scholarly journals Multiple antihypertensive use and risk of mortality in residents of aged care services: a prospective cohort study

2019 ◽  
Vol 32 (8) ◽  
pp. 1541-1549 ◽  
Author(s):  
Miriam Kerry ◽  
J. Simon Bell ◽  
Claire Keen ◽  
Janet K. Sluggett ◽  
Jenni Ilomäki ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Aged Care ◽  
Care Services ◽  
Risk Of Mortality

scholarly journals Normal serum aminotransferase concentration and risk of mortality from liver diseases: prospective cohort study

BMJ ◽  
2004 ◽  
Vol 328 (7446) ◽  
pp. 983 ◽  
Author(s):  
Chang Kim Hyeon ◽  
Mo Nam Chung ◽  
Ha Jee Sun ◽  
Hyub Han Kwang ◽  
Dae Kyu Oh ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Liver Diseases ◽  
Normal Serum ◽  
Serum Aminotransferase ◽  
Risk Of Mortality

Assessment of need for lower level acuity critical care services at a tertiary acute care hospital in Canada: A prospective cohort study

2019 ◽  
Vol 53 ◽  
pp. 91-97
Author(s):  
Olivia Haun de Oliveira ◽  
Ruxandra Pinto ◽  
Tracey DasGupta ◽  
Leda Sirtartchouck ◽  
Laura Rashleigh ◽  
...  
Keyword(s):  
Critical Care ◽  
Cohort Study ◽  
Acute Care ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Acute Care Hospital ◽  
Care Hospital ◽  
Care Services ◽  
Assessment Of Need

scholarly journals Mortality risk of bloodstream infection caused by either Escherichia coli or Klebsiella pneumoniae producing extended-spectrum β-lactamase: a prospective cohort study

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Osman Sianipar ◽  
Widya Asmara ◽  
Iwan Dwiprahasto ◽  
Budi Mulyono
Keyword(s):  
Escherichia Coli ◽  
Cohort Study ◽  
Klebsiella Pneumoniae ◽  
Bloodstream Infection ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
E Coli ◽  
Extended Spectrum ◽  
Risk Of Mortality

Abstract Objective Several studies reported that infection of extended-spectrum β lactamase (ESBL)-producing Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae) contributed to higher mortality rates but others found it was not associated with mortality. A prospective cohort study which involved 72 patients was conducted to assess the risk of mortality of bloodstream infection due to ESBL-producing K. pneumoniae or E. coli as compared to those infected by either K. pneumoniae or E. coli which not produce ESBL. Result Mortality in the group of patients infected with ESBL-producing bacteria was 30.6%, whereas in another group which was infected with non ESBL-producing bacteria was 22.2% (p = 0.59). Kaplan–Meier’s analysis showed that the survival rate during 14-days follow-up among these two group was not significantly different (p = 0.45) with hazard ratio 1.41 (95% CI  0.568–3.51). Stratification analysis found that adult and elderly patients, patients with sign of leukocytosis, and patients treated with carbapenem were modifier effect variables.

Mo1119 Opium Use and Risk of Mortality From Digestive Diseases – A Prospective Cohort Study

2013 ◽  
Vol 144 (5) ◽  
pp. S-583
Author(s):  
Masoud Malekzadeh ◽  
Hooman Khademi ◽  
Farin Kamangar ◽  
Akram Pourshams ◽  
Arash Etemadi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Digestive Diseases ◽  
Risk Of Mortality ◽  
Opium Use

scholarly journals Hospital Mortality and Resource Implications of Hospitalisation with COVID-19 in London, UK: A Prospective Cohort Study

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Savvas Vlachos ◽  
Adrian Wong ◽  
Victoria Metaxa ◽  
Sergio Canestrini ◽  
Carmen Lopez Soto ◽  
...  
Keyword(s):  
Critical Care ◽  
Cohort Study ◽  
Hospital Mortality ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Clinical Decision Making ◽  
Hospital Admissions ◽  
Resource Utilisation ◽  
Hospital Level ◽  
Care Services

