Infection Control in the ICU: Gram-Negative Bacteria

2012 ◽  
Keyword(s):  
Infection Control ◽  
Gram Negative Bacteria ◽  
Gram Negative

Determination of carbapenemase genes in clinical isolates using Cepheid Xpert Carba-R

2021 ◽  
pp. 16-19
Author(s):  
N. I. Gabrielyan ◽  
V. G. Kormilitsyna ◽  
V. K. Zaletaeva ◽  
A. V. Krotevich ◽  
I. A. Miloserdov ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
Infection Control ◽  
Resistance Genes ◽  
Carbapenem Resistance ◽  
Critical Issue ◽  
Sensitivity Study ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Carbapenem Resistant

Detection of carbapenem resistance genes is a critical issue for hospitals due to possible recommendations for infection control and targeted therapy. The Cepheid Xpert instrument, a Carba-R test for the detection and differentiation of five common carbapenemase genes, was tested from September 2020 to February 2021. As part of the approbation, 20 tests were provided. This review presents the results of the approbation of a relatively regular sensitivity study on Siemens WalkAway‑96 plus. Cepheid Xpert Carba-R analysis has been shown to be an accurate and fast tool for detecting colonization by carbapenem-resistant gram-negative bacteria, which can help limit the spread of these organisms in hospitals.

scholarly journals A pragmatic approach to screening for transmissible resistance in the Enterobacteriaceae

2010 ◽  
Vol 31 (3) ◽  
pp. 106
Author(s):  
Justin Ellem ◽  
Jon Iredell
Keyword(s):  
Infection Control ◽  
Resistance Genes ◽  
Gram Negative Bacteria ◽  
Transmission Characteristics ◽  
Pragmatic Approach ◽  
Gram Negative

Determining the origin, spread and characteristics of important resistance genes and plasmids in Gram-negative bacteria may be more informative than determining the epidemiology of bacteria themselves. Infection control resistance surveillance and containment efforts should focus on the transmission characteristics of the resistance rather than those of the index organism at the point of recognition.

Variation in Definitions and Isolation Procedures for Multidrug-Resistant Gram-Negative Bacteria: A Survey of the Society for Healthcare Epidemiology of America Research Network

2014 ◽  
Vol 35 (4) ◽  
pp. 362-366 ◽  
Author(s):  
Marci Drees ◽  
Lisa Pineles ◽  
Anthony D. Harris ◽  
Daniel J. Morgan
Keyword(s):  
Infection Control ◽  
Online Survey ◽  
Multidrug Resistant ◽  
Research Network ◽  
Gram Negative Bacteria ◽  
Emerging Pathogens ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Gram Negative ◽  
Healthcare Epidemiology

Objective.To assess definitions, experience, and infection control practices for multidrug-resistant gram-negative bacteria (MDR-GNB), including Enterobacteriaceae, Acinetobacter, and Pseudomonas species, in acute care hospitals.Design.Cross-sectional survey.Participants.US and international members of the Society for Healthcare Epidemiology of America (SHEA) Research Network.Methods.Online survey that included definitions, infection control procedures, and microbiology capability related to MDR-GNB and other MDR bacteria.Results.From November 2012 through February 2013, 66 of 170 SHEA Research Network members responded (39% response rate), representing 26 states and 15 countries. More than 80% of facilities reported experience with each MDR-GNB isolate, and 78% had encountered GNB resistant to all antibiotics except colistin (62% Acinetobacter, 59% Pseudomonas, and 52% Enterobacteriaceae species). Participants varied regarding their definitions of “multidrug resistant,” with 14 unique definitions for Acinetobacter, 18 for Pseudomonas, and 22 for Enterobacteriaceae species. Substantial variation also existed in isolation practices. Although isolation was commonly used for methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and carbapenem-resistant Enterobacteriaceae (CRE), approximately 20% of facilities did not isolate for MDR Pseudomonas or Acinetobacter. The majority of those that isolated MDR organisms also removed isolation using a wide variety of criteria.Conclusion.Facilities vary significantly in their approach to preventing MDR-GNB transmission. Although practices for MRSA and VRE are relatively standardized, emerging pathogens CRE and other MDR-GNB have highly varied definitions and management. This confusion makes communication difficult, and varied use of isolation may contribute to emergence of these organisms. Public health agencies need to promote standard definitions and management to enable broader initiatives to limit emergence of MDR-GNB.

Infection Control in the ICU: Gram-Negative Bacteria

2012 ◽  
pp. 1213-1216
Author(s):  
G. Citerio ◽  
C. Giussani ◽  
Hugo Sax ◽  
Didier Pittet ◽  
Xiaoyan Wen ◽  
...  
Keyword(s):  
Infection Control ◽  
Gram Negative Bacteria ◽  
Gram Negative

scholarly journals Detection of Gram-Negative Bacteria in Patients and Hospital Environment at a Room in Geriatric Wards under the Infection Control against MRSA

2001 ◽  
Vol 75 (2) ◽  
pp. 144-150 ◽  
Author(s):  
Hironori MASAKI ◽  
Norichika ASOH ◽  
Misao TAO ◽  
Hideki IKEDA ◽  
Satoshi DEGAWA ◽  
...  
Keyword(s):  
Infection Control ◽  
Hospital Environment ◽  
Gram Negative Bacteria ◽  
Gram Negative

Bacteriology of Blood, Wound, and Sputum Cultures from Non-US Casualties Treated in a Combat Support Hospital in Iraq

2008 ◽  
Vol 29 (10) ◽  
pp. 981-984 ◽  
Author(s):  
Kimberly A. Moran ◽  
Clinton K. Murray ◽  
Edwin L. Anderson
Keyword(s):  
Infection Control ◽  
Gram Negative Bacteria ◽  
Blood Samples ◽  
Gram Negative ◽  
Positive Results

A review of culture results from non-US casualties in Iraq revealed gram-negative bacteria were the most commonly isolated pathogens. Cultures of respiratory fluid yielded positive results earlier than cultures of wound or blood samples and potentially serve as an earlier marker of future infections. Continued aggressive infection control for non-US casualties is needed.

scholarly journals Implications of infection control care bundles: a 12-year surveillance study of bacteraemia caused by Gram-negative bacteria

2020 ◽  
Vol 13 (2) ◽  
pp. 351-352
Author(s):  
A. Al-Hamad ◽  
S. Alsada ◽  
S. Alshamlan ◽  
M. Alhowaidi ◽  
S. Alsheef ◽  
...  
Keyword(s):  
Infection Control ◽  
Surveillance Study ◽  
Gram Negative Bacteria ◽  
Care Bundles ◽  
Gram Negative

scholarly journals What Infection Control Interventions Should Be Undertaken to Control Multidrug-Resistant Gram-Negative Bacteria?

2006 ◽  
Vol 43 (Supplement_2) ◽  
pp. S57-S61 ◽  
Author(s):  
Anthony D. Harris ◽  
Jessina C. McGregor ◽  
Jon P. Furuno
Keyword(s):  
Infection Control ◽  
Multidrug Resistant ◽  
Gram Negative Bacteria ◽  
Gram Negative
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