Renal functional correlates of methyl mercury intoxication: Interaction with acute mercuric chloride toxicity

1977 ◽  
Vol 42 (2) ◽  
pp. 399-410 ◽  
Author(s):  
William E. Stroo ◽  
Jerry B. Hook
Keyword(s):  
Mercuric Chloride ◽  
Methyl Mercury ◽  
Chloride Toxicity ◽  
Mercury Intoxication

Histochemical and functional evaluation of mercuric chloride toxicity in cultured macrophages

1991 ◽  
Vol 23 (1-4) ◽  
pp. 306-315 ◽  
Author(s):  
M. Christensen ◽  
S. Ellermann-Eriksen ◽  
J. Rungby ◽  
S.C. Mogensen ◽  
G. Danscher
Keyword(s):  
Mercuric Chloride ◽  
Functional Evaluation ◽  
Chloride Toxicity

In vivo Amelioration of Oxidative Stress by Artemisia absinthium L. Administration on Mercuric Chloride Toxicity in Brain Regions

2016 ◽  
Vol 16 (5) ◽  
pp. 167-177 ◽  
Author(s):  
N. Hallal ◽  
O. Kharoubi ◽  
I. Benyettou ◽  
K. Tair ◽  
M. Ozaslan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mercuric Chloride ◽  
Brain Regions ◽  
Artemisia Absinthium ◽  
Chloride Toxicity

Microfilament and microtubule alterations in cultured CHO cells during methyl mercury intoxication and protection with selenite

1990 ◽  
Vol 22 ◽  
pp. 495
Author(s):  
Rita Vignani ◽  
Pier Egisto Valensin ◽  
Maria Letizia Bianchi ◽  
Bandinelli ◽  
Paolo Di Sinplicio
Keyword(s):  
Cho Cells ◽  
Methyl Mercury ◽  
Mercury Intoxication

Electron Capture Gas-Liquid Chromatographic Determination of Methyl Mercury in Fish and Shellfish: Collaborative Study

1983 ◽  
Vol 66 (5) ◽  
pp. 1121-1128 ◽  
Author(s):  
Susan C Hight ◽  
Stephen G Capar ◽  
◽  
J Anderson ◽  
J Brzezinski ◽  
...  
Keyword(s):  
Electron Capture ◽  
Reference Values ◽  
Mercuric Chloride ◽  
Methyl Mercury ◽  
Collaborative Study ◽  
Chromatographic Determination ◽  
Gas Liquid Chromatography ◽  
Mercury In Fish ◽  
Fish And Shellfish ◽  
Methyl Mercuric Chloride

Abstract A method for determining methyl mercury in fish and shellfish was collaboratively studied in 8 laboratories. Methyl mercury is isolated from acetonewashed, homogenized tissue by adding hydrochloric acid and extracting into benzene the methyl mercuric chloride that is formed. The benzene extract is concentrated and analyzed for methyl mercuric chloride by electron capture gas-liquid chromatography on 5% DEGS-PS treated with inorganic mercuric chloride solution. The quantitation limit for the method is 0.05 μg Hg/g. Each collaborator determined methyl mercury at 2 levels in blind duplicate samples of swordfish, tuna, oyster, and shrimp tissues. Both fortified and unfortified samples were analyzed. Methyl-bound mercury in the samples ranged from 0.15 to 148 μg Hg/g. The reproducibility coefficients of variation for the 8 samples ranged from 3 to 13%. The accuracy, measured by comparison to reference values, ranged from 99 to 120%. Reference values were determined in the Associate Referee's laboratory by replicate analyses of the fortified and unfortified samples. The method has been adopted official first action.

scholarly journals The Influence of Nutrition on Methyl Mercury Intoxication

2000 ◽  
Vol 108 ◽  
pp. 29 ◽  
Author(s):  
Laurie Chapman ◽  
Hing Man Chan
Keyword(s):  
Methyl Mercury ◽  
Mercury Intoxication

Protective role of melatonin in myocardial oxidative damage induced by mercury in murine model

2010 ◽  
Vol 30 (10) ◽  
pp. 1489-1500 ◽  
Author(s):  
Mitali Jindal ◽  
Gobind Rai Garg ◽  
Pramod Kumari Mediratta ◽  
Mohammad Fahim
Keyword(s):  
Drinking Water ◽  
Mercuric Chloride ◽  
Diastolic Pressure ◽  
Lipid Peroxide ◽  
Left Ventricular ◽  
Control Group ◽  
Albino Rats ◽  
Mercury Intoxication ◽  
Cardiovascular Functions

This study was designed to investigate the electrophysiological, hemodynamic and biochemical parameters of mercuric chloride and methylmercury exposure on cardiovascular functions and its modulation by melatonin in vivo. Wistar albino rats were divided into six group containing 10 animals each. Mercuric chloride (3.75 µM/L) in drinking water and methylmercury (0.5 mg/kg/day) through gavage, given for 1 month, induced a statistically significant increase ( p < 0.001) in left ventricular end diastolic pressure, blood and cardiac tissue mercury content and myocardial lipid peroxides compared to control. Significant attenuation ( p < 0.05) of baroreflex sensitivity and depletion of myocardial endogenous antioxidants ( p < 0.001) viz. Reduced glutathione (GSH) and superoxide dismutase (SOD) were also found in the mercury-exposed groups as compared to control group. Mercury exposure followed by subacute treatment with melatonin (4 µg/mL/day) in drinking water for 1 month significantly lowered ( p < 0.01) left ventricular end diastolic pressure and lipid peroxide levels and increased baroreceptor sensitivity ( p < 0.001) and also levels of GSH and SOD ( p < 0.001) as compared to mercury-exposed rats. The results of our study provide clear evidence that elevated oxidative stress and altered baroreflex mechanisms caused by mercury intoxication may be the contributing factors responsible for impairment of cardiovascular functions and melatonin may exhibit cardioprotective property against subacute heavy metal intoxication and enhance the antioxidant defense against mercury-induced oxidative myocardial injury in rats.

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