Background. Coronavirus disease 2019 (COVID-19) had a significant impact on the National Health Service in the United Kingdom (UK), with over 35 000 cases reported in London by July 30, 2020. Detailed hospital-level information on patient characteristics, outcomes, and capacity strain is currently scarce but would guide clinical decision-making and inform prioritisation and planning. Methods. We aimed to determine factors associated with hospital mortality and describe hospital and ICU strain by conducting a prospective cohort study at a tertiary academic centre in London, UK. We included adult patients admitted to the hospital with laboratory-confirmed COVID-19 and followed them up until hospital discharge or 30 days. Baseline factors that are associated with hospital mortality were identified via semiparametric and parametric survival analyses. Results. Our study included 429 patients: 18% of them were admitted to the ICU, 52% met criteria for ICU outreach team activation, and 61% had treatment limitations placed during their admission. Hospital mortality was 26% and ICU mortality was 34%. Hospital mortality was independently associated with increasing age, male sex, history of chronic kidney disease, increasing baseline C-reactive protein level, and dyspnoea at presentation. COVID-19 resulted in substantial ICU and hospital strain, with up to 9 daily ICU admissions and 41 daily hospital admissions, to a peak census of 80 infected patients admitted in the ICU and 250 in the hospital. Management of such a surge required extensive reorganisation of critical care services with expansion of ICU capacity from 69 to 129 beds, redeployment of staff from other hospital areas, and coordinated hospital-level effort. Conclusions. COVID-19 is associated with a high burden of mortality for patients treated on the ward and the ICU and required substantial reconfiguration of critical care services. This has significant implications for planning and resource utilisation.

Mood disorders increase mortality mainly through dementia: A community-based prospective cohort study

2021 ◽  
pp. 000486742110419
Author(s):  
Hoyoung An ◽  
Hee Won Yang ◽  
Dae Jong Oh ◽  
Eunji Lim ◽  
Jin Shin ◽  
...  
Keyword(s):  
Cohort Study ◽  
Mood Disorders ◽  
Prospective Cohort Study ◽  
Indirect Effects ◽  
Prospective Cohort ◽  
Structural Equation ◽  
Bipolar Disorders ◽  
Direct Effects ◽  
Community Based ◽  
Risk Of Mortality

Objective: The effects of mood disorders on mortality may be mediated by their effects on the risk of dementia, and interventions to reduce the occurrence of dementia may reduce their overall mortality. This study aimed to investigate the direct effects of depressive and bipolar disorders on the 6-year risk of mortality and also their indirect effects on mortality due to their effect on the risk of dementia. Methods: A total of 5101 Koreans were selected from a community-based prospective cohort study, and 6-year risks of mortality and dementia in participants with depressive and bipolar disorders were estimated by Cox proportional hazard analysis. The direct and indirect effects of depressive and bipolar disorders on the risk of mortality were estimated using structural equation modeling. Results: The depressive and bipolar disorder groups showed 51% and 85% higher 6-year mortality, and 82% and 127% higher risk of dementia, respectively, compared to euthymic controls. The effects of depressive and bipolar disorders on mortality were mainly mediated by their effects on the risk of dementia in a structural equation model. The direct effects of each mood disorder on mortality were not significant. Conclusion: Both depressive and bipolar disorders increased the risks of mortality and dementia, and the effects of mood disorders on mortality were mainly mediated through dementia. As dementia occurs later in life than mood disorders, measures to prevent it may effectively reduce mortality in individuals with a history of mood disorders, as well as being more feasible than attempting to control other causes of death.

Unrestrained eating behavior and risk of mortality: a prospective cohort study

2021 ◽  
Author(s):  
Yin Zhang ◽  
Mingyang Song ◽  
Chen Yuan ◽  
Andrew T. Chan ◽  
Eva S. Schernhammer ◽  
...  
Keyword(s):  
Cohort Study ◽  
Eating Behavior ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Risk Of Mortality
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