HPV Testing Behaviors and Willingness to Use HPV Self-sampling at Home Among African American (AA) and Sub-Saharan African Immigrant (SAI) Women

Author(s):  
Adebola Adegboyega ◽  
Amanda T. Wiggins ◽  
Lovoria B. Williams ◽  
Mark Dignan
2021 ◽  
pp. sextrans-2020-054816
Author(s):  
Marijn C Verwijs ◽  
Stephen Agaba ◽  
Marie-Michele Umulisa ◽  
Janneke H H M van de Wijgert

ObjectivesTo establish temporal links between vaginal microbiota (VMB) data and incident clinical events, frequent longitudinal vaginal sampling is required. Self-collection of swabs at the participant’s home may be useful to avoid overburdening research clinics and participants. One-off vaginal self-sampling for STI or cervical cancer screening programmes has been shown to be feasible and acceptable to women in multiple studies, including in sub-Saharan Africa, but the feasibility and acceptability of frequent longitudinal vaginal sampling in the context of VMB sequencing studies is unknown.MethodsTwelve participants of a randomised clinical trial in Kigali, Rwanda, self-collected vaginal swabs three times a week for a month. We studied feasibility by comparing DNA concentrations, proportions of samples with >1000 16S rRNA amplicon sequencing reads and VMB composition outcomes of self-collected swabs with clinician-collected swabs. We evaluated the acceptability of self-collection using structured face-to-face interviews and a focus group discussion.ResultsThe participants collected vaginal swabs at 131 different time points. One woman stopped self-sampling after one try due to a social harm. All self-sampled swabs generated >1000 rRNA amplicon sequencing reads, and the DNA concentration of self-sampled swabs and clinician-sampled swabs did not differ significantly (Kruskal-Wallis p=0.484). Self-sampled and clinician-sampled swabs generated similar VMB composition data. Participants reported feeling very comfortable during self-sampling (11/12; 91.7%) and that self-sampling had become easier over time (12/12; 100%). They mentioned reduced travel time and travel costs as advantages of self-sampling at home.ConclusionsFrequent longitudinal vaginal sampling at home is feasible and acceptable to participants, even in the context of a low-resource setting, as long as adequate counselling is provided.Trial registration numberNCT02459665.


Author(s):  
Yih-Lan Chen ◽  
Hsing-Fu Cheng ◽  
Hui-Wen Tang ◽  
Chaochang Wang

Abstract To meet the challenges of internationalization, universities around the globe have implemented a variety of strategies, including study abroad, academic exchange, and cross-border collaboration. For any of these strategies, it was perhaps inevitable that English would become a crucial means of communication for both native and non-native speakers. The current study investigates the relationship between domestic college students’ perceptions of English varieties (PEV), L2 motivation, and willingness to communicate (WTC) in the internationalization at home (IaH) context. A model linking PEV, L2 motivation, and WTC was proposed. A total of 273 college students at a university in Taiwan responded to a questionnaire consisting of 16 items in four major categories. The results indicate that in the IaH context college students’ PEV significantly affects L2 motivation and only when learners are intrinsically motivated are they willing to communicate interculturally using English. The results suggest that promoting an appreciation for English varieties in the college context strengthens students’ intrinsic motivation to learn English, which may promote the students’ willingness to use English for communication.


2013 ◽  
Vol 23 (2) ◽  
pp. e123-e130 ◽  
Author(s):  
Isabel C. Scarinci ◽  
Allison G. Litton ◽  
Isabel C. Garcés-Palacio ◽  
Edward E. Partridge ◽  
Philip E. Castle

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