congestion Syndrome, conservative treatment, venotonic therapy.


VASA ◽  
2016 ◽  
Vol 45 (4) ◽  
pp. 275-282 ◽  
Author(s):  
Christina Jeanneret ◽  
Konstantin Beier ◽  
Alexander von Weymarn ◽  
Jürg Traber

Abstract. Knowledge of the anatomy of the pelvic, gonadal and renal veins is important to understand pelvic congestion syndrome (PCS) and left renal vein compression syndrome (LRCS), which is also known as the nutcracker syndrome. LRCS is related to PCS and to the presence of vulvar, vaginal and pudendal varicose veins. The diagnosis of the two syndromes is difficult, and usually achieved with CT- or phlebography. The gold standard is the intravenous pressure measurement using conventional phlebography. The definition of PCS is described as pelvic pain, aggravated in the standing position and lasting for more than 6 months. Pain in the left flank and microhaematuria is seen in patients with LRCS. Women with multiple pregnancies are at increased risk of developing varicose vein recurrences with pelvic drainage and ovarian vein reflux after crossectomy and stripping of the great saphenous vein. The therapeutic options are: conservative treatment (medroxyprogesteron) or interventional (coiling of the ovarian vein) or operative treatment (clipping of the ovarian vein). Controlled prospective trials are needed to find the best treatment.


2016 ◽  
Vol 76 (10) ◽  
Author(s):  
A Jurga-Karwacka ◽  
GM Karwacki ◽  
FD Schwab ◽  
A Schötzau ◽  
C Zech ◽  
...  

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