Burden and Expressed Emotion in Caregivers of Bipolar Affective Disorder-Mania: A Cross-Sectional Study

2018 ◽  
Vol 5 (1) ◽  
pp. 83-88 ◽  
Author(s):  
Arun Kumar Yadav ◽  
Seema Parija ◽  
Jyoti Yadav ◽  
Ashok Kumar Patel ◽  
Prashant Mishra
Author(s):  
Rajendra Kumar Acharya ◽  
Rahul Gupta ◽  
Sanjay Gehlot

Background: Nervous tissue is extremely sensitive to oxidative damage Recent studies show an elevated level of oxidative stress indicators in Schizophrenia. Current studies on oxidative stress in Schizophrenia mainly focus on enzymatic antioxidants, while limited studies have been carried out on non-enzymatic antioxidants Some studies discovered that plasma non-enzymatic antioxidants (uric acid, bilirubin, and albumin) in Schizophrenia are lower than those of healthy controls. Aim: To compare levels of nonenzymatic antioxidants in Schizophrenia and bipolar illness. Material and Methods: The present study is a hospital_ based cross-sectional study conducted among 100 patients with Schizophrenia and Bipolar Affective disorder included as per inclusion and exclusion criteria and undergone psychiatric assessment as per diagnostic criteria. Results: S. albumin, S.bilirubin, S.uric acid were found to be low in Schizophrenia but statistically, the significant difference was evaluated for S.uric acid. Conclusion: S. uric acid lower significant levels in Schizophrenia as compared to bipolar affective disorder shows the more impaired peripheral antioxidant scavenging system in Schizophrenia. However, pure peripheral antioxidant system dysfunction could not be ascertained in Schizophrenia through this study. Keywords: nonenzymatic antioxidants, Schizophrenia, bipolar illness.


2010 ◽  
Vol 25 (4) ◽  
pp. 216-219 ◽  
Author(s):  
R. Hou ◽  
V. Cleak ◽  
R. Peveler

AbstractAdherence to medication is essential for achieving good outcomes for patients with bipolar affective disorder. This study tested whether treatment and illness beliefs are important predictors of adherence to medication. Results indicate that beliefs are predictive, and may be a suitable target for modification in efforts to change behaviour.


Author(s):  
Deependra Prasad Sarraf ◽  
Suraj Nepal

<p class="abstract"><strong>Background:</strong> Benefits of lithium maintenance therapy in bipolar affective disorder (BPAD) are restricted by adverse drug reactions (ADRs) and low therapeutic index. The same dose of lithium has sub-therapeutic, therapeutic and supra-therapeutic serum level in different patients. The objective of this study was to describe the pattern of ADR and serum concentration of maintenance dose of lithium in patients with BPAD.</p><p class="abstract"><strong>Methods:</strong> A cross-sectional study was conducted in patients diagnosed with BPAD and taking lithium monotherapy 900 mg daily at least for 6 months at outpatient department of psychiatry, B. P. Koirala institute of health sciences. Sociodemographic profile and relevant laboratory investigations were recorded on a self-designed proforma. Chi square test, ANOVA test and student’s t test were used for analysing the data at p value &lt;0.05.</p><p class="abstract"><strong>Results:</strong> Out of 123, 64 (52.0%) were female. Serum concentration ranged from 0.31 to 1.51 mmol/l with mean of 0.803 mmol/l and was in therapeutic range in 104 (84.6%) patients. At least one ADR was seen in 81 (65.9%) patients and hand tremor (43.6%) was the commonest ADR. Hypothyroidism and hyperthyroidism were seen in 9 (6.8%) and 6 (4.5%) patients, respectively. Occurrence of ADRs were more in female and was significantly significant (P value &lt;0.05).</p><p class="abstract"><strong>Conclusions:</strong> The serum level of lithium 900 mg/day varied widely and was in therapeutic range in majority of the patients. Prevalence of ADRs was 65.9%. Occurrence of ADRs were significantly more common in female patients and supra-therapeutic serum concentration of lithium. A prospective long-term study should be conducted to validate the study findings.</p>


2016 ◽  
Vol Ano 6 ◽  
pp. 14-26
Author(s):  
Fabiano Araújo Cunha ◽  
Fernando de Oliveira Costa ◽  
Luís Otávio de Miranda Cota ◽  
José Roberto Cortelli ◽  
Fernando Silva Neves

Embora pouco investigado e com dados conflitantes, o transtorno afetivo bipolar (TABP) é um fator comportamental que pode apresentar influência sobre a periodontite. Os objetivos deste estudo foram: 1) determinar a prevalência de periodontite em uma população com diagnóstico de TABP; 2) verificar a influência de variáveis de risco na associação entre o TABP e a periodontite. O estudo foi composto por uma amostra de conveniência de 156 indivíduos com TABP, selecionados no Hospital de Saúde Mental anexo ao Hospital das Clínicas da Universidade Federal de Minas Gerais. Os pacientes foram avaliados através de parâmetros clínicos periodontais e variáveis de risco sociodemográficas. Os resultados demostraram uma prevalência de 59% de periodontite entre os indivíduos com TABP. Destes, 90,2% apresentavam periodontite crônica moderada e 9,8% a forma avançada. Quanto à extensão da periodontite, em 81,5% a doença apresentouse de forma localizada e em 18,5% de forma generalizada. Concluiu-se que os pacientes com TABP apresentaram uma alta prevalência de doença periodontal (56,8%), confirmando a importância da prevenção, diagnóstico e tratamento desta patologia, a qual possa, no futuro, ser considerada como mais uma comorbidade associada a essa doença psiquiátrica. Salienta-se a necessidade de estudos futuros que comprovem a associação entre o TABP e a periodontite, particularmente os de delineamento longitudinal e ensaios clínicos randomizados.


2020 ◽  
pp. 18-24
Author(s):  
Thaís de Souza Rosa ◽  
Raissa Carvalho Marinho ◽  
Wemerson Davi de Miranda ◽  
Brisa Gomes Cangussú ◽  
Laís Tonello ◽  
...  

Introduction: Mental disorders are changes in psychological, mental or cognitive functioning, in which there is impairment, or suffering that impairs life habits, family, social interaction, among others. Objective: To trace the epidemiological profile of psychiatry patients of Gurupi polyclinic -TO. Materials and Methods: Descriptive cross-sectional study with a quantitative approach, performed from the analysis of 104 medical records of patients in the psychiatric specialty attended at Gurupi-TO polyclinic. Data were collected on gender, age, the city of origin, the profession, marital status and medical diagnosis. The data were analyzed from descriptive statistics, in absolute and relative values. Results: It was observed that people aged 6 to 84 years were observed, most of them female (63.5%). In addition, it is noticed that polyclinic users are mostly single (70%), residents of Gurupi city (84%). Regarding the profession, a high percentage of medical records do not contain these responses (58%), of the others are mostly from home (15%). The most prevalent disorders are bipolar affective disorder (34.2%) and depression (27.9%). Conclusion: It is possible to realize that psychiatric disorders are predominantly affecting female patients, aged between 30 and 49 years, single, as a profession of "home", with fixed residence in the city of Gurupi and diagnosed predominantly with mental pathologies related to bipolar affective disorder and depression.


